It’s nicknamed the Eternal City for a reason. In Rome, you can drink from a street fountain fed by an ancient aqueduct. Or see the same profile on a statue in the Capitoline Museum and the guy making your cappuccino. (Which, of course, you know never to order after 11 am.) Rome is also a city of contrasts—what other place on earth could be home to both the Vatican and La Dolce Vita?

History lovers should know that Milan is not all about trendy shops and designer clothes. Among the city's many historical attractions are La Scala Opera, the Milan Cathedral, the National Museum of Science and Technology and Santa Maria della Grazie, the church that preserves da Vinci's "Last Supper".

Breathe deep in Genting Highlands where, unlike nearby Kuala Lumpur, the air is fresh and clean. Aside from its resort life, visitors flock to hill station to enjoy cooler temperatures, mountain scenery, strawberry farms, and a relatively undisturbed, natural rain forest.

The capital of North Rhine-Westphalia, Dusseldorf is a regional economic powerhouse straddling the banks of the Rhine River. Altstadt is not just Dusseldorf's lovely old town, but also where the city's nightlife is based and where Altbier, its native dark beer, is plentiful. Dusselforfians take their beer seriously. Königsallee (Ko to the locals), Dusseldorf's famous shopping street, has many high-end stores. And the Museum Kunst Palast has one of the Rhineland's best art collections.