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p47phox and NOXO1, the Organizer Subunits of the NADPH Oxidase 2 (Nox2) and NADPH Oxidase 1 (Nox1)
The enzyme responsible for superoxide anion production in phagocytes is called the phagocyte NADPH oxidase. It is a multicomponent enzyme system...
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NADPH Oxidase-Dependent Processes in the Social Amoeba Dictyostelium discoideum
Dictyostelium discoideum, also known as social amoeba, is at the boundary between unicellular and multicellular life. This protist is a professional...
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The NADPH Oxidase Activator p67phox and Its Related Proteins
The Nox family NADPH oxidases can be divided into two groups based on the presence or absence of the Ca2+-binding EF-hand motif in the N-terminal...
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NADPH oxidase contributes to the production of reactive oxygen species in Chlorella pyrenoidosa
Reactive Oxygen Species (ROS) play an important role in oxidative stress and are related to the lipid accumulation in microalgae. Nicotinamide...
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Low dose radiation upregulates Ras/p38 and NADPH oxidase in mouse colon two months after exposure
BackgroundExposure to ionizing is known to cause persistent cellular oxidative stress and NADPH oxidase (Nox) is a major source of cellular oxidant...
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Multifunctional regulation of NADPH oxidase in growth, microsclerotia formation and virulence in Metarhizium rileyi
ObjectivesMicrosclerotia (MS), anti-stress structures produced by many filamentous fungi, have been proven to be a great substitute for conidia in...
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NADPH oxidase 4-mediating oxidative stress contributes to endometriosis
NADPH oxidase 4 (NOX4) plays an important role in the regulation of oxidative stress, which is associated with endometriosis. This study aims to...
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NADPH Oxidase 1: At the Interface of the Intestinal Epithelium and Gut Microbiota
NOX1 was the first of the NOX family of NADPH oxidases described with sequence homologous to the well-known microbicidal NADPH oxidase of phagocytes....
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Physiological Functions and Pathological Significance of NADPH Oxidase 3
NADPH oxidase 3 (NOX3) is the catalytic subunit of a superoxide-producing enzyme complex in the inner ear. Other subunits of this complex include...
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Discovery and Functional Analysis of the Single-Celled Yeast NADPH Oxidase, Yno1
In this chapter, we describe the discovery of the NADPH oxidase gene and protein of the single-celled yeast Saccharomyces cerevisiae, Yno1. This...
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NADPH Oxidases in Fungi
Synthesis of reactive oxygen species (ROS) by specific NADPH oxidases (Nox) can serve both defense and differentiation signalling roles in animals...
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On Katsuko Kakinuma: Spectroscopic Studies of Redox Centers in NADPH Oxidase – “Identifying and Observing the Key Players that Pass an Electron to Oxygen”
Dr. Katsuko Kakinuma made many important contributions to biology and medicine through the study of the neutrophil NADPH oxidase system, particularly...
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NADPH Oxidases in Arthropods
Arthropods, especially insects, have been used as physiological models for over a century. Once the microbicidal action of reactive oxygen species...
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Plant NADPH Oxidases
Reactive oxygen species (ROS) are signaling molecules that play important roles in many processes in plants, including development, immunity, and...
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NADPH oxidase mediated oxidative stress signaling in FLT3-ITD acute myeloid leukemia
The internal tandem duplication of the juxtamembrane domain of the FMS-like tyrosine kinase 3 (FLT3-ITD) is the most common genetic change in acute...
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NADPH Oxidases in Zebrafish
Zebrafish, a minnow family teleost fish, has emerged as a powerful in vivo vertebrate model system in biological research. Zebrafish have been used...
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Reactive oxygen species and NADPH oxidase-encoding genes underly the plant growth and developmental responses to Trichoderma
The modulation of plant growth and development through reactive oxygen species (ROS) is a hallmark during the interactions with microorganisms, but...
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Identification of NADPH Oxidase Genes Crucial for Rice Multiple Disease Resistance and Yield Traits
Reactive oxygen species (ROS) act as a group of signaling molecules in rice functioning in regulation of development and stress responses....
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The role of NADPH oxidase 1 in alcohol-induced oxidative stress injury of intestinal epithelial cells
Alcohol-mediated reactive oxygen species (ROS) play a vital role in intestinal barrier injury. However, the mechanism of ROS accumulation in...
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Characterization of the binding of cytosolic phospholipase A2 alpha and NOX2 NADPH oxidase in mouse macrophages
BackgroundPrevious studies have demonstrated that cytosolic phospholipase A 2 α (cPLA 2 α) is required for NOX2 NADPH oxidase activation in human and...
