Get major-city sophistication in a location that is one of the world’s natural wonders. Obviously a hub for those seeking the Rocky Mountain ski slopes, Denver is also home to four major sports teams, major museums and a wide variety of neighbourhoods that make the city a destination in its own right.

Although its highly residential quality and proximity to Denver make Aurora seem like simply a suburb of the larger metropolis, this bustling city has a flavor all its own. With seven golf courses, a reservoir beach, hiking trails and a multi-use Sports Park, the city is a major hub of athletics and hometown to numerous pro football, basketball, hockey and soccer players and coaches. Aurora's emerging arts scene brings forth vibrant theater and visual arts to liven up the city.

Prospectors discovered gold when they founded Breckenridge in 1859. Today, this historic mining town is fostering a whole new set of riches: world-class skiing, an expansive trail network, festivals and events, a vibrant Main Street and plenty of ways to unwind. In Breckenridge, all four seasons are packed with the best of the outdoors, the indoors, and everything in between.

Venture into the unspoiled beauty of 7,000-foot Rocky Mountain vistas, marvel at the contrast of ancient native culture mixed with modern arts, feast on legendary cuisine and relax in rustic sophistication. A visit to Santa Fe, Travel & Leisure's #1 Cultural Getaway, feels a lot like a visit to Europe. The Spanish Colonial charm of this historic destination has been enchanting travellers for over 400 years. And Santa Fe shows no signs of slowing down.

Moab attracts all types of outdoor adventurers. Mountain biking is huge here—experts claim it has some of the best trails in the world—as are rock-climbing and hiking. And the setting, with its gorgeous red rocks, can't be beat.

A crossroads for historians, sportsmen, architects, artists and gourmands, Colorado Springs offers a delightful mix of Western charms. Sunny skies and crisp mountain air make it a perfect place for a golf outing, extreme sports or a picnic in one of the many, many well-maintained parks.

Flanked by lakes, mountains and intriguing rock formations, Grand Junction offers a different side of Colorado. Mild weather year-round creates an agricultural oasis for 22 different wineries. Mountain bike along winding desert trails, wine and dine next to majestic rivers, and peruse a variety of shops, galleries and boutiques. For breathtaking natural beauty, don’t miss Grand Mesa National Forest and Colorado National Monument’s 23-mile stretch of scenic overlooks.

Despite its name, Winter Park is really a destination for all seasons. The Winter Park resort draws skiers and snowboarders in the winter and mountain bikers in the summer. Trailblazers may take to the woods on snowmobiles or cross-country skis in the snowy months, but when the sun comes out those same trails are perfect for hiking and the water is high for rafting. Spring wildflowers, summer wildlife, fall colors and crystalline winters make Winter Park a true natural wonder all year long.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

As North America’s northernmost large metropolis, Edmonton is a fascinating study in contrasts — a vibrant urban centre in the heart of the wilderness. It’s a city that’s never been afraid to do things a little differently, as visitors discover through close encounters with free-roaming bison, a shopping mall that spans more than 48 city blocks, and a dynamic arts and culture scene that embraces more than 40 annual festivals, including the continent’s biggest and wildest Fringe Theatre Festival.

What happens when a "gassy" Englishman rows into town feeling thirsty? A pub is born. And from that a city—in this case Vancouver. Though the pubs are plentiful, food and drink aren’t the only things to take in during your trip. In its 150 years, Vancouver has grown into a cosmopolitan city nestled in the great outdoors. Enjoy the snow-capped mountains, waterfront forests, cityside beaches, Olympic history and the world’s highest suspension bridge. Hipsters welcome. (Don’t worry, they don’t bite.)

Montreal, c’est si bon! This French-speaking city is considered the cultural capital of Canada, and is a cosmopolitan celebration of Québécois style. A horse-drawn carriage ride around the cobblestone streets and grand buildings of Vieux-Montréal will give you a taste of European flavour. The Basilique Notre-Dame is a confection of stained glass, and the Plateau Mont-Royal district will delight you with its quaint boutiques and cafés. Dig in to a massive plate of poutine to fuel up for a tour of the epic Olympic Park.

The first time you go to New York, go ahead and be a sight-seer—everyone should visit the Statue of Liberty, the Met, Times Square, etc. But on a return trip, pick a neighbourhood and go deep. You’ll find hole-in-the-wall bars, great delis, quirky shops… exploring the non-touristy side of New York is an incredibly rewarding experience for a traveller.

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Ottawa is a compact, clean, cleverly planned centre of culture and politics. And it's an ideal choice for a weekend getaway. Start downtown at the architecturally stunning National Gallery of Canada, and don't miss the Canadian Nature Museum and the National Aviation Museum. Rideau Canal offers boating in the summer and ice-skating in the winter. Gatineau Park attracts cyclists and walkers, while Byward Market blends old and new Ottawa.

It's still one of the most British cities in North America, but there's more to Victoria than tearooms, antique shops and galleries (though there are plenty of those). Driven by the younger generation, the city has sprouted a collection of cool shops, authentic coffee bars and unique restaurants. It also has more cycling routes than any other Canadian city, providing a great way to explore the picturesque location (and avoid an afternoon of antique shopping).