Moab attracts all types of outdoor adventurers. Mountain biking is huge here—experts claim it has some of the best trails in the world—as are rock-climbing and hiking. And the setting, with its gorgeous red rocks, can't be beat.

Get major-city sophistication in a location that is one of the world’s natural wonders. Obviously a hub for those seeking the Rocky Mountain ski slopes, Denver is also home to four major sports teams, major museums and a wide variety of neighbourhoods that make the city a destination in its own right.

Venture into the unspoiled beauty of 7,000-foot Rocky Mountain vistas, marvel at the contrast of ancient native culture mixed with modern arts, feast on legendary cuisine and relax in rustic sophistication. A visit to Santa Fe, Travel & Leisure's #1 Cultural Getaway, feels a lot like a visit to Europe. The Spanish Colonial charm of this historic destination has been enchanting travellers for over 400 years. And Santa Fe shows no signs of slowing down.

With its rich cultural heritage from Native American and Spanish settlers, New Mexico has been both a Spanish colony and a Mexican colony, and still retains a strong individual identity within the United States. The landscape is breathtaking, the food incredible, and there is a thriving cultural scene, all of which makes New Mexico, and Santa Fe in particular, a great place and a family friendly holiday destination all year round.

With the Rocky Mountains and the famous Route 66 both passing through New Mexico, there are some obvious attractions to explore, and that's before you consider taking a day out to explore Roswell to look for UFO wreckage, or Los Alamos (where the atomic bomb was developed). The other major towns are the capital Albuquerque (home of an amazing hot air balloon festival), and the tourist hotspot Santa Fe up in the mountains. Santa Fe is an artistic centre, and there are many museums and galleries to explore, as does nearby Taos. Santa Fe has a lot to recommend it, there's the art scene, the scenic beauty of this city at 7,000 feet, and then there's the diversity of the arts, food and people themselves. It has a very small, compact downtown, which is easy for a family to walk around, and a host of film festivals, art festivals, wine festivals and other special events throughout the year.

Whether you're into history, culture or outdoor adventures, or just in need of some new and unique scenery, Albuquerque offers exciting attractions for all ages and interests, at any time of year. In the historic section of Old Town, ancient Indian and Spanish cultures come to life through old churches, quaint shops and piazzas, winding brick paths and adobe benches. Browsers can spend a day making their way through the more than 100 shops, boutiques and galleries that sell Southwestern goods as well as unique products from around the world. During the winter holiday season, Old Town is adorned with small lighted candles and thousands come to stroll through the streets, listen to live music and celebrate -- it's truly a sight to see. But the history doesn't stop there. The Indian Pueblo Cultural Center and the Petroglyph National Monument offer a glimpse of old Indian customs and art. Families will find plenty to do at the Albuquerque Biological Park, which features a zoo, aquarium and botanic garden. Outdoor types will find ample opportunities for hiking, cycling and golf. After working up an appetite, head to one of the many fine restaurants that serve up a choice of hot or even hotter New Mexican cuisine. To top it all off, take a ride on the Sandia Peak Aerial Tramway for spectacular views of all this vibrant city has to offer.

North America's biggest and most popular ski resort, Vail is an alpine village in the heart of the Rocky Mountains. Long a favourite of serious skiers and jet setting celebrities, Vail now also draws a younger, hipper snowboarding crowd. Skiing is king at Vail Mountain and the Blue Sky Basin, but the area's vast splendor is perfect for hiking, biking, snowmobiling or scenery-gazing at any time of the year.

A crossroads for historians, sportsmen, architects, artists and gourmands, Colorado Springs offers a delightful mix of Western charms. Sunny skies and crisp mountain air make it a perfect place for a golf outing, extreme sports or a picnic in one of the many, many well-maintained parks.

Formerly a lawless frontier town, known for wild saloons and vigilante justice, Laramie is now a quiet college town, popular with outdoor enthusiasts as well as history buffs. Over twenty sites in and around Laramie are on the National Register of Historic Places, including the Wyoming Territorial Prison, which once held Butch Cassidy. The town is conveniently located between the Laramie Range and the Medicine Bow Mountains, making the area a paradise for mountain bikers, climbers and campers.

We won't lie: Niagara Falls is uber-touristy. There are wax museums and a Ripley's Believe It or Not Museum, and if it's a fast-food chain, you can probably find it here. But even the most jaded hipster shouldn't pass up a chance to visit this town, because the Falls themselves are spectacular.

The first time you go to New York, go ahead and be a sight-seer—everyone should visit the Statue of Liberty, the Met, Times Square, etc. But on a return trip, pick a neighbourhood and go deep. You’ll find hole-in-the-wall bars, great delis, quirky shops… exploring the non-touristy side of New York is an incredibly rewarding experience for a traveller.

Montreal, c’est si bon! This French-speaking city is considered the cultural capital of Canada, and is a cosmopolitan celebration of Québécois style. A horse-drawn carriage ride around the cobblestone streets and grand buildings of Vieux-Montréal will give you a taste of European flavour. The Basilique Notre-Dame is a confection of stained glass, and the Plateau Mont-Royal district will delight you with its quaint boutiques and cafés. Dig in to a massive plate of poutine to fuel up for a tour of the epic Olympic Park.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

What happens when a "gassy" Englishman rows into town feeling thirsty? A pub is born. And from that a city—in this case Vancouver. Though the pubs are plentiful, food and drink aren’t the only things to take in during your trip. In its 150 years, Vancouver has grown into a cosmopolitan city nestled in the great outdoors. Enjoy the snow-capped mountains, waterfront forests, cityside beaches, Olympic history and the world’s highest suspension bridge. Hipsters welcome. (Don’t worry, they don’t bite.)

Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

As North America’s northernmost large metropolis, Edmonton is a fascinating study in contrasts — a vibrant urban centre in the heart of the wilderness. It’s a city that’s never been afraid to do things a little differently, as visitors discover through close encounters with free-roaming bison, a shopping mall that spans more than 48 city blocks, and a dynamic arts and culture scene that embraces more than 40 annual festivals, including the continent’s biggest and wildest Fringe Theatre Festival.

Ottawa is a compact, clean, cleverly planned centre of culture and politics. And it's an ideal choice for a weekend getaway. Start downtown at the architecturally stunning National Gallery of Canada, and don't miss the Canadian Nature Museum and the National Aviation Museum. Rideau Canal offers boating in the summer and ice-skating in the winter. Gatineau Park attracts cyclists and walkers, while Byward Market blends old and new Ottawa.

Soaring mountains, jewel-coloured lakes and pristine wilderness await you in Canada’s first National Park. The irresistible beauty of the landscape invites travellers to immerse themselves in the outdoors all year round — whether hiking through untouched forests and paddling the turquoise lakes in summertime, or skiing the slopes and soaking in the steamy hot springs during the winter. Travellers also enjoy the warm hospitality of Banff or Lake Louise, the region’s charming mountain townships.