Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. See the Portfolio User Guide.

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year PCORI approved the research study or project for funding. View Glossary
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Displaying 1 - 25 of 187 results

Project Title
Project Status
Funding Type

Comparative Effectiveness of ICD Versus Non-ICD Therapy in Contemporary Heart Failure Patients With a Low Risk for Arrhythmic Death (CONTEMP-ICD)

University of Rochester
| New York
Ilan Goldenberg, M.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Balanced Subgroup Discovery: Who Benefits Most From an Intervention?

Wake Forest University
| North Carolina
Joseph Rigdon, B.S., M.S., Ph.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Boston Hypertension Equity Alliance in Treatment: Comparing System-Based Approaches to Hypertension Control in the Safety-Net Setting

Boston Medical Center Corporation
| Massachusetts
Michael Fischer, M.D., MS
Project Status:
Awarded; In progress
Funding Type:
Research

Improving High Blood Pressure in Older Adults Living with Multiple Chronic Diseases - The SMBP Study

The University of Iowa College of Pharmacy
| Iowa
Korey Kennelty, M.S., Ph.D., Phrm.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Achieving Equity: Inclusion of Adults with Congenital Heart Disease (CHD) Living with Neurodevelopmental Disorders (NDDs) in Patient Centered Outcomes Research

Children's Research Institute
| District of Columbia
Anitha John, M.D., Ph.D.
Project Status:
Awarded; In progress
Funding Type:
Research

Delay AvoIding Primary Evaluation for ThRombectomy of Acute StrokE Patients with Large Vessel OCclusion in the Angiography SuiTe (DIRECT) Trial

University of Iowa
| Iowa
Santiago Ortega-Gutierrez, MD
Project Status:
Awarded; Contract pending
Funding Type:
Research

The SCOPE Trial: Sleep, Cognition, and Pain Bundle Versus Enhanced Recovery After Surgery-Cardiac for Postoperative Delirium

Beth Israel Deaconess Medical Center
| Massachusetts
Balachundhar Subramaniam, M.D., MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Causal Mediation Methods for Cluster-Randomized Pragmatic and Implementation Trials

Yale University
| Connecticut
Fan Li, Ph.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

Delivering HOPE (Helping Women Optimize Prenatal Equity)

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, M.A., MBA, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Bayesian Machine Learning for Causal Inference in Electronic Health Record Data with Missing Covariates

Brown University School of Public Health
| Rhode Island
Arman Oganisian, Ph.D.
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

Improving Heterogeneous Effect Estimation by Integration of Experimental and Observational Studies

Vanderbilt University Medical Center
| Tennessee
Amir Asiaeetaheri, Ph.D.
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research, Research Conducted Using PCORnet®

Implementation and Interaction of Clinician and Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction

University of Colorado Denver
| Colorado
Larry Allen, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Comparative Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy

The Ohio State University
| Ohio
Maged Costantine, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Remote Hypertension Tracking Help and Management to Reduce Disparities in Black Patients (RHYTHM-B)

Wake Forest University Health Sciences
| North Carolina
Yhenneko Taylor, Ph.D., Mstat
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Improving Outcomes for Patients with Multiple Chronic Conditions Using ECHO

University of New Mexico Health Sciences Center
| New Mexico
Sanjeev Arora, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Revascularization Choices Among Under-Represented Groups Evaluation (The RECHARGE Program)

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Mario Gaudino, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research, Research Conducted Using PCORnet®

Improving Cardiovascular Health in Polycystic Ovary Syndrome

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Anuja Dokras, M.D., Ph.D., MHCI
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research

Implementing Doula Care in Medicaid to Advance Racial Equity in Severe Maternal Morbidity

AcademyHealth
| District of Columbia
Susan Kennedy, MSW, MPP
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Does Telehealth Help Mothers Receive Timely Care after Giving Birth?

University of Arkansas for Medical Sciences
| Arkansas
Jennifer Callaghan-Koru, PhD, MBA
Project Status:
In progress; Recruiting
Funding Type:
Research

Comparing Two Ways to Improve Health Outcomes for Women after Giving Birth -- The IMPACT Study

University of Texas Southwestern Medical Center
| Texas
Elaine Duryea, M.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Developing New Methods for Predicting Health Outcomes Using Electronic Health Record Data

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Funding Type:
Research, Research Conducted Using PCORnet®

Developing New Methods to Study Secure Electronic Messages between Doctors and Patients -- The ECLIPPSE-CER Study

The Regents of the University of California, San Francisco
| California
Dean Schillinger, M.D.
Project Status:
Awarded; Contract pending
Funding Type:
Research

PRESSURE POINTS: A Multilevel Team, Pragmatic Trial to Address Blood Pressure Control and Social Determinants of Health (SDOH)

Yale University
| Connecticut
Erica Spatz, M.D., MHS
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Comparing Ways to Support Patients with Home Blood Pressure Monitoring -- The CHARMED Study

The Regents of the University of California, San Francisco
| California
Urmimala Sarkar, MD, MPH
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

Prehabilitation and Rehabilitation in PAD: A Randomized Exercise Intervention Trial (PREPARE-IT)

Palo Alto Veterans Institute for Research
| California
Jonathan Myers, Ph.D.
Project Status:
In progress; Not yet recruiting
Funding Type:
Research

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