In June 2024, the Board approved Gavi’s new five-year strategy, ‘Gavi 6.0’. Gavi 6.0 sets out the Alliance’s vision, mission, strategic goals, objectives, operating principles and critical enablers for Gavi’s sixth strategic period (2026–2030).
Leaving no one behind with immunisation
To save lives and protect people’s health by increasing equitable and sustainable use of vaccines
| Under-five child mortality reduction | Future deaths averted (including disaggregated for climate-sensitive diseases) | Future DALYs averted |
| Reduction in zero-dose children | Children immunised | Economic benefits unlocked |
Gavi 6.0’s strategic framework includes ten principles, intended to define the Vaccine Alliance’s characteristics, its business model and its aspirations – such as being country-led and sustainable as well as community-owned and inclusive, making zero-dose and missed communities its first priority, being gender-focused, or being innovative, collaborative and accountable:
Country-led, sustainable
Country-led, sustainable
Bolster country leadership to sustainably finance and deliver immunisation.
This principle signals the importance of country-led approaches in Gavi 6.0, including in priority setting for immunisation.
Community-owned, inclusive
Community-owned, inclusive
Engage communities and civil society organisations in planning, implementation and oversight of immunisation.
This principle signals the importance of community engagement in Gavi 6.0, including in priority setting for immunisation.
Zero-dose and missed communities,
first priority
Zero-dose and missed communities, first priority
Prioritise children missing out on vaccination, including among migrants, displaced and other vulnerable populations.
This principle signals Gavi’s core focus on the equity agenda, further described under strategic goal 1. It will remain Gavi’s core programmatic priority.
Gender-focused
Gender-focused
Identify and address gender-related barriers to promote immunisation equity.
Building on the learnings from Gavi 5.1, the Alliance will continuously enhance its approach to gender-responsive programming and gender equity.
Differentiated, fragility-responsive
Differentiated, fragility-responsive
Target and tailor support to regional, national and subnational needs, including fragile, conflict and humanitarian contexts.
The Alliance will further differentiate interventions – prioritising, targeting and tailoring to specific national and sub-national contexts through each phase of the transition out of Gavi support.
Integrated
Integrated
Strengthen integration of immunisation and primary health care to reach missed communities in support of Universal Health Coverage.
This principle speaks to the importance of integrated approaches for the Alliance’s equity agenda; and Gavi’s contribution to more resilient, equitable, people-centred and sustainable health systems in support of Universal Health Coverage and in alignment with the Lusaka Agenda.
Adaptive, resilient
Adaptive, resilient
Help countries leverage immunisation to address the challenges of global health security, antimicrobial resistance and other major global issues.
The Alliance will continue to: (a) support countries to introduce and scale up vaccines to prevent outbreaks, and to procure diagnostics to detect and contain them; (b) ensure vaccine availability at the onset of outbreaks; and (c) foster a coalition of partners to prepare for and coordinate outbreak response activities.
Climate-sensitive
Climate-sensitive
Support countries to adapt to the consequences of climate change and mitigate the carbon footprint of the Alliance.
This principle was newly added in Gavi 6.0. The Alliance will mainstream climate change considerations into its investments and engagement across the four strategic goals.
Innovative
Innovative
Identify and scale up innovative products, practices and services to support Gavi’s goals.
Gavi will continue to support new products, practices and services to enhance immunisation efficiency and effectiveness in alignment with Gavi’s mission and country needs.
Collaborative, accountable
Collaborative, accountable
Accelerate purposeful partnerships with regional and global health institutions to collectively and efficiently respond to countries’ needs.
Gavi 6.0 will see an increased role of regional institutions like Africa CDC and the African Union Commission; and will continue to accelerate greater, purposeful collaboration with Global Health Initiatives both within and beyond the immunisation sector, in line with the Lusaka Agenda.
Gavi 6.0, the Alliance’s 2021–2025 strategy has four goals, each of them supporting the Alliance’s mission to save lives and protect people’s health by increasing equitable and sustainable use of vaccines. The four goals are:
Gavi 6.0 will provide access to the widest, most innovative portfolio of critical life-saving vaccines ever. The Alliance will support countries vaccinate >500 million more children and adolescents, saving 8-9 million more lives, including 1.5 million through the HPV vaccine.
Gavi will prioritise three main objectives for the introduction and scaling up of vaccines:
Increasing equity in immunisation delivery will remain central to Gavi’s next strategy, which aims to contribute to the Immunisation Agenda 2030’s ambition to reduce the number of ‘zero-dose’ children by 50%.
To achieve this, Gavi will focus on three main objectives for strengthening health systems:
Gavi does not just help countries expand their national immunisation programmes. It also aims to make immunisation sustainable both financially and programmatically, ensuring countries can sustain their immunisation programmes after Gavi support ends.
To support the sustainability of immunisation programmes, the Alliance will prioritise three main objectives:
The Alliance market shaping model will remain central in 6.0 to foster a sustainable, competitive supplier base, healthy demand, and an environment that encourages innovation.
The Alliance will prioritise three main objectives to ensure healthy markets:
Secure long-term predictable funding for Gavi programmes
In line with Gavi’s five-year funding cycles, long-term predictable funding is critical for the Alliance to deliver on its mission.
Deliver as one Alliance with strengthened accountability mechanisms
Gavi will further develop its approach to clearly delineate roles and responsibilities between Alliance partners based on their comparative advantages at global, regional and country levels; improve the culture, capacity and ways of working of the Alliance; and strengthen mutual accountability mechanisms to drive efficiency and performance.
Ensure global political commitment for immunisation and global health security
This enabler signals the importance of the Alliance’s engagement at global level to drive financial and non-financial support for the Alliance’s agenda, while promoting prevention and integration with primary health care.
Ensure simple, efficient and agile Gavi operating model
This new enabler reflects the anticipated streamlining of the Secretariat’s operating model in Gavi 6.0 to better meet the needs of countries. Key changes could include grounding Gavi funding to countries’ national strategies; consolidating Gavi’s cash-based funding into a single envelope focusing on immunisation delivery outcomes; and reforming grant management.
Drive digitalisation (including artificial intelligence), improved data and evidence
This enabler reflects the relevance of new digital technologies and data to drive immunisation outcomes in Gavi 6.0, based on evidence-based decision making.
Leverage the private sector and development finance institutions,
including through innovative finance mechanisms
This enabler builds on Gavi’s 20-year track record of leveraging innovative finance to achieve the Alliance's goals. In Gavi 6.0, this will continue through the International Finance Facility for Immunisation (IFFIm); increased lending and financing with multilateral development banks; and significantly enhanced private sector resource mobilisation.
The design of Gavi 6.0 followed three main phases, each involving key touchpoints with the Gavi Board. Following the Board’s approval in June 2024, a final phase focuses on operationalising the new strategy:
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The design of Gavi 6.0 concluded in June 2024. This leaves 18 months to complete the execution of the Gavi 5.0/5.1 agenda; and prepare to implement the key shifts emerging from Gavi 6.0 from day one.
In late February 2024, Gavi convened a broad consultation in Togo, bringing together over 120 representatives from implementing country governments, civil society organisations, and core and expanded Alliance partners.
The event marked a significant milestone in the country-centric design process for Gavi 6.0 ahead of a Gavi Board retreat in April 2024.
The design of Gavi 6.0 started by exploring global trends and their implications for the future global health landscape. This enabled a vision to start taking shape for Gavi 6.0 that identified high-level opportunities for impact and enablers for success. These trends were then assessed based on available evidence, impact data and opinions collected during consultations with the global health community.
Phase 2 aimed to identify high-level options for each opportunity for impact and surface trade-offs, to support the Gavi Board in making strategic choices about Gavi’s priorities for the next strategic cycle. Assessment of different options was based on expected health impact and financial implications; key inputs emerged from:
At its retreat in April 2024, the Gavi Board discussed different strategic options and made trade-offs based on estimated health impact and financial implications (costs) – with the goal to design a strategy that would be ambitious for the Alliance, while still realistic in terms of resources needed to deliver on it. Based on the Board’s guidance, concrete strategic options were selected and brought together in the final Gavi 6.0 strategy; and summarised in a one-page framework and an accompanying narrative document. In June 2024, the Board reviewed and approved the Gavi 6.0 strategy and endorsed the proposed approach to operationalise Gavi 6.0.