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Immunohistochemistry of Brain Tissues
Immunohistochemistry (IHC) is the basis of histological or pathological analysis and is widely used to enable the detection and characterization of...
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High-Throughput Multiplex Immunohistochemistry of Glioma Organoids
The invasive capacity and progression of glioblastoma cells and neoplastic cells in other are dependent on interactions with the surrounding tumor...
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Enzymatic Immunohistochemistry
Immunohistochemistry (IHC) is a powerful laboratory technique that is widely used in a variety of settings, including clinical medicine and research....
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Cryosectioning and Immunohistochemistry Using Frozen Adult Murine Brain Neural Tissue
Cryopreservation and immunohistochemistry offer a comprehensive, robust, and simple methodology to investigate neural patterning and cellular...
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Immunohistochemistry and Immunocytochemistry Methods and Protocols
This volume provides a comprehensive reference guide for researchers to study the applications of labeled antibodies. Chapters guide reader through...
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Immunohistochemistry for Cancer Stem Cell Detection: Principles and Methods
Cancer stem cells (CSCs) are rare immortal cells within tumors with capabilities of self-renewal, differentiation, and tumorigenicity. CSCs play a...
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Fluorescent Immunohistochemistry
Immunofluorescence is an important immunochemical technique that utilizes fluorescence-labeled antibodies to detect specific target antigens. It is...
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Scoring Systems for Immunohistochemistry in Urothelial Carcinoma
Immunohistochemistry is widely used in diagnostic and scientific analysis of urothelial carcinoma. Objective interpretation of staining results is...
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Identification of STAG2-Mutant Bladder Cancers by Immunohistochemistry
Bladder cancer is the fifth most common cancer in the United States. Most bladder cancers are early-stage lesions confined to the mucosa or submucosa...
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Immunohistochemistry for VM Markers
Vasculogenic mimicry (VM) is the biological process by which aggressive cancer cells are able to organize themselves—independently from endothelial...
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Immunohistochemistry and In Vivo Neural Imaging in A. mexicanus
The small size and transparency of many teleost brains provide the unique opportunity to image from the entire brain in an individual animal. The...
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Multiplex immunohistochemistry defines two cholesterol metabolism patterns predicting immunotherapeutic outcomes in gastric cancer
BackgroundThe role of cholesterol metabolism in gastric cancer (GC) and its implications for tumor characteristics and immunotherapy response remain...
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Application of Immunohistochemistry in Papillary Thyroid Carcinoma
Immunohistochemistry (IHC) is an economic and precise method to localize the presence of specific protein at cellular level in tissue. Although many...
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Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry
BackgroundRisk-assessment of endometrial cancer (EC) is based on clinicopathological factors and molecular subgroup. It is unclear whether adding...
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Immunohistochemistry and Molecular Biology of Cancer
In the era of targeted cancer therapy, immunohistochemistry (IHC) and gene alterations must be detected by pathologists for diagnostic, prognostic,...
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P16 immunohistochemistry is a sensitive and specific surrogate marker for CDKN2A homozygous deletion in gliomas
Molecular characterization of gliomas has uncovered genomic signatures with significant impact on tumor diagnosis and prognostication. CDKN2A is a...
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Primary Antibody Selection and Blocking Techniques for Immunohistochemistry
Immunohistochemical procedures are complex, multiparameter assays that must take into account many factors during protocol development. The overall...
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Immunohistochemistry, Quality Control, and Principles of Validation in the Central Nervous System
The conventional hematoxylin and eosin stain (H&E) is vital for the histological diagnosis but the role of immunohistochemistry (IHC) in the central...
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Immunotherapy Guided by Immunohistochemistry PD-L1 Testing for Patients with NSCLC: A Microsimulation Model-Based Effectiveness and Cost-Effectiveness Analysis
BackgroundOn the basis of immunohistochemistry PD-L1 testing results, patients with advanced non-small cell lung cancer (NSCLC) are treated...
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Multiplex Fluorescent Immunohistochemistry for Preservation of Tumor Microenvironment Architecture and Spatial Relationship of Cells in Tumor Tissues
The tumor microenvironment (TME), composed of immune cells, antigens, and local soluble factors, is integral to cancer development and progression....
