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An oral inulin allergen gel restores the microbiota of allergic mice and suppresses undesired immune responses to achieve allergen-specific oral tolerance, effectively overcoming food allergy.
A high-throughput screen of substances generally recognized as safe identifies species-specific materials that stabilize live microbial therapeutics as powders, making them robust to pharmaceutical manufacturing workflows.
Hydrogel force sensors directly bioprinted into embryonic tissues quantify the forces driving tissue remodelling and reveal the existence of mechanisms that counteract tissue morphogenesis.
Patient-derived pancreatic cancer organoids grown in engineered matrices acquire chemoresistance due to the increased expression of drug efflux transporters, promoted by CD44 receptor interactions with hyaluronan in the stiffer tumoural matrix.
A method is introduced to quantify short-range order in multicomponent alloys using atom probe tomography, which enables further understanding and materials design related to atomic-scale solute engineering.
The voltage penalty driving water dissociation at high current density is a challenge for bipolar-membrane-based energy devices. Materials descriptors such as electrical conductivity, microscopic surface area and surface-hydroxyl coverage are now shown to control water dissociation kinetics in these membranes.
Extreme confinement of water and ions within nanofluidic channels gives rise to unusual transport phenomena. Here the authors investigate how electronic properties of carbon nanotube porins influence the transport efficiency of water and ions.
The development of n-type organic semiconductors (OSCs) has been held back due to stability issues. Here the authors report that vitamin C improves both the performance and stability of n-type OSCs and devices.
Lipid bilayers under the influence of electric fields, similar to those across cell membranes, act as moderators of shear force between solid surfaces, presenting a new route to tuning interfacial properties across thin films.
The emergence of moiré superlattices in twisted two-dimensional halide perovskites has been reported, revealing the emergence of localized bright excitons with enhanced emissions and trapped charge carriers.
Current transfer printing technologies enable versatile flexible devices but challenges remain. Here the authors report a facile, versatile and damage-free dry transfer printing strategy based on stress control of the deposited thin films.
Heat in electronic devices is normally dissipated via cooling. Here the authors engineer the thermal dynamics of the Mott transition and dynamical thermal interactions with the substrate to enable neuromorphic computing in a NbOx-based device.
Tracking local material structure at picosecond timescales is realized using XFEL facilities. This pair distribution function measurement tracks the redevelopment of structural order through a non-equilibrium transition.
Interstitial oxygen conductors have the potential to enable efficient oxygen-ion transport at lower temperatures. An approach combining physically motivated structure and property descriptors, ab initio simulations and experiments is now proposed for the discovery of fast interstitial oxygen conductors.
Biomarkers in biofluids are widely used for medical diagnosis, but their use is limited by accessibility. Here the authors present a stretchable wearable sensor allowing in situ detection of solid-state biomarkers on human skin, hence avoiding biofluid acquisition.
MXenes with borate polyanion terminations are synthesized using a flux-assisted eutectic molten etching approach. These triatomic-layer terminations empower MXenes with considerably improved charge transport and charge storage capabilities.
Index-matched fluorescent particles provide a system that directly visualizes ionic crystallization using confocal microscopy, and offers insight into the structure, nucleation and growth of ionic solids.
Scanning tunnelling microscopy of doped RuCl3 shows distinct charge orderings at the lower and upper Hubbard bands, which can be attributed to a correlation-driven honeycomb hole crystal composed of hole-rich Ru sites and a rotational-symmetry-breaking paired electron crystal composed of electron-rich Ru–Ru bonds.
The authors investigate the origins of chirality transfer across length scales, quantitatively demonstrating how chirality propagates from the molecular to liquid crystal level in filamentous virus systems.
Here, the authors observe that in thin films of antiferroelectric PbZrO3, substrate clamping enhances the electromechanical response, with expansion purely in the out-of-plane direction, achieving 1.7% strain for 100-nm-thick films.