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Deciphering Protein Conversations: A Proteomic Exploration of protein-protein Interactions

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Closed
Proteins, the versatile workhorses of the cell, perform crucial roles vital for life. They act as enzymes, driving biochemical reactions; offer structural support to cells; engage in cellular signaling; and participate in various cellular functions, from energy production to maintaining homeostatic balance. However, their true power emerges when they interact with each other. Proteins rarely work in isolation and expand their capabilities by interacting with other proteins. These protein-protein interactions (PPIs) expand their functional repertoire, which can mediate complex functions and regulation of cellular metabolism beyond their normal individual capability. However, deciphering this complex web of interactions is a huge methodological challenge, for experimental biologists and proteome-informaticians. Understanding how PPIs amplify the capabilities of individual proteins and entire cellular systems is a fascinating puzzle. Unraveling how proteins orchestrate the complex biological systems and unearth the secrets of these interactions is the key to understanding biological functions, which are tightly regulated during development and disease. JPP encourages scientists and research groups to contribute to the special issue on “Protein-protein interactions”. JPP, an official journal of the Proteomics Society of India (PSI) is convening this call for submission of Original research articles, reviews, commentaries etc. in order to highlight the latest development in this aspect of proteomics research.

Editors

  • Dr. Amit Kumar Yadav Dr. Amit Kumar Yadav  &

    Dr. Amit Kumar Yadav

    Dr. Amit Kumar Yadav works at THSTI as Principal Scientist-II. Dr. Yadav obtained his Ph.D. in 2013 in Biotechnology (Computational Biology) from IGIB

  • Dr. Trayambak Basak Dr. Trayambak Basak

    Dr. Trayambak Basak

    Dr. Trayambak Basak has been working as an Assistant Professor at the School of Biosciences and Bioengineering (SBB), IIT-MANDI, Himachal Pradesh since October 2019. He completed his Ph.D on plasma proteomics and metabolomics analyses of coronary artery disease patients, from the CSIR-Institute of Genomics and Integrative Biology, New Delhi in 2015.

Articles (10 in this collection)