A magnet for skiers and hikers, these dramatic peaks – including the iconic Matterhorn – range from 3,000 to 15,000 feet and spread across three-fifths of the country. Abundant glaciers, scenic valleys and gorgeous alpine lakes add to the region's visual appeal. The Glacier Express train travels the 7.5-hour route through the Swiss Alps from Zermatt to St. Moritz, passing through fairy-tale villages and over 291 bridges along the way.

Famed for winter skiing and summer hiking and climbing opportunities, the Dolomites are a section of the Alps in northeastern Italy, running roughly from Pieve di Cadore in the east to the Adige River in the west. Marmolada, just east of Trento, is the highest peak, at nearly 11,000 feet. The dramatic and craggy mountains are famed for their unique colors, which are the result of their partial formations as undersea coral colonies before being pushed upward millions of years ago.

Once a vital part of a mighty sea power, Positano is today a sophisticated resort on the central Amalfi Coast. Moorish-style architecture rises up steep slopes that gaze out on the Sirenuse Islands. Smart boutiques, selling fashions for visitors to display on Grand Beach, abound in the village. And it’s a great base for exploring the area—you can easily travel by boat to Capri, Ischia and the Grotta dello Smeraldo cave.

U.S. citizens still need to jump through a few hoops to visit Cuba, but as visitors from around the world know, this island offers some amazing opportunities for cultural exchange. Havana is a mix of old-world architecture and of-the-moment culture. Head out of the capital city to the small town of Trinidad to see more Spanish colonial architecture. It’s a UNESCO World Heritage Site and a fantastic home base for a visit to the Valley of the Sugar Mills, a pocket of land that formerly served as the centre of Cuba’s sugar industry.