Study on algorithm and application to radical input method and standardization of Nvshu
Authors: Tian, Wei | Wang, Jiangqing | Wang, Li | Cheng, Li | Cao, Jing
Article Type: Research Article
Abstract: As an ancient character of larruping fascination, Nvshu has aroused international scholars’ interest, and the research of Nvshu has been developed widely. However, the research of Nvshu mostly based on handwriting at present has been developed slowly. So informationization of Nvshu has stared us in the face. The standardization of Nvshu is researched in this paper. Based on research of standardization, according to the research of literacy psychology and fuzzy psychology, the relationship of character recognition of Nvshu and computer input method was illuminated, and the samples of the Nvshu by using the statistic method of clustering were analyzed, in …order to extract the common parts of the Nvshu characters to form the etymons, which were the basic of computer input method of Nvshu. Because of computer input method, Nvshu has entered the era of informationization. This input method is accurate, stable, easily study and easily operable. Meanwhile this input method would make outstanding contributions to the protection of ancient literature. Show more
Keywords: Nvshu character, radical input method, etymon
DOI: 10.3233/JIFS-169093
Citation: Journal of Intelligent & Fuzzy Systems, vol. 31, no. 5, pp. 2525-2531, 2016
An evolution model of risk preference influenced by extremists in large group emergency consensus process
Authors: Cao, Jing | Xu, Xuan-hua | Dai, Fei | Pan, Bin
Article Type: Research Article
Abstract: This study uses opinion dynamics to explore the influence of extremists in the consensus process of large group decision-making. When moderates are exposed to extremists, their risk preference will be affected. By using the opinion leader theory for reference, the influence model of extremists is constructed. To better study the influence of extremists, the similarity of risk preference between extremists and moderates is modeled to measure their similarity degree. From this model, for every moderate, the extremists are divided into two groups: homogeneous group and heterogeneous group. Finally, the risk preference evolution model is structured by considering that moderates change …their risk preference dynamically according to their initial preference, their attitude towards the homogeneous groups, and the heterogeneous groups. Finding from data analysis shows that moderates with high acceptance toward the influence of extremists are more likely to reach group consensus. It is also found that the preference trend of moderates with a certain degree of acceptance toward heterogeneous groups fluctuates with a ‘W’ shape. This study bridges the gap between opinion dynamics and group decision making. Meanwhile, the model inspires new explanations and new perspectives for the group consensus process. Show more
Keywords: Extremists, opinion dynamics, group emergency decision-making, group consensus, risk preference evolution
DOI: 10.3233/JIFS-201106
Citation: Journal of Intelligent & Fuzzy Systems, vol. 39, no. 5, pp. 7733-7746, 2020
Communication barrier-incorporated network modeling for interorganizational opinion formation in emergency events
Authors: Cao, Jing | Xu, Xuan-hua | Chen, Yudi | Ji, Wenying
Article Type: Research Article
Abstract: During and after an emergency event, multiple organizations with various specialties are involved in consensus decision-making to reduce the loss of lives and property in a timely manner. However, timely, high-consensus decision-making is challenging due to communication barriers between participating organizations. Thus, this study generalizes a conceptual communication network considering communication barriers by reviewing multiple historical emergencies and proposes a quantitative communication network model by integrating an opinion dynamics model and social network analysis (SNA). An illustrative example is provided by simulating two emergency decision-making scenarios to verify the proposed model. A case study of the 2013 Qingdao oil pipeline …explosion is presented to demonstrate the feasibility and applicability of the proposed model. The results of the case study indicate that the proposed model can accurately quantify the impact of communication barriers on the opinion formation time. This research provides a quantitative toolkit for understanding and improving decision-making performance in various emergencies. Show more
Keywords: Interorganizational communication network, communication barriers, opinion formation, emergency decision-making
DOI: 10.3233/JIFS-212102
Citation: Journal of Intelligent & Fuzzy Systems, vol. 43, no. 3, pp. 3709-3726, 2022
Volatilization behaviors of diesel oil from the soils
Authors: LI, Yu-ying | ZHENG, Xi-lai | LI, Bing | MA, Yu-xin | CAO, Jing-hua
Article Type: Research Article
Abstract: The volatilization of diesel oil, Shengli crude oil and 90# gasoline on glass surface of petri dishes were conducted at the ambient temperature of 25°C. Diesel oil evaporates in a power manner, where the loss of mass is approximately power with time. 90# gasoline evaporates in a logarithmic with time. Where as the volatilization of Shengli crude oil fit either the logarithmic or power equation after different time, and has similar R^2 . And the effects of soil type and diesel oil and water content on volatilization behavior in unsaturated soil were studied in this paper. Diesel oil and water …content in the soils play a large role in volatilization from soils. Appropriate water helps the wicking action but too much water stops it. The wicking action behaves differently in four different types of soils in the same volatilization experiment of 18% diesel oil content and air-dry condition. Show more
Keywords: volatilization, diesel oil, power curve
Citation: Journal of Environmental Sciences, vol. 16, no. 6, pp. 1033-1036, 2004
Greater Attenuation of Retinal Nerve Fiber Layer Thickness in Alzheimer's Disease Patients
Authors: Shi, Zhongyong | Wu, Yujie | Wang, Meijuan | Cao, Jing | Feng, Wei | Cheng, Yan | Li, Chunbo | Shen, Yuan
Article Type: Research Article
Abstract: Thinning of retinal nerve fiber layer (RNFL) may reflect neurodegeneration of the central nervous system, which has been reported as part of the neuropathogenesis of Alzheimer's disease (AD). Specifically, AD patients have thinner RNFL as compared to age-matched normal controls. However, whether reduction of RNFL over time can predict those at higher risk to develop cognitive deterioration remains unknown. We therefore set out a prospective clinical investigation to determine both the reduction of RNFL thickness and the deterioration of cognitive function over a period of 25 months in 78 participants (mean age 72.31 ± 3.98 years, 52% men). The participants …were categorized as stable participants whose cognitive status remained unchanged (n = 60) and converted participants whose cognitive status deteriorated, which was diagnosed by DSM-VI (for AD) and Petersen's definition (for mild cognitive impairment) (n = 18). Here we show for the first time that the converted participants had greater reduction of RNFL thickness than the stable participants. Specifically, the reduction in the thickness of the inferior quadrant RNFL in the converted participants was greater than that in stable participants [−11.0 ± 12.8 (mean ± standard deviation) μm versus 0.4 ± 15.7 μm, p = 0.009]. These data showed that greater reduction in the inferior quadrant of RNFL thickness might indicate a higher risk for the old adults to develop cognitive deterioration. These findings have established a system to embark on a larger scale study to further test whether changes in RNFL thickness can serve as a biomarker of AD. Show more
Keywords: Alzheimer's disease, cognitive function, mild cognitive impairment, retinal nerve fiber layer thickness
DOI: 10.3233/JAD-131898
Citation: Journal of Alzheimer's Disease, vol. 40, no. 2, pp. 277-283, 2014
Uncertain optimal control problem with the first hitting time objective and application to a portfolio selection model
Authors: Jin, Ting | Zhu, Yuanguo | Shu, Yadong | Cao, Jing | Yan, Hongyan | Jiang, Depeng
Article Type: Research Article
Abstract: This paper discusses an uncertain time optimal control problem by considering time efficiency, which is to optimize the objective function about the first hitting time subject to uncertain differential equations. According to the definition of the α-path, the uncertain time optimal control problem is transformed into an equivalent deterministic optimal control problem. Two kinds of time optimal control models are presented where optimistic value and reaching index are chosen as the optimality criteria, respectively. Applying the proposed uncertain optimal control model to a portfolio selection problem, we obtain the uncertainty distribution of the first hitting time (the investors’ first profit …time). Meanwhile, sufficient conditions of the optimal control strategy of such models are provided. Numerical simulations are provided which reveal the change for our optimal control strategy. Show more
Keywords: Uncertainty optimal control, first hitting time, portfolio selection, optimistic value, reaching index
DOI: 10.3233/JIFS-222041
Citation: Journal of Intelligent & Fuzzy Systems, vol. 44, no. 2, pp. 1585-1599, 2023
The Utilization of Retinal Nerve Fiber Layer Thickness to Predict Cognitive Deterioration
Authors: Shi, Zhongyong | Zhu, Yingbo | Wang, Meijuan | Wu, Yujie | Cao, Jing | Li, Chunbo | Xie, Zhongcong | Shen, Yuan
Article Type: Research Article
Abstract: Our previous studies have shown that longitudinal reduction in retinal nerve fiber layer (RNFL) thickness is associated with cognitive deterioration. However, whether the combination of longitudinal reduction in RNFL thickness with baseline episodic memory performance can better predict cognitive deterioration remains unknown. Therefore, we set out to re-analyze the data obtained from our previous studies with 78 elderly adults (mean age 74.4 ± 3.83 years, 48.7% male) in the community over a 25-month period. The participants were categorized as either stable participants whose cognitive status did not change (n = 60) or converted participants whose cognitive status deteriorated (n = 18). A …logistic regression analysis was applied to determine a conversion score for predicting the cognitive deterioration in the participants. We found that the area under the receiver operating characteristic curve (AUC) for the multivariable model was 0.854 (95% CI 0.762–0.947) using baseline story recall as a predictor, but the AUC increased to 0.915 (95% CI 0.849–0.981) with the addition of the longitudinal reduction of RNFL thickness in the inferior quadrant. The conversion score was significantly higher for the converted participants than the stable participants (0.59 ± 0.30 versus 0.12 ± 0.19, p < 0.001). Finally, the optimal cutoff value of the conversion score (0.134) was determined by the analysis of receiver operating characteristic curve, and this conversion score generated a sensitivity of 0.944 and a specificity of 0.767 in predicting the cognitive deterioration. These findings have established a system to perform a larger scale study to further test whether the longitudinal reduction in RNFL thickness could serve as a biomarker of Alzheimer’s disease. Show more
Keywords: Alzheimer’s disease, conversion score, mild cognitive impairment, predictive model, retinal nerve fiber layer thickness
DOI: 10.3233/JAD-150438
Citation: Journal of Alzheimer's Disease, vol. 49, no. 2, pp. 399-405, 2016
Bilateral Hippocampal Volume Mediated the Relationship Between Plasma BACE1 Concentration and Memory Function in the Early Stage of Alzheimer’s Disease: A Cross-Sectional Study
Authors: Yin, Wenwen | Wan, Ke | Zhu, Wenhao | Zhou, Xia | Tang, Yating | Zheng, Wenhui | Cao, Jing | Song, Yu | Zhao, Han | Zhu, Xiaoqun | Sun, Zhongwu
Article Type: Research Article
Abstract: Background: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) is a key enzyme in the formation of amyloid-β (Aβ) protein. Increasing evidence suggests that BACE1 concentration is a potential biomarker for Alzheimer’s disease (AD). Objective: To evaluate the correlations between plasma BACE1 concentration, cognition, and hippocampal volume at different stages of the AD continuum. Methods: Plasma BACE1 concentrations were measured in 32 patients with probable dementia due to AD (ADD), 48 patients with mild cognitive impairment (MCI) due to AD, and 40 cognitively unimpaired (CU) individuals. Memory function was evaluated using the auditory verbal learning test (AVLT), and voxel-based morphometry …was used to analyze bilateral hippocampal volumes. Correlation and mediation analyses were performed to investigate the associations between plasma BACE1 concentration, cognition, and hippocampal atrophy. Results: The MCI and ADD groups exhibited elevated BACE1 concentrations compared with the CU group after adjusting for age, sex, and apolipoprotein E (APOE ) genotype. Increased BACE1 concentration was found in AD continuum patients who were APOE ɛ4 carriers (p < 0.05). BACE1 concentration was negatively associated with the scores of the subitems of the AVLT and hippocampal volume (p < 0.05, false discovery rate correction) in the MCI group. Moreover, bilateral hippocampal volume mediated the relationship between BACE1 concentration and recognition in the MCI group. Conclusion: BACE1 expression increased in the AD continuum, and bilateral hippocampal volume mediated the effect of BACE1 concentration on memory function in patients with MCI. Research has indicated that the plasma BACE1 concentration might be a biomarker at the early stage of AD. Show more
Keywords: Alzheimer’s disease, β-secretase, BACE1, hippocampus, mild cognitive impairment
DOI: 10.3233/JAD-221174
Citation: Journal of Alzheimer's Disease, vol. 92, no. 3, pp. 1001-1013, 2023
The Hippocampal Subfield Volume Reduction and Plasma Biomarker Changes in Mild Cognitive Impairment and Alzheimer’s Disease
Authors: Cao, Jing | Tang, Yating | Chen, Shujian | Yu, Siqi | Wan, Ke | Yin, Wenwen | Zhen, Wenhui | Zhao, Wenming | Zhou, Xia | Zhu, Xiaoqun | Sun, Zhongwu
Article Type: Research Article
Abstract: Background: The hippocampus consists of histologically and functionally distinct subfields, which shows differential vulnerabilities to Alzheimer’s disease (AD)-associated pathological changes. Objective: To investigate the atrophy patterns of the main hippocampal subfields in patients with mild cognitive impairment (MCI) and AD and the relationships among the hippocampal subfield volumes, plasma biomarkers and cognitive performance. Methods: This cross-sectional study included 119 patients stratified into three categories: normal cognition (CN; N = 40), MCI (N = 39), and AD (N = 40). AD-related plasma biomarkers were measured, including amyloid-β (Aβ)42 , Aβ40 , Aβ42 /Aβ40 ratio, p-tau181, and p-tau217, and the hippocampal subfield volumes were calculated …using automated segmentation and volumetric procedures implemented in FreeSurfer. Results: The subiculum body, cornu ammonis (CA) 1-head, CA1-body, CA4-body, molecular_layer_HP-head, molecular_layer_HP-body, and GC-ML-DG-body volumes were smaller in the MCI group than in the CN group. The subiculum body and CA1-body volumes accurately distinguished MCI from CN (area under the curve [AUC] = 0.647–0.657). The subiculum-body, GC-ML-DG-body, CA4-body, and molecular_layer_HP-body volumes accurately distinguished AD from MCI (AUC = 0.822–0.833) and AD from CN (AUC = 0.903–0.905). The p-tau 217 level served as the best plasma indicator of AD and correlated with broader hippocampal subfield volumes. Moreover, mediation analysis demonstrated that the subiculum-body volume mediated the associations between the p-tau217 and p-tau181 levels, and the Montreal Cognitive Assessment and Auditory Verbal Learning Test recognition scores. Conclusions: Hippocampal subfields with distinctive atrophy patterns may mediate the effects of tau pathology on cognitive function. The subiculum-body may be the most clinically meaningful hippocampal subfield, which could be an effective target region for assessing disease progression. Show more
Keywords: Alzheimer’s disease, cognitive performance, hippocampal subfield volumes, mild cognitive impairment, plasma biomarkers
DOI: 10.3233/JAD-231114
Citation: Journal of Alzheimer's Disease, vol. 98, no. 3, pp. 907-923, 2024
Prevalence, Risk Factors, and Complaints Screening Tool Exploration of Subjective Cognitive Decline in a Large Cohort of the Chinese Population
Authors: Hao, Lixiao | Wang, Xiaoni | Zhang, Ling | Xing, Yue | Guo, Qihao | Hu, Xiaochen | Mu, Bin | Chen, Yili | Chen, Guanqun | Cao, Jing | Zhi, Xiaodong | Liu, Jiaojiao | Li, Xuanyu | Yang, Liu | Li, Jiachen | Du, Wenying | Sun, Yu | Wang, Ting | Liu, Zhen | Liu, Zheng | Zhao, Xuexue | Li, Hongyan | Yu, Yang | Wang, Xue | Jia, Jianguo | Han, Ying
Article Type: Research Article
Abstract: Background: Substantial studies have reported the prevalence and the affecting factors of subjective cognitive decline (SCD). The complaints screening scale has also been used for probing. However, little is known in China. Objective: To investigate the prevalence and risk factors of SCD, and explore an SCD complaints screening scale in China. Methods: Stratified cluster random sampling was conducted. 2,689 residents aged 60–80 years completed questionnaire 1. 814 residents were included for clinical and neuropsychological evaluations. Two standards were used to make the diagnosis of mild cognitive impairment (MCI) and SCD, and a preliminary screening rate comparison was carried out. Finally, …we assessed the risk factors of SCD and the correlation between the SCD-questionnaire 9 (SCD-Q9) and the Auditory Verbal Learning Test-Long Delay Free Recall (AVLT-LR). Results: 1) Standard 1 (ADNI2): the prevalence of SCD was 18.8% (95% CI = 14.7–22.9%) and zero conformed to six criteria (SCD plus). 2) Standard 2 (Jak/Bondi): the prevalence of SCD was 14.4% (95% CI = 10.7–18.1%). 3) Standard 1 had a relatively higher “false” positive rate, whereas Standard 2 had higher “false” negative rate. 4) Age, low education, fewer close friends, and daily drinking were independent risk factors for SCD progressing to MCI. 5) Total points of SCD-Q9 were negatively correlated to the value of AVLT-LR. Conclusions: The prevalence of SCD is high in the ShunYi District in Beijing, China. Age, low education, less social support, and daily drinking are independent risk factors. The brief SCD-Q9 can be used as a reference. Show more
Keywords: Alzheimer’s disease, prevalence, risk factors, SCD-Q9, subjective cognitive decline
DOI: 10.3233/JAD-170347
Citation: Journal of Alzheimer's Disease, vol. 60, no. 2, pp. 371-388, 2017