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Juliet I Mmerem, Chukwudi C Umenzekwe, Simon M Johnson, Asukwo E Onukak, Nneka M Chika-Igwenyi, Sunday K Chukwu, Chizaram A Onyeaghala, Jideofor J Ozougwu, Datonye Alasia, Odianosen Ehiakhamen, Henry M Nwankwo, Ogochukwu I Ezejiofor, Uche S Unigwe, Michael O Iroezindu, Mpox and Chickenpox Coinfection: Case Series From Southern Nigeria, The Journal of Infectious Diseases, Volume 229, Issue Supplement_2, 15 April 2024, Pages S260–S264, https://doi.org/10.1093/infdis/jiad556
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Abstract
We describe clinicoepidemiologic characteristics of mpox-chickenpox coinfection in Nigeria.
A retrospective cohort analysis was performed of confirmed mpox cases in Nigeria from January 2022 to March 2023. Mpox and chickenpox were confirmed by real-time polymerase chain reaction (RT-PCR).
Of 94 (60.0%) suspected cases, 56 had confirmed mpox, of whom 16 (28.6%) had chickenpox coinfection. The median age of confirmed mpox cases was 29 years (interquartile range, 20–37 years), 24 were men (60.7%), 6 (10.7%) were bisexual, and 5 (8.9%) died. Mpox-chickenpox–coinfected patients had more complications than mpox-monoinfected cases (56.3% vs 22.5%, P = .015).
The high frequency of mpox-chickenpox coinfection argues for accelerated access to mpox and chickenpox vaccines in Africa.