The BRAIN podcast is the official podcast of Brain and Brain Communications highlighting the rich and diverse neuroscience published in the journals.
Each episode features an interview with a journal author and can be enjoyed by a broad audience, including clinicians, researchers, students, neuroscientists, neurologists, neurosurgeons and psychiatrists.
Episodes
This episode features a discussion with the final author Dr Jun Li of the Brain article entitled: PAK2 is necessary for myelination in the peripheral nervous system. How are peripheral nerve cells myelinated and what proteins are invoved? Is there a difference between PAK1 and PAK2?
Listen for this and more in this exciting episode.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad413
This episode was co-hosted by Andreas Thermistocleous and David Michael, edited and produced by David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
This episode features a discussion with first author author Dr Stefanie Grabrucker of the Brain article entitled: Microbiota from Alzheimer’s patients induce deficits in cognition and hippocampal neurogenesis.
How does lifestyle and the environment affect cognition in Alzheimer's disease via the gut and what can we do about it? Listen for this and more in this exciting episode.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad303
This episode was co-hosted by Chaitra Sathyaprakash and Adam Handel, edited and produced by Chaitra and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
This episode features a discussion with senior author Dr Bénédicte Ballanger of the Brain article entitled: Noradrenergic alterations in Parkinson’s disease: a combined 11C-yohimbine PET/neuromelanin MRI study
Can this multi-modal study examining the role of Noradrenaline in Parkinson's disease offer insight into important neurotrasmitter pathophysiology and provide the basis for a non-dopamine therapeutic strategy?
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad338
This episode was co-hosted by Andreas Themistocleous and Michael David, edited and produced by Michael David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad296
This episode was co-hosted by Andreas Themistocleous and Michael David, edited and produced by Michael David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
Check out the full article on the Brain Communications website: https://doi.org/10.1093/braincomms/fcad218
This episode was co-hosted by Andreas Themistocleous and Debra Ehrlich, edited and produced by Michael David and Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad090
We also hear from our new podcast host, Dr Chaitra Sathyaprakash, who is a post-doctoral fellow at National Institute of Neuroscience, Kodaira, Tokyo, Japan- welcome to the team!
This episode was co-hosted by Adam Handel and Chaitra Sathyaprakash, edited and produced by Xin You Tai, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
In this episode we speak with Josef Parvizi, senior author of the article entitled: Multisite thalamic recordings to characterize seizure propagation in the human brain. This article explores the role of the thalamus in seizure propagation and how multi-site intracranial electrode recordings identify new and unexpected findings regarding which thalamic nuclei may have the earliest involvement in seizure propagation.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awad121
This episode was co-hosted by Debra Ehrlich and Andreas Thermistocleous, edited and produced by Xin You Tai and David Michael, co-produced by Antonia Johnston, original music by Ammar Al-Chalabi.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac119
This episode was co-hosted by Adam Handel and Darshan Pandya, edited and produced by Adam Handel and Xin You Tai; co-produced by Antonia Johnston; original music by Ammar Al-Chalabi.
In this episode we speak with Ted Price, senior author of the article entitled: RNA profiling of human dorsal root ganglia (DRG) reveals sex differences in mechanisms promoting neuropathic pain. This article explores exciting findings around differences in the DRG transcriptome which were only apparent when stratifying participants by sex and how these differences may inform mechanistic targets for neuropathic pain.
Check out the full article on the Brain website: https://doi.org/10.1093/brain/awac266.
This episode was co-hosted by Andreas Thermistocleous and Debra Ehrlich, edited and produced by Xin You Tai; co-produced by Antonia Johnston and David Michael; original music by Ammar Al-Chalabi.
In this episode we speak with Philip Insel, lead author of the article entitled: Tau positron emission tomography in preclinical Alzheimer’s disease. The article explores the utility of tau PET imaging in three independent, large cohorts of cognitively normal individuals with high levels of amyloid (on PET imaging). We discuss specific areas of the brain with high tau concentration and how this differs from the traditional Braak model from neuropathology data. Philip also details how tau PET imaging can play a role in clinical trials.
This episode was co-hosted, edited and produced by Xin You Tai; co-hosted by Adam Handel; co-produced by Joanne Bell and Sarosh Irani; original music by Ammar Al-Chalabi.
In this episode, we speak with Hideaki Nishihara and Britta Engelhardt, lead authors of the article entitled: Intrinsic blood–brain barrier dysfunction contributes to multiple sclerosis pathogenesis. This was a transcontinental recording with our guests dialing in from Japan and Europe. The article explores blood-brain barrier dysfunction as a pathogenic process of multiple sclerosis. The authors discuss the use of a novel in vitro model of the blood-brain barrier which was designed to capture the activity of adhesion molecules involved in leukocyte trafficking.
This episode was co-hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
In this episode, three guests joined us to discuss the article entitled: Gene variant effects across sodium channelopathies predict function and guide precision therapy. Professor Andreas Brunklaus (first author) and Professor Stephanie Schorge (senior author) discuss their fascinating data-driven approach to better understand how mutations in sodium channels affect function with potential for precision therapy. We were fortunate to also be joined by Professor Massimo Mantegazza, who provided additional expert opinion.
This episode was hosted, edited and produced by Xin You Tai; co-hosted by Professor Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
In this episode we are joined by Associate Professor Pavan Bhargava to discuss his review article entitled "The contribution of B cells to the cortical damage in multiple sclerosis".
This episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
Journal article
Contribution of B cells to cortical damage in multiple sclerosisThis episode was hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
The episode is hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
Professor Marsel Mesulam gives a masterclass in the clinico-pathological-neuroimaging analysis of primary progressive aphasias.
The episode is hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.
See also
The episode is hosted, edited and produced by Xin You Tai; co-hosted by Sarosh Irani; co-produced by Joanne Bell; original music by Ammar Al-Chalabi.