Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Las Vegas is the place to go for the best nightlife, gambling, live shows and dining in the U.S.  But there's plenty to do in Nevada for all types of travellers. The state boasts more than 100 beautiful golf courses, and water lovers can relax on the shores of Lake Tahoe. Set your sights on the mountainous landscape, perfect for hiking, or tour the famous Hoover Dam. World class resorts with top of the line spas are located throughout the state's major cities and tourist locales.

Anyplace can have an amazing pool and spa, but an amazing pool and spa in the middle of a gorgeous desert? That’s what you’ll find at Sedona’s resorts. If you do feel like taking a break from lounging poolside and sampling different kinds of massages, you'll find miles of trails for hiking, biking and horseback tours. Afterward, of course, you'll need another massage. It's the good kind of vicious cycle.

Ideally situated just south of Las Vegas and just west of Lake Mead and the Hoover Dam, Henderson may lack Sin City's flamboyance, but it makes up for it in activities. Golf any of eight championship courses throughout the year, sample delectable treats from Ethel M Chocolates as you explore the Botanical Cactus Garden, the world’s largest cactus collection, pay respects at the Henderson Veteran's Memorial Wall or take your binoculars to the Bird Viewing Preserve.

Its location just 60 miles from the southern rim of the Grand Canyon makes Williams a popular stop for visitors to the natural beauty of Arizona. The historic Grand Canyon Railway makes it southern stop here, ferrying hundreds of thousands of tourists every year to and from the Canyon on its hundred-year-old steam-powered line. In the more immediate surrounds, the Kaibab National Forest and the Bill Williams Mountain area provide ample opportunities for camping, hiking and adventure.

U.S. citizens still need to jump through a few hoops to visit Cuba, but as visitors from around the world know, this island offers some amazing opportunities for cultural exchange. Havana is a mix of old-world architecture and of-the-moment culture. Head out of the capital city to the small town of Trinidad to see more Spanish colonial architecture. It’s a UNESCO World Heritage Site and a fantastic home base for a visit to the Valley of the Sugar Mills, a pocket of land that formerly served as the centre of Cuba’s sugar industry.

Cuba's top beach destination sits on a 13-mile-long peninsula with powder soft sands lapped by waters of the Kawama Channel. Resort hotels teem along the shore that U.S. celebrities and gangsters, including Capone, discovered in the 1920s. Clubs and bars provide mojitos and merriment, after long days baking on the beach, golfing, diving or deep sea fishing. Rent a scooter or hop aboard an open-air tourist train or bus to see more of this stunning spot. Caves, keys and virgin forest add to the area's allure.

Cayo Coco, an island just north of mainland Cuba, has some of the world’s most gorgeous beaches—think superfine white sand and shallow, clear water. It’s popular with European travelers seeking a sunny escape at one of the island’s beach-side resorts. Snorkeling and diving are fantastic.

From volcanic landscapes to hidden waterfalls… active adventures to an energetic nightlife… a holiday on the Hawaiian Islands offers infinite experiences in one destination. Each of the six major islands – Kauai, Oahu, Molokai, Lanai, Maui, and the island of Hawaii – has its own distinct personality, but no matter which ones you choose, you’ll discover endless opportunities for adventure, dining, culture and relaxation.

Isla Mujeres offers a wide variety of tempting options for beach lovers, and is a relative bargain. Snorkel with tropical fish amid coral reefs, skim the blue waters by kayak or boat, or windsurf along the shores of soft, sandy beaches. On land, you can sunbathe, dine on seafood, dance to Latin rhythms, tour on a moped or belly up to the bar for fresh, delicious drinks.

Get the experience of visiting two island colonies in the same 37 square miles. Saint Maarten/Saint Martin's spicy marriage of Caribbean, French and Dutch cultures matches its physical diversity: the island is both urban and untamed, with rain forest-like landscapes, white beaches, and amazing caves and wildlife.

With nine bays and 36 beaches, Huatulco is ideal for anyone who loves the sun. It's not an overdeveloped resort town, but the hotels are comfortable—even luxurious. Ecotourism is gaining in popularity, so take a break from sunbathing and try river rafting or a hike through the jungle.

A city trapped in time, Havana captures the imagination like no other. Faded glamour meets careful colonial-era reconstruction with a backdrop of irresistible colour. Walk El Malecón, the walkway bordering the ocean; visit Old Havana and the Catedral de San Cristóbal; and listen for salsa music, open-air bazaars and parties that last all night.

It’s not just for spring-breakers. Cancun, with its golden beaches and perfect climate, is the premiere coastal destination in Mexico. And while there is certainly a 365-day party available for college students, resorts cater well to families and to those seeking solitude. This Yucatan paradise is also the gateway to the ruins of Tulum and Chichén Itzá.