This Swiss winter wonderland is also a summer playground. Snow-frosted peaks tower above charming towns and villages like Interlaken. Its position, between lakes Thun and Brienz, makes it a perfect base for cable-car rides up Jungfrau, Mönch and Eiger, or for hikes from the traditional village of Grindelwald. Thun offers exciting summer diving and sailing. To the west, the glitzy resort town of Gstaad attracts Europe's wealthy. The Jungfrau Railway boasts Europe's highest station. The region is accessible by bus or car.

Lucerne is an ancient town with strikingly modern sensibilities. One of Europe’s oldest covered bridges serves as its centrepiece, and fresco-adorned historic houses line the streets, but it’s also home to the cutting-edge KKL, a concert hall and art gallery. Take the cableways up the Pilatus, Stanserhorn or Rigi mountains for breathtaking views, or see Lake Lucerne on a steamship cruise.

When most people think of Zermatt, they think of one thing: The Matterhorn. This ultimate Swiss icon looms over Zermatt, first drawing visitors here in the 1860s. The village of Zermatt itself is lovely and car-free, with old-fashioned brown chalets and winding alleys. (Don’t worry, you don’t have to walk everywhere—there are electric vehicles and horse-drawn cabs.) Skiing in the region often lasts through early summer, but when the weather’s warmer, it’s a great time to hike.

This Italian-speaking region in Southern Switzerland is on the border with Italy. Bellinzona is the capital, and Lugano is the most important city in the canton, known for its beautiful waterfront, steep hillsides and gorgeous lake views. Castelgrande is a lovely medieval castle overlooking the city that has recently been restored. The Centovalli Railway is a scenic train that operates between Locarno, Switzerland and Domodossola, Italy, traveling through the breathtaking "Hundred Valleys." Lake Como is nearby, the home of People magazine’s “Sexiest Man Alive,” George Clooney.

The largest city in Switzerland is a major contemporary art and shopping destination. Important artworks are displayed in the Kunsthaus and the Rietberg Museum. Those who consider shopping an art can hone their skills along Bahnhofstrasse and Niederdorf. Chagall's stained-glass windows in the Fraumünster amaze. Zurich's 500 clubs and bars, including several in swimming pools, pulse with life till the early hours. This city on Lake Zurich has excellent public transport and a free bike-hire system.

Located in the southwestern part of Switzerland, in its French-speaking part between Lake Geneva and Lake Neuchâtel, the Canton of Vaud is a vacation destination where life is good. Easily accessible thanks to the proximity of Geneva international airport and an exceptionally dense public transport network, the region offers all the necessary infrastructures, from five-star palaces to charming guest rooms. The diversity of its landscapes, from the peaks of the Alps, to the lakeside towns of Lausanne and Montreux, to the wide open spaces of the Jura and the authentic charm of the countryside, concentrates all the facets of Switzerland in one territory. The beautiful towns and villages, such as Lausanne, Montreux, Nyon, Morges and Yverdon-les-Bains, are steeped in centuries of history and rich in captivating culture. This region has influenced and inspired artists over the years, from Lord Byron and Audrey Hepburn to Charlie Chaplin and Freddie Mercury. But the region is best known for its art of living. Local or internationally renowned events, outdoor sports activities, regional know-how, typical and high level gastronomy, excellent wines, living traditions, cultural offer... are all elements that seduce visitors.

Skiiers have flocked to Mont Tremblant since its first chairlift and lodge opened in 1939. Now, though, it's just as popular with snowboarders, who love its 18 acres of ramps, rails and jumps, and its Olympic-caliber superpipe. Don't fret, though, because despite its name, this mountain doesn't actually tremble... unless you've tossed back a few too many in one of the village's bars!

Known for its markets and its striking 19th-century limestone architecture, Kingston is a great base for exploring the Thousand Islands and the St. Lawrence River and its national park. Visit Wolfe Island on the free ferry, or hunt for antiques in nearby villages.

New York’s Finger Lakes region takes its name from 11 freshwater lakes placed like a handprint between Lake Ontario and the Pennsylvania border. Skiing, hiking and biking trails traverse the landscape; visitors can also indulge in various wine, cheese and beer trails. The area offers a culinary bounty, with an emphasis on farm-to-table cuisine. Rich history and culture are found throughout the region, with one attraction more inviting than the next.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

We won't lie: Niagara Falls is uber-touristy. There are wax museums and a Ripley's Believe It or Not Museum, and if it's a fast-food chain, you can probably find it here. But even the most jaded hipster shouldn't pass up a chance to visit this town, because the Falls themselves are spectacular.

Located in the very Northwest corner of Pennsylvania, Erie is the State's only Great Lakes port city. The Lake is the main attraction in Erie, with the sparkling water giving Erie its nickname, "Gem City." The nearby peninsula of Presque Isle State Park provides residents and visitors ample opportunities for outdoor activities such as sailing, swimming, hiking, and biking. The city is also part of the Snowbelt, famous for the winter wonderland created by the lake effect.

If you’re a history buff and a die-hard foodie, Chicago’s your kind of town. Take an architectural-history walking tour, then dine at Alinea (the most celebrated molecular-gastronomy restaurant in the U.S.). And don’t miss the Museum of Science and Industry, the biggest science museum in the Western Hemisphere.