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Nutrients, Volume 16, Issue 13 (July-1 2024) – 199 articles

Cover Story (view full-size image): There is currently no treatment for ASD for providing significant improvement in core symptoms. The aim of this pilot study was to evaluate the efficacy of the biological response modifier Juvenil in modulating the microbiome of children with ASD and, in particular, whether Juvenil is able to alleviate the symptoms of ASD. To confirm Juvenil’s impact on the gut microbiome, stool samples were collected from all children and the microbiome’s composition was analyzed. In total, 20 children with ASD and 12 neurotypical children were included in our study. This pilot study demonstrated that the gut microbiome of ASD children differed significantly from that of healthy controls and was converted by Juvenil supplementation toward a more neurotypical type. In parallel, Juvenil positively modulated children’s autism symptoms. View this paper
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