Nutrients, Volume 13, Issue 2 (February 2021) – 430 articles
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This review provides an overview of the early life factors that affect gut microbiota colonization and maturation, neuronal and immune system development, as well as focusing on the impact of early life nutrition from pre-conception up to 3 years of age. During this formative time, microbes interact with the host to program a variety of systems determining early life development and fine-tunning the balance between health and disease. Early life microbiota is dynamic and highly sensitive to disruptions, some of which have been linked with neurodevelopmental diseases and immune-related pathologies. More research is needed in order to untangle the complex relationship among early life nutrition, intestinal microbes and the brain during critical temporal windows of development. View this paper
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