Manchester United take on Sevilla at Old Trafford in the first leg of the Europa League quarter-final on Thursday night.
United have already defeated Barcelona and Real Betis, who are above Sevilla in the La Liga table, in the Europa League this season and they are heavy favourites to win the competition for the second time since it was rebranded.
Sevilla have struggled this term and they sit in the bottom half of La Liga. They recently sacked Jorge Sampaoli and Jose Luis Mendilibar, who has managed multiple teams in Spain throughout his career, has taken charge.
Regarding the team news, Casemiro is available for selection again and returns to the starting line-up, but Marcus Rashford, who has scored 28 goals this season, sustained an injury against Everton last weekend and is out through injury, just like Luke Shaw.
Shaw was brought off in the first half in the recent win against Brentford and has been sidelined since.
Recap the events from Old Trafford.
Key Events
Sabitzer gives reason to explain draw
Marcel Sabitzer thinks the draw against Sevilla might have been caused by a lack of focus late in the game.
Just like against Everton at the weekend, United were outstanding in the first half of the match and they were good value for their two-goal lead at half-time, with Marcel Sabitzer netting a brace thanks to some brilliantly worked attacks.
Although the lead could have been more at the break, the tempo dropped after the interval and, following multiple questionable substitutions from Erik ten Hag, Sevilla slowly began to grow in belief and confidence.
Ten Hag's bizarre decisions cost United vs Sevilla
A banner was unfurled in the Sevilla end that read 'We've got a dream' and their supporters ignited a flare. Manchester United should have doused the dream.
Instead it is still alive. United scored all four goals only two of them were in their own net. They did their utmost to make a contest of a tie when its competitiveness ought to have ended after 90 minutes in Manchester.
Tyrell Malacia's dithering defending gave Sevilla a lifeline in the 84th minute and a header that ricocheted in off the dumbstruck head of Harry Maguire in the 92nd minute continued Sevilla's hex over United.
United player ratings as Martial and Sabitzer good
David de Gea
Had next to nothing to do against a tepid Sevilla attack but then Sevilla got a goal back denying a third consecutive clean sheet for the United No.1. 6
Aaron Wan-Bissaka
Another positive performance from a right-back who is now edging his duel with Diogo Dalot. Wan-Bissaka continues to thrive in his unlikely alliance with Antony. 7
Raphael Varane
Did next to nothing wrong in his 45 minutes before he came off after going down injured towards the end of the half. 7
FULL-TIME!
United throw away a two-goal advantage - disaster.
Varane and Martinez also sustained injuries.
Martinez injured
Martinez lifted off the pitch with an ankle injury. That really doesn't look good.
United have used all their substitutions and will play with 10 men.
Malacia deflected it
The ball deflected off Malacia but De Gea should have done better.
GOAL! 2-1 SEVILLA!
Oh dear, Sevilla have scored and Ten Hag really won't be happy.
An own-goal from De Gea, who turns it into his own net at the front post.
CHANCE!
A big chance for Malacia, who takes too long on the ball.
He should have scored from there.
Just 10 minutes left
We're heading into the latter part of the game now.
Pellistri coming on
Another change will be made.
Juventus are wining elsewhere.
Sevilla pushing for a goal
United should have killed the tie by now.
That is the only criticism of them again.
This referee is poor
Sabitzer has just been penalised for trying to win a header.
It really wasn't a foul.
Antony has annoyed
Another yellow card for Sevilla - Acuna has not been happy with Antony since that kick.
Naughty from Antony
Antony looks to have kicked out at Acuna.
He's been naughty there.
The changes are made
Eriksen, Weghorst and Elanga ON.
Fernandes, Sancho and Martial OFF.
CHANCE!
Antony hits the bar. Great effort and unfortunate not to score.
Three changes
Looks like Weghorst, Eriksen and Elanga are coming on.
The game did need an injection of energy.
Some fatigue
This is United's 50th game of the campaign, which means they've played more than last season.
The tempo has dropped
United’s intensity has noticeably dropped this half. It would be a bit of a disappointment for Ten Hag if they only win this 2-0 as they were so dominant and creative in most of the first half. Substituting Varane has not helped but Maguire has started his evening confidently.
Just like Everton
United dominated the first half and returned from the break slowly, which is exactly what is happening here. Sancho looks to be struggling with confidence and could do with a goal.
Better from Sevilla
It's been a good start to the second half for Sevilla, although it couldn't have got much worse.
CHANCE!
Antony cuts inside and his effort just curls around the post.
We've seen those hit the net on a few occasions.
Varane comes off
Maguire ON.
Varane OFF.
