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Interhemispheric Integration after Callosotomy: A Meta-Analysis of Poffenberger and Redundant-Target Paradigms
The central role of the corpus callosum in integrating perception and cognition across the cerebral hemispheres makes it highly desirable for...
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Perceptual Functioning
Perceptual disorders are not part of the diagnosis criteria for schizophrenia. Yet, a considerable amount of work has been conducted, especially on...
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Reduced chemodiversity suppresses rhizosphere microbiome functioning in the mono-cropped agroecosystems
BackgroundRhizodeposits regulate rhizosphere interactions, processes, nutrient and energy flow, and plant-microbe communication and thus play a vital...
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Epiphytic common core bacteria in the microbiomes of co-located green (Ulva), brown (Saccharina) and red (Grateloupia, Gelidium) macroalgae
BackgroundMacroalgal epiphytic microbial communities constitute a rich resource for novel enzymes and compounds, but studies so far largely focused...
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Context-specific functions of chromatin remodellers in development and disease
Chromatin remodellers were once thought to be highly redundant and nonspecific in their actions. However, recent human genetic studies demonstrate...
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Genome-wide Cas9-mediated screening of essential non-coding regulatory elements via libraries of paired single-guide RNAs
The functions of non-coding regulatory elements (NCREs), which constitute a major fraction of the human genome, have not been systematically studied....
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Regulatory Potential of Noncoding RNAs Co-Located with Cardiomyopathy Related Genes
AbstractNoncoding RNAs (ncRNAs) play an important regulatory role in the activity of genes essential for the development and functioning of...
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The Cognitive Profile of Atypical Parkinsonism: A Meta-Analysis
Atypical Parkinsonism (AP) syndromes are characterized by a wide spectrum of non-motor symptoms including prominent attentional and executive...
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The Disadvantages of Automation in Clinical Microbiology
The procedures of clinical microbial diagnosis are complicated and expensive, the potential advantages expected from implementation of Total...
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Novel functional insights into the microbiome inhabiting marine plastic debris: critical considerations to counteract the challenges of thin biofilms using multi-omics and comparative metaproteomics
BackgroundMicrobial functioning on marine plastic surfaces has been poorly documented, especially within cold climates where temperature likely...
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Service provision of genetics health care in Portugal
In recent decades, genetics has undergone important technological advances. The rapid shift to genomics has made a strong impact on health systems...
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Clinical and Molecular Delineation of Cutis Laxa Syndromes: Paradigms for Elastic Fiber Homeostasis
Cutis laxa (CL) syndromes are a large and heterogeneous group of rare connective tissue disorders that share loose redundant skin as a...
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The Factor Structure of Cognitive Functioning in Cognitively Healthy Participants: a Meta-Analysis and Meta-Analysis of Individual Participant Data
Many neuropsychologists are of the opinion that the multitude of cognitive tests may be grouped into a much smaller number of cognitive domains....
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Deep phenotypic analysis of psychiatric features in genetically defined cohorts: application to XYY syndrome
BackgroundRecurrent gene dosage disorders impart substantial risk for psychopathology. Yet, understanding that risk is hampered by complex...
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Interactions between rootstocks and compost influence the active rhizosphere bacterial communities in citrus
BackgroundWhile the rootstock genotype (belowground part of a plant) can impact rhizosphere microbial communities, few studies have examined the...
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Functional implications of paralog genes in polyglutamine spinocerebellar ataxias
Polyglutamine (polyQ) spinocerebellar ataxias (SCAs) comprise a group of autosomal dominant neurodegenerative disorders caused by (CAG/CAA) n ...
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Peroxiredoxins in erythrocytes: far beyond the antioxidant role
The red blood cells (RBCs) are essential to transport oxygen (O 2 ) and nutrients throughout the human body. Changes in the structure or functioning of...
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Shortening the Frommelt Attitude Toward the Care Of the Dying Scale (FATCOD-B): a Brief 9-Item Version for Medical Education and Practice
End-of-life care training has gaps in helping students to develop attitudes toward caring for the dying. Valid and reliable assessment tools are...
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Stable functional structure despite high taxonomic variability across fungal communities in soils of old-growth montane forests
BackgroundMajor advances over the past decade in molecular ecology are providing access to soil fungal diversity in forest ecosystems worldwide, but...
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An evolutionary account of impairment of self in cognitive disorders
Recent research has proposed that certain aspects of psychosis, as experienced in, e.g., schizophrenia (SCZ), but also aspects of other cognitive...
