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Molecular Biology and Neurobiology of Choline Acetyltransferase
In the 45 years since the first description of choline acetyltransferase (ChAT; EC 2.3.1.6.), significant progress has been made in characterizing... -
Molecular biology and neurobiology of choline acetyltransferase
In the 45 years since the first description of choline acetyltransferase (ChAT;EC 2.3.1.6.), significant progress has been made in characterizing the...
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Introduction
Viruses have played a pivotal role in the dramatic elucidation of life’s chemical foundation during the past three decades. Their borderline position... -
Transmission Studies of Psychiatric and Neurological Disease
The attempt to transmit disease to animals is one approach to a viral etiology of human disease. This strategy has been crucial for understanding... -
Physical-Chemical Properties
Essential to understanding how viroids function is the determination of their nucleotide sequences. Within each viroid sequence is all the... -
Aging-Related Pathology in Human Neuroblastoma and Teratocarcinoma Cell Lines
Humans and other primates take decades to age and even the 2–3 years required in a short-lived mammal like the mouse or rat is an impractically long... -
Strategy of Replication of the Viral Genome
Unlike higher organisms, viruses utilize a wide range of strategies in the replication of their genome. This is clearly a consequence of their need... -
Alzheimer’s disease
Alzheimer’s disease can be considered a late-onset system degeneration, characteristically involving certain populations of cholinergic neurons but...