Companies that mitigate climate change reduce their cost of capital
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Updates every hour. Last Updated: 14-Jun-2024 12:09 ET (14-Jun-2024 16:09 GMT/UTC)
- Using nanoruler technology, the optimal size more likely to accumulate in brain tumors was studied.
- The size effect of nanomedicine on passive GBM targeting with size-tunable poly(ethylene glycol)-grafted copolymers (gPEGs) as polymeric nanorulers was explored.
- It was demonstrated that the threshold for brain tumor tissue permeability was in the range of 10 to 30nm.
- By adjusting the size of the gPEGs to 10 nm, an unprecedentedly high brain tumor accumulation was obtained (19 times higher than that in the normal brain region and 4.2 times higher than that of 30 nm of gPEGs).
- The size-optimized gPEGs can be loaded with contrast agents or anti-cancer drugs to enable more effective cancer diagnostics or treatments.
Cervical cancer is the fourth most common cancer in women. The current cancer screening methods are mostly invasive and some of them involve detection of human papillomavirus (HPV) DNA. However, recent advances in the field suggest detection of HPV16 E7 oncoproteins as a more clinically relevant method for screening cervical cancer. Now, researchers have developed a noninvasive alternative method to detect HPV oncoproteins in urine samples that could revolutionize cervical cancer screening.
Researchers have created tiny, vehiclelike structures which can be maneuvered by microscopic algae. The algae are caught in baskets attached to the micromachines, which have been carefully designed to allow them enough room to continue swimming. Two types of vehicles were created: the “rotator,” which spins like a wheel, and the “scooter,” which was intended to move in a forward direction but in tests moved more surprisingly. The team is planning to try different and more complex designs for their next vehicles. In the future, these mini algae teams could be applied to assist with micro-level environmental engineering and research.
Immobilizing small synthetic molecules inside protein crystals proves to be a promising avenue for studying intermediate compounds formed during chemical reactions, report scientists from Tokyo Tech. By integrating this method with time-resolved serial femtosecond crystallography, they successfully visualized reaction dynamics and rapid structural changes occurring within reaction centers immobilized inside protein crystals. This innovative strategy holds significant potential for the intelligent design of drugs, catalysts, and functional materials.
Genotyping techniques can be used to select fruit trees with desired traits at the seedling stage, increasing the efficiency of fruit tree breeding. However, so far, there are multiple different genotyping systems, each generating distinct datasets. In a recent study, Japanese scientists revealed that integrating genomic data obtained with different genotyping systems can effectively combine with historical data, leveraging the accuracy of genomic predictions.
While, in theory, precipitation impacts the Earth’s radiation budget, the radiative effects of precipitation (REP) are poorly understood and excluded from most climate models. Hence, a new study examined the role of REP in the global and regional energy budgets and hydrological cycles, finding that REP significantly contributes to temperature and precipitation variations at different geographical scales, especially in the Arctic warming. This highlights the relevance of including REP in climate modeling for improved accuracy.
A group from Nagoya University in Japan has discovered how mosquitoes identify their own species by listening for the frequency of their wingbeats, which they use to avoid wasted mating efforts. The group hopes to use the research to develop tools to control the reproduction of specific mosquito species using artificial flight sounds.