Is there any possible way Las Vegas could not be on our "best nightlife" list? The only way we could possibly omit it is on a technicality—since you can do pretty much anything 24/7 in Vegas, it might be wrong to call it "nightlife."

Known for the stunning backdrop afforded by the towering Wasatch Mountains – and the endless opportunities for outdoor recreation they provide – Salt Lake offers visitors a uniquely vibrant and dynamic urban experience. As one of North America’s most accessible destinations, Utah’s capital city offers year-round excitement and activities for the entire family, alongside a contemporary edginess and vitality that’s helped the “new” Salt Lake become a renowned culinary destination.

Flanked by lakes, mountains and intriguing rock formations, Grand Junction offers a different side of Colorado. Mild weather year-round creates an agricultural oasis for 22 different wineries. Mountain bike along winding desert trails, wine and dine next to majestic rivers, and peruse a variety of shops, galleries and boutiques. For breathtaking natural beauty, don’t miss Grand Mesa National Forest and Colorado National Monument’s 23-mile stretch of scenic overlooks.

Moab attracts all types of outdoor adventurers. Mountain biking is huge here—experts claim it has some of the best trails in the world—as are rock-climbing and hiking. And the setting, with its gorgeous red rocks, can't be beat.

Once a frontier mining town, Durango draws thousands of tourists year-round for the myriad outdoor recreational activities and scenic beauty. Mountain bikers, rafters, kayakers, horseback riders, rock climbers, hikers, campers, hunters and fishermen are drawn to the two-million acre San Juan National Forest and to the San Juan mountains, the largest range in the Rockies. But the city's biggest tourist draw is a nine-hour historic train ride in a vintage steam locomotive. The Durango and Silverton Narrow Gauge Railroad, which hauled precious metals in the 1880s, now takes tourists for a 47-mile, open-air journey through mountains and forests and past abandoned mines to historic Silverton and back. Children and train buffs will relish the chance to climb into a locomotive and pore over railroad memorabilia at the railroad's museum. Skiers flock to the Durango Mountain Resort in winter, which also offers hiking, fishing, rafting and horseback riding in warmer months. Slow down your pace with a stroll past splendidly restored Victorian buildings in historic Downtown Durango and wind up a very active weekend in a local brewpub or saloon.

It may be difficult to believe that a mere half century ago, the land beneath Page, Arizona and Lake Powell was a vast and bleak desert landscape. Carved out of the rocky terrain, Page sits atop Manson Mesa and overlooks the 186-mile long lake, the dramatic Glen Canyon Dam and the surrounding canyons, arches and historical Native ruins. A mild climate year-round makes Page the perfect central hub for visiting the Grand Circle sites, as well as the neighboring Navajo Nation, home to Window Rock.

We've heard Toronto described as "New York City run by the Swiss," and it's true—you can find world-class theatre, shopping and restaurants here, but the sidewalks are clean and the people are friendly. The best place to start is literally at the top—the CN Tower, the tallest freestanding structure in the Western Hemisphere.

A cosmopolitan city known as the "cultural cradle of Canada," Winnipeg is family friendly with plenty of charm. It boasts a dazzling arts, theatre and indie music scene, as well as lip-smacking dining options to tantalize every taste bud. Experience nine acres of shopping and interactive fun at the Forks Market or explore Winnipeg’s diverse neighborhoods like the historic French Quarter and Exchange District or the boho chic Osborne Village.

We won't lie: Niagara Falls is uber-touristy. There are wax museums and a Ripley's Believe It or Not Museum, and if it's a fast-food chain, you can probably find it here. But even the most jaded hipster shouldn't pass up a chance to visit this town, because the Falls themselves are spectacular.

Montreal, c’est si bon! This French-speaking city is considered the cultural capital of Canada, and is a cosmopolitan celebration of Québécois style. A horse-drawn carriage ride around the cobblestone streets and grand buildings of Vieux-Montréal will give you a taste of European flavour. The Basilique Notre-Dame is a confection of stained glass, and the Plateau Mont-Royal district will delight you with its quaint boutiques and cafés. Dig in to a massive plate of poutine to fuel up for a tour of the epic Olympic Park.

Ottawa is a compact, clean, cleverly planned centre of culture and politics. And it's an ideal choice for a weekend getaway. Start downtown at the architecturally stunning National Gallery of Canada, and don't miss the Canadian Nature Museum and the National Aviation Museum. Rideau Canal offers boating in the summer and ice-skating in the winter. Gatineau Park attracts cyclists and walkers, while Byward Market blends old and new Ottawa.

Whistler, British Columbia, is a short trip from Vancouver by road or air. The stunning landscape, pedestrian-only Village and genuine, down-to-earth mountain culture make Whistler an unforgettable year-round destination. Winters provide reliable snow for skiing, snowboarding and Nordic sports while golf, mountain biking and hiking fill the warmer months. Festivals, spas, restaurants and bars combine with endless outdoor activities to make Whistler the ultimate place to escape and unwind.

What happens when a "gassy" Englishman rows into town feeling thirsty? A pub is born. And from that a city—in this case Vancouver. Though the pubs are plentiful, food and drink aren’t the only things to take in during your trip. In its 150 years, Vancouver has grown into a cosmopolitan city nestled in the great outdoors. Enjoy the snow-capped mountains, waterfront forests, cityside beaches, Olympic history and the world’s highest suspension bridge. Hipsters welcome. (Don’t worry, they don’t bite.)