Research
Learn about published research as well as leading-edge basic and translational research initiatives from St. Jude laboratories.
Distinct molecular profiles lead to a better understanding of acute leukemia
Distinct molecular profiles in acute myeloid leukemia (AML) and T-cell acute lymphoblastic leukemia/lymphoma (T-ALL/LLy) with PICALM::MLLT10 (PM) fusions shed light on potential targeted therapies for improved outcomes.
A glimpse beyond life and death: Exploring the biology of the MICOS complex
See how new model offers glimpse into vital mitochondrial complex
Influenza virus provides first evidence of bats’ potential as an intermediate host
Explore research showing bats may be an intermediate influenza host.
Blazing a TRAIL in acute myeloid leukemia treatment
See how studies into AML drug reveals new potential target
Study reveals the neurochemical gatekeeper to learning and the key to unlocking it
St. Jude research uncovers neural secrets behind our capacity to learn
Drug which blocks stress granule formation offers insight into biomolecular condensates
See how G3BP inhibitors represent turning point in RNP granule research
Following the breadcrumbs: Gain-of-function mutation leads researchers to new therapeutic target for pediatric AML
Explore the mechanistic insights behind novel pediatric AML therapeutic target
Exploring the interplay between vaccines and immune system development in infants
Explore new research delving into pediatric immune responses to vaccination
CRISPR kickstarts combination drug discovery for neuroblastoma
A CRISPR screen reveals a potential combination therapy for relapsed neuroblastoma.
Finding the big-TIME players holding back CAR T–cell therapy for high-grade gliomas
Explore how tumor-associated macrophages shape CAR T-cell therapy efficacy in high-grade gliomas.