![Molecular structure model](https://cdn.statically.io/img/www.port.ac.uk/sites/default/files/styles/hero_mobile/public/media/images/webimage-3D51A87D-FB8C-4B9E-96A1728264231E82.jpg?h=a9c43f9b&itok=YqqlO2KP)
Sidebar navigation
![Molecular structure model](https://cdn.statically.io/img/www.port.ac.uk/sites/default/files/styles/hero_mobile/public/media/images/webimage-3D51A87D-FB8C-4B9E-96A1728264231E82.jpg?h=a9c43f9b&itok=YqqlO2KP)
Using computation to explore the natural world
Location: King Henry Building
Our Sequencing and Bioinformatics laboratory is the hub for working with a variety of DNA and RNA sequencing tools, as well as high-throughput nanopore sequencers.
Through hands-on experiments, you'll see how DNA and RNA pass through tiny pores and are then decoded into their constituent parts by machine learning algorithms.
The facility includes a wide range of computational tools to analyse nanopore sequencing data and other next-generation sequencing platforms. Additionally, we maintain pipelines for sequencing applications such as whole (meta) genome assemblies, RNA sequences, targeted sequences, and amplicon sequences.
Our lab collaborates on a wide range of research projects, especially those that use Illumina and Oxford Nanopore Technologies (ONT) for high-throughput sequencing, and has recently served as a virus sequencing site for the COVID-19 Genomics UK (COG-UK) Consortium. We also host a range of research projects within the Centre for Enzyme Innovation (CEI), exploring the genomes of naturally occurring microorganisms to identifying enzymes with potential industrial applications.
Equipment and amenities
- MinION nanopore sequencer (Oxford Nanopore Technologies)
- GridION nanopore sequencer (Oxford Nanopore Technologies)
- P2Solo PromethION nanopore sequencer (Oxford Nanopore Technologies)
- VolTrax automatic sample preparation (Oxford Nanopore Technologies)
- Qubit 4 fluorometer (Invitrogen)
- DS-11 Spectrophotomer (Denovix)
- 4150 TapeStation (Agilent)
- Bioinformatics High Performance Computing (HPC) cluster, which includes:
- Four 24-CPU compute nodes with 768 GB RAM
- Two 24-CPU compute nodes with 384GB RAM
- One GPU compute node with two V100 Tesla GPUs and 1,024 GB RAM
- One head node with 48 CPUs and 384 GB RAM
- One PB of redundant data storage connected via a 10GbE Network
Contact us
If you're interested in our sequencing and bioinformatics facilities – please email seqandbio@port.ac.uk or call +44 (0) 23 9284 2043.
Related facilities
Biophysical laboratories
Use professional-standard equipment to explore how the structures and functions of molecules change under different conditions.
![Female student on computer in biology lab](https://cdn.statically.io/img/www.port.ac.uk/sites/default/files/styles/card_mobile/public/media/images/webimage-7B8509D0-F900-4F30-857BF87E7258EC1F.jpg?itok=uqnoT1Hr)
Institute of Life Sciences and Healthcare
We're exploring disciplinary boundaries to discover, understand and develop knowledge for the benefit of the environment and humankind.
![Close up of a gloved hand and some petri dishes](https://cdn.statically.io/img/www.port.ac.uk/sites/default/files/styles/card_mobile/public/media/images/webimage-DE3987EB-2ED9-45EB-97AA4F97D6FA8381.jpg?itok=ErmLYg-O)
Centre for Enzyme Innovation
At the Centre for Enzyme Innovation, we are working to solve one of the most pressing environmental issues facing our planet.
![Plastics bottles - Centre for Enzyme Innovation](https://cdn.statically.io/img/www.port.ac.uk/sites/default/files/styles/card_mobile/public/media/images/CEI-plastic-bottles-600x600.jpg?h=795c9d5c&itok=45sCMviV)
Related courses
Where to find us
Sequencing and Bioinformatics Group laboratory
King Henry Building
King Henry I Street
Portsmouth
PO1 2DY