![Shaded cut watermelon on top of other watermelons](https://cdn.statically.io/img/media.springernature.com/w735h400/nature-cms/uploads/cms/pages/5337/top_item_image/06_NSMB-Hero-JUN24-a5efdc41f0bd178d06289fe6a5779229.jpg)
A proteomics atlas of citrullination
Here, Rebak et al. utilise proteomics to establish an atlas of protein citrullination, and implicate citrullinated sites as potentially clinically relevant. Citrulline was discovered in watermelons.
Here, Rebak et al. utilise proteomics to establish an atlas of protein citrullination, and implicate citrullinated sites as potentially clinically relevant. Citrulline was discovered in watermelons.
Overexpression of the RNA methyltransferase METTL6 leads to increased proliferation and promotes cancer. Our cryo-electron microscopy (cryo-EM) and biochemical analyses reveal that METTL6 requires seryl-tRNA synthetase as a cofactor to efficiently generate 3-methyl-cytosine in serine tRNAs.