Reports, Volume 7, Issue 2 (June 2024) – 28 articles
Cover Story (view full-size image):
This study estimated the prevalence of drug interactions with chloroquine (CQ) or hydroxychloroquine (HCQ) in COVID-19 inpatients during the pandemic waves and their association with hospitalization-related outcomes. In a sample of 487 patients with a mean age of 77.1 years (47.8% females), hospitalized for COVID-19 from March to December 2020, and treated with CQ or HCQ, we found that 255 (52.4%) had one drug interaction with CQ or HCQ, and 114 (23.4%) had ≥2 interactions. The most frequent drugs interacting with CQ or HCQ were lopinavir/ritonavir, azithromycin, tocilizumab, levofloxacin, clarithromycin, amlodipine, and trazodone. The presence of drug–drug interactions did not seem to impact the hospitalization duration and outcomes. View this paper
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