Update in The Fight Against Dengue and Zika As reported by Catherine Offord in Science, a team led by Gong Cheng (gong cheng) of Tsinghua University has discovered a bacterium in mosquito guts that could add to our approaches against Dengue and Zika viruses. The bacterium, named Rosenbergiella_YN46, was found to significantly reduce the viral load in mosquitoes by secreting an enzyme that acidifies the gut. That acidification seems to disrupt the viral proteins necessary for infection. Globally, Dengue affects 400 million people a year, and vaccine availability remains a challenge, with groups like Takeda and the Instituto Butantan working hard at developing new solutions. These findings are early and many questions including scalability remain to be explored yet the potential implications are exciting: - Could this bacterium's natural occurrence explain low dengue incidence in certain areas? - Might it work synergistically with other microbial controls like Wolbachia? - Could plants harboring Rosenbergiella_YN46 be used for natural mosquito population control? All these questions are sure to trigger more innovation in this space! #Dengue #Zika #MosquitoControl #Innovation #PublicHealth References: https://lnkd.in/esnbyFC7 https://lnkd.in/ejSTG3PG Illustration EMxMJ
Eric Merle’s Post
More Relevant Posts
-
🌎 Tomorrow is World Dengue Day! Dengue is caused by the dengue virus (DENV), which is transmitted by mosquitoes. Currently, there is no specific treatment. The severity of complications is increasing which, together with frequent epidemics and pandemics, places a significant burden on healthcare systems. Factors such as urbanization, water scarcity and environmental change make dengue a disease of the future. This year, Peru and Rio de Janeiro declared a public health emergency, due to the rising numbers of dengue infections. 🇵🇪 🇧🇷 In collaboration with a major pharmaceutical company, we have successfully identified predictive protein biomarkers for dengue deterioration, bringing early intervention and cost-effective treatment of this increasingly deadly disease one step closer. 🔬 Learn about the impact of dengue on global health and how predictive biomarkers for dengue deterioration could impact global healthcare in our article ‘Biomarker Discovery for Predicting Dengue Deterioration: A Breakthrough Study’. 📖 Please feel free to contact us if you have any questions about our research or are looking for opportunities to collaborate. Follow us and stay tuned for more news on precision medicine and proteomics! ✨ #denguefever #globalhealthcare #medicalresearch #biomarker
To view or add a comment, sign in
-
-
The largest study of its kind on the use of #Wolbachia (wMel strain) to prevent the transmission of #dengue virus has been completed, and the results are promising. Following a large-scale multi-year release of wMel-carrying #Aedesaegypti #mosquitoes, scientists in #Colombia recorded significant reductions in dengue case incidence. The methods and results of this groundbreaking study are published in PLOS Neglected Tropical Diseases. Aedes aegypti mosquitoes are responsible for most dengue transmission in urban areas. Early laboratory research studies have shown that these mosquitoes cannot transmit the virus when infected with Wolbachia. To test these results in the field, two parallel studies were designed and implemented in the Colombian cities of Bello, Medellin, and Itagui. Mosquitoes infected with wMel were released regularly between October 2016 and April 2022, and the incidence of dengue virus was closely monitored both in the clinical setting and in the field. Reductions of 95% and 97% in dengue clinical cases were observed. These results are consistent with those of similar studies, showing that nature can harbor unexpected allies in the global fight against this #neglectedtropicaldisease. #globalhealth https://ow.ly/inBW50QzK32
To view or add a comment, sign in
-
-
On #WorldMosquitoDay, let's shed light on a pressing issue. Mosquitoes, vectors for diseases like Dengue, Zika, and West Nile Virus, impact over half the global population. As insecticides are vital in controlling mosquito-borne diseases, understanding their resistance mechanisms becomes even more crucial. Causaly's latest insights delve into the genetic mutations and resistance mechanisms in mosquitoes, emphasizing the need for innovative control strategies. Read the full blog here: https://hubs.la/Q01_tQtv0 #mosquitoes #insecticideresistance
To view or add a comment, sign in
-
On #WorldMosquitoDay, let's shed light on a pressing issue. Mosquitoes, vectors for diseases like Dengue, Zika, and West Nile Virus, impact over half the global population. As insecticides are vital in controlling mosquito-borne diseases, understanding their resistance mechanisms becomes even more crucial. Causaly's latest insights delve into the genetic mutations and resistance mechanisms in mosquitoes, emphasizing the need for innovative control strategies. Read the full blog here: https://hubs.la/Q01_tQtv0 #mosquitoes #insecticideresistance
Understanding Insecticide Resistance in Mosquitoes
causaly.com
To view or add a comment, sign in
-
The #Chikungunya virus is expanding globally and infecting more people during epidemics, aided mainly by transmission cycles in urban environments. Luckily, the race is on to design the first clinical treatment for Chikungunya. Treatments using antibodies, nanoantibodies, interferons, and antiviral agents are at various stages of development. Furthermore, prophylactic treatments that prevent viral replication are under evaluation as a measure for containing epidemics. Since Aedes mosquitoes are known to drive Chikungunya transmission, researchers are also exploring innovative strategies to reduce their viral load. Compounds such as #Atovaquone have already demonstrated antiviral effects in mosquitoes through brief exposure, which may help reduce their ability to transmit Chikungunya. For the most recent advancements in research on Chikungunya treatment, read articles from Antiviral Research: http://spkl.io/604142c75
To view or add a comment, sign in
-
-
📅 It’s #WorldNTDDay! Neglected Tropical Diseases (NTDs) include several parasitic viral, bacterial, fungal and non-communicable diseases that cause substantial illness for more than one billion people globally. 🦟 Dengue and chikungunya are among the most important diseases caused by arboviruses worldwide, especially in tropical and subtropical regions. These are transmitted to humans by day-biting Aedes aegypti and Aedes albopictus mosquitoes. bioMérieux Immunoassays offer directed against diseases improve access to medically important automated serological assays to optimize patient management. ⤵️
Discover VIDAS® ARBOVIRUSES PANEL
share.biomerieux.com
To view or add a comment, sign in
-
📅 It’s #WorldNTDDay! Neglected Tropical Diseases (NTDs) include several parasitic viral, bacterial, fungal and non-communicable diseases that cause substantial illness for more than one billion people globally. 🦟 Dengue and chikungunya are among the most important diseases caused by arboviruses worldwide, especially in tropical and subtropical regions. These are transmitted to humans by day-biting Aedes aegypti and Aedes albopictus mosquitoes. bioMérieux Immunoassays offer directed against diseases improve access to medically important automated serological assays to optimize patient management. ⤵️
Discover VIDAS® ARBOVIRUSES PANEL
share.biomerieux.com
To view or add a comment, sign in
-
Marketing Manager Africa | Molecular Biology | BIOFIRE Syndromic Testing | Medical Biotechnologist | IVD | Life Sciences | Pharma | Healthcare
📅 It’s #WorldNTDDay! Neglected Tropical Diseases (NTDs) include several parasitic viral, bacterial, fungal and non-communicable diseases that cause substantial illness for more than one billion people globally. 🦟 Dengue and chikungunya are among the most important diseases caused by arboviruses worldwide, especially in tropical and subtropical regions. These are transmitted to humans by day-biting Aedes aegypti and Aedes albopictus mosquitoes. bioMérieux Immunoassays offer directed against diseases improve access to medically important automated serological assays to optimize patient management. ⤵️ #WeArebioMérieux #WorldNTDDay
Discover VIDAS® ARBOVIRUSES PANEL
share.biomerieux.com
To view or add a comment, sign in
-
Inside Sales Specialist | Analista Comercial | Vendas | Pós Vendas | Atendimento ao cliente | Analista de Atendimento
📅 It’s #WorldNTDDay! Neglected Tropical Diseases (NTDs) include several parasitic viral, bacterial, fungal and non-communicable diseases that cause substantial illness for more than one billion people globally. 🦟 Dengue and chikungunya are among the most important diseases caused by arboviruses worldwide, especially in tropical and subtropical regions. These are transmitted to humans by day-biting Aedes aegypti and Aedes albopictus mosquitoes. bioMérieux Immunoassays offer directed against diseases improve access to medically important automated serological assays to optimize patient management. ⤵️
Discover VIDAS® ARBOVIRUSES PANEL
share.biomerieux.com
To view or add a comment, sign in
-
Mosquito 🦟 borne diseases are on the move! Join BlueDot … Climate change and human activity are enabling the spread of mosquito-borne diseases, like dengue fever, to new places. 🦟🌎🦟🌎🦟🌎🦟🌎🦟 #malaria #dengue #denguefever #chikungunya #infectiousdiseases #infectiousdisease
Join us for a ground-breaking webinar where we delve deep into the dynamic landscape of mosquito-borne diseases – specifically malaria, dengue, and chikungunya — and explore the latest trends and impacts on a global scale. Featuring our expert panelists Mariana Torres, MD, Surveillance Manager, Hernán Acosta, MD, Medical Science Liaison, and Nicole N., MSc, Infectious Disease Surveillance Analyst, and hosted by Jannine Krish, MBA, VP of Marketing, during this session we will: 👉 Profile real-life examples of abnormal activity, showcasing how early warning systems can identify high-risk areas and unusual activity 👉 Explore medium and long-term outlooks using our Vector Suitability Score (VSS) model 👉 Examine obstacles when facing unusual activity 👉 Understand the role of AI in gaining real-time awareness and foresight identifying populations with vulnerabilities Gain insights and have your questions answered during our live Q&A! Can’t make it? Register to receive the recording afterward. Register here ---> https://lnkd.in/egsX_qPD #malaria #chikungunya #AI #dengue
To view or add a comment, sign in
-
CEO | A Healthier Democracy | Physician
3moThis update on the fight against Dengue and Zika is fascinating! Eric Merle 👏🏽 The discovery of the bacterium Rosenbergiella_YN46 and its potential to reduce viral load in mosquitoes is a significant step forward in mosquito control efforts. 🙌🏽