EntityRisk’s Post

Health Economics needs to factor in the preventative value of treatments in order for the ongoing drug pricing negotiations to serve society best in the longer term, our Co-Founder and Scientific Advisor Dana P Goldman told a panel event hosted by The Hill.    “The way to save money in healthcare is to keep people out of the hospital,” Dana said. “That's what drugs do when they work best. They keep people out of the hospital. And we are negotiating those prices at the same time we are not solving these preventive healthcare issues that will drive disparities and costs.” For a good example of this dynamic, check out Dana’s blog about Medicare coverage of new obesity treatments: https://lnkd.in/gCTbB2aZ #HEOR #Innovation #DrugPricing #BioPharma #HealthEconomics 

A nice summary from Jason Shafrin on the increasingly persuasive case for lower discount rates in HTA.

 Patrick N. of Affinity Asset Advisors was asked if the end of 2023 were allegedly the best months in biotech history.  “It was a painful preceding few years,” he said. “It feels like the time is probably around now when we start to see people becoming more interested in the sector again. It’s exciting as a biotech investor. Obviously, these companies are going to help people down the road, and they need to be able to raise money to do that, and hopefully with a better market environment that can happen.” Key to long-term success is the ability to accurately model uncertainty. This is why we created our advanced digital PROVEN ™ platform. Check out the full interview with Nosker (part of the SF Healthcare Week conference) here: https://lnkd.in/g8ad4zNV  #HEOR #Innovation #BioPharma #HealthEconomics 

The connection between music and medicine goes back millennia—at least to the Greeks who used musical instruments to try to heal patients. Recently, musician and life sciences investor D.A. Wallach opened up to Endpoints News about his own experience in both worlds. “I think there is sometimes a similarity in the personality type of musicians and scientists,” Wallach said. “It is not a perfect overlap, but there’s a combination of detail-orientation and free-spiritedness that I sometimes recognize in folks who thrive in these worlds. One needs to have an impulse to explore in open-ended spaces and to combine ideas in novel ways in order to generate new materials, and then discipline and obsessiveness are required to take you from there to something tangible.” This interview resonates with our vision in more than one way. Health economics is as much a science as an art, and fine-tuning the right methodology to give a tangible expression to the intangible requires those same qualities and skills. Beyond that, we created our cutting-edge PROVEN ™ platform to help scientists and investors understand better the uncertainty associated with business planning in the life sciences—and in this way to more efficiently enable the kind of innovation Wallach is passionate about.  Read the full interview here: https://lnkd.in/gAnNXQHi #HEOR #Innovation #BioPharma #HealthEconomics 

The impact of the Inflation Reduction Act and the unprecedented drug price negotiations in the US on biotech investing was a major topic at the Financial Times US Pharma and Biotech Summit 2024 in New York. Darius Lakdawalla was joined by Johanna (Rodriguez) Grossman, PhD at NYSE, Harmeet Dhillon at GSK, Amit Sinha at Goldman Sachs on the panel, Soft Landing, Hard Problems. Oliver Barnes, US pharma and biotech correspondent for the Financial Times moderated. The stakes involved in getting launch prices right have never been higher, Darius shared. In the future, it will be harder to compensate for low initial prices with annual price hikes while setting the launch prices too high can result in access limitations. Despite that there are multiple strategies to sustain medical innovation through current market volatility. Darius pointed to dynamic pricing models and better recognizing the social value of innovation in healthcare economic models. These all hinge on modeling uncertainty accurately. The recently released PROVEN platform is the engine Darius and his team are using to accelerate analysis on this, test current thinking and refine our understanding of how pricing works and how to plan for a changing environment. The full video from the summit can be purchased from the event organizers here: https://lnkd.in/ebXx2jk #HEOR #Innovation #DrugPricing #BioPharma #HealthEconomics

When the year started biotech investors had a smaller appetite for risk compared to previous years. Startups have needed to show a good business plan in addition to sound science to get funded. These were key takeaways from this year’s BIO CEO & Investor Conference that took place in New York on February 26. How is that playing out now in May? “There’s the science, and I love the science, but I have been forced to think about the business a lot more over the last two years,” Ellen Hukkelhoven, Head of Biotechnology Investments at Perceptive Advisors, told the conference. “The drug needs to work, it needs to get approved—which is a separate question—and then it needs to sell. Even in preclinical companies, we are thinking about all three of those stages when we invest.” While startups have come up with various strategies to stand out to investors, including offering a preview of their data to their top targets, nothing beats solid economic analysis. This is why we created our advanced PROVEN ™ platform — to help both investors and biotech innovators model uncertainty and predict the value of novel therapies with unprecedented flexibility and precision. #HEOR #DrugPricing #BioPharma #Innovation Link: https://lnkd.in/gW4YUd33

Following ISPOR 2024, we're re-listening to Bioverge Ventures’ founder Neil Littman sharing VC insights into healthcare and the life sciences on Dr. Chris Stout’s Living a Life in Full podcast. “What was once deemed to be science fiction is now increasingly becoming science fact,” he said. “I firmly believe the next great revolution will be in the tools to re-architect our biology, our brains, our chemistry and ourselves. We are already seeing this play out in real time.” A key step along the way is to democratize access for a wider circle of investors to promising biotech deals, and to identify early on those startups which have the potential to contribute the most to patient needs. In order to select the latter, meticulous research and due diligence are paramount. "If I am intellectually honest, I have no idea a priori which one of our portfolio companies is going to have a billion-dollar outcome, but I need to have a relentless focus on the process to ensure we are investing in the right types of companies to give ourselves that statistical probability of success,” Littman added. We created our AI-powered PROVEN platform to help innovators as well as investors model uncertainty with unprecedented accuracy and flexibility and to gauge the value of any potential future treatment. To learn more about our innovative methodology, do not hesitate to reach out. Check out the full podcast here for more insights, including tips how to best manage the potentially complex relationship between VC investors and biotech founders, and a valuable perspective into how an investor’s well-curated network can contribute in diverse ways to the success of an early stage company: https://lnkd.in/dMPF7TSm  #HEOR #DrugPricing #BioPharma #Innovation 

ISPOR 2024 wraps up today! It has been an informative and compelling gathering. Thank you everyone we had an opportunity to meet and reconnect with. If you haven’t caught up with Manish Singh and our team yet, there’s still time - you can find us at booth #318. Again, make sure to ask for details on the new PROVEN platform. #HEOR #ISPOR #DrugPricing #BioPharma #ISPOR24

Are you catching today’s 1:45pm session at ISPOR - “I Have a Better QALY Than You: How to Make Sense of Alternatives to the QALY for Research and Policymaking"? Tell us how you think the debate went, we want to hear your thoughts. #HEOR #ISPOR #DrugPricing #BioPharma #ISPOR24