“There’s a lot to say about how great Lia is, but I’ll try to touch on a few items. Lia embodies what it means to be a leader, innovator and to be someone who empowers others to achieve their dreams. She’s a person of many merits - a founder, innovator, mentor, leader and most of all an awesome person!! There’s very few people that you meet that truly care about other people’s successes, she’s one of them! Over my time at the University of Tennessee, she has been one of the most instrumental people in my success! I’m excited to cheer on as Lia takes on many successes, and will vouch for Lia any day. I’m honored to call Lia a mentor and friend.”
About
Inventor of…
Activity
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Happy Holiday Weekend. Meet “Ricky Ducky”… A gift from my incredible OR team at Orthopedic Associates Surgery Center . #Arthroscopy can be messy…
Happy Holiday Weekend. Meet “Ricky Ducky”… A gift from my incredible OR team at Orthopedic Associates Surgery Center . #Arthroscopy can be messy…
Liked by Lia Winter
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At The De Angelis Group we focus on hiring executive levels such as board of directors, VPs and CXO. Some of our sector specialties are Spine…
At The De Angelis Group we focus on hiring executive levels such as board of directors, VPs and CXO. Some of our sector specialties are Spine…
Liked by Lia Winter
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Our friends at Winter Innovations have developed an incredible solution for more efficient and secure graft stitching: Easy Whip. Check it out at…
Our friends at Winter Innovations have developed an incredible solution for more efficient and secure graft stitching: Easy Whip. Check it out at…
Liked by Lia Winter
Experience & Education
Licenses & Certifications
Publications
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Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration
Nature Communications
While young muscle is capable of restoring the original architecture of damaged myofibers, aged muscle displays a markedly reduced regeneration. We show that expression of the “anti-aging” protein, α-Klotho, is up-regulated within young injured muscle as a result of transient Klotho promoter demethylation. However, epigenetic control of the Klotho promoter is lost with aging. Genetic inhibition of α-Klotho in vivo disrupted muscle progenitor cell (MPC) lineage progression and impaired myofiber…
While young muscle is capable of restoring the original architecture of damaged myofibers, aged muscle displays a markedly reduced regeneration. We show that expression of the “anti-aging” protein, α-Klotho, is up-regulated within young injured muscle as a result of transient Klotho promoter demethylation. However, epigenetic control of the Klotho promoter is lost with aging. Genetic inhibition of α-Klotho in vivo disrupted muscle progenitor cell (MPC) lineage progression and impaired myofiber regeneration, revealing a critical role for α-Klotho in the regenerative cascade. Genetic silencing of Klotho in young MPCs drove mitochondrial DNA (mtDNA) damage and decreased cellular bioenergetics. Conversely, supplementation with α-Klotho restored mtDNA integrity and bioenergetics of aged MPCs to youthful levels in vitro and enhanced functional regeneration of aged muscle in vivo in a temporally-dependent manner. These studies identify a role for α-Klotho in the regulation of MPC mitochondrial function and implicate α-Klotho declines as a driver of impaired muscle regeneration with age.
Other authorsSee publication
Patents
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Method and Apparatus for Double Loop Stitching
Issued JP 7037702
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Método y Aparato Para Puntada de Doble Lazo
Issued MX 389225
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Method and Apparatus for Double Loop Stitching
Issued US 10,792,036
Honors & Awards
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University of Tennessee - Volunteer 40 Under 40
The University of Tennessee, Knoxville, Office of Alumni Affairs
The Volunteer 40 Under 40 recognizes forty alumni under the age of 40 who have excelled personally and professionally since completing their degree at UT Knoxville.
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3D Experience Works for Startups Pitch Battle - 1st Place
Dassault Systemès
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Next Big Thing Competition - 1st Place
The Memphis Society of Entrepreneurs
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Get Started Medical Pitch Competition - 1st Place
Innovate South
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Collegiate Inventors Competition - Finalist
National Inventors Hall of Fame
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Knoxville Startup Day - 1st Place
Innov865 Alliance
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Louisiana Startup Prize - 1st Place
Louisiana Prize Foundation
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Boyd Venture Challenge – Seed Funding Awardee
University of Tennessee - Anderson Center for Entrepreneurship and Innovation
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Next Top Entrepreneur Competition - 1st Place
University of Georgia
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Cardinal Challenge - 1st Place
University of Louisville
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Stu Clark Investment Competition - 1st Place
University of Manitoba
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Boyd Venture Challenge – Seed Funding Awardee
University of Tennessee - Anderson Center for Entrepreneurship and Innovation
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Federal Express Leadership Service Award - Haslam College of Business MBA Class of 2018
Haslam College of Business
Recognizes a member of the graduating MBA class who has distinguished themselves through excellence in scholarship, program service, and class leadership.
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MABE Translational Research and Innovation Award
University of Tennessee Department of Mechanical, Aerospace, and Biomedical Engineering
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Boyd Venture Challenge – Seed Funding Awardee
University of Tennessee - Anderson Center for Entrepreneurship and Innovation
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VolCourt Idea Pitch Competition 1st Place - Seed Funding Awardee
University of Tennessee - Anderson Center for Entrepreneurship and Innovation
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Outstanding Cellular Engineering Student of the Year
University of Pittsburgh - Swanson School of Engineering
Organizations
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Creative Destruction Lab - Wisconsin, Health & Wellness Accelerator Program
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Springboard Health Innovation Hub: Life Science Accelerator
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Tampa Bay Wave TechDiversity Accelerator
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ZeroTo510 Medical Device Accelerator Program
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Recommendations received
1 person has recommended Lia
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Thank you, Premier Inc. team, for recognizing VersaWrap® and awarding Alafair with a national contract. I especially appreciate all of you who've…
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🎉🎉 Exciting News! 🎉🎉 We are thrilled to announce that TYBR Health has reached a significant milestone on LinkedIn . We now have over 600…
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