Eduardo Hariton, MD, MBA

In Episode 3 of the "Brain Cancer Science Talk" series on #MissionGBM, we chat with John de Groot, MD (Division Chief of Neuro-Oncology, UCSF) about immunotherapies, the need for combination protocols, Focused Ultrasound, and necessary improvements to clinical trial design and Regulatory framework to advance the development of treatment options for #braincancer patients. #FUS #ImmunoOncology #GBM #Onward #Nof1onBehalfofAll

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This week's summary of newsworthy articles across obesity and metabolic care, from twenty30 health Elaine Chen at STAT on new studies to suggest GLP-1 health care costs have only begun to climb. Large employers are trying to limit the costs of the expensive new generation of weight-loss drugs, from POLITICO. Delayed gastric emptying and pulmonary aspiration following induction of anesthesia in patients using GLP-1 drugs is not an issue, as per JAMA. The Kaiser Family Foundation analyzed Medicare data from 2020; an estimated 7% of Medicare beneficiaries, or 3.6 million overall were candidates for for GLP-1 drug Wegovy. https://lnkd.in/e8qnje7g

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In a compelling discussion, Senan Ebrahim, MD, PhD, Founder & CEO of Delfina, joined Erin Gau, Co-Founder and COO of Charter, to shed light on the persistent maternal health crisis in the United States. Despite high healthcare spending, the crisis deepens, driven by gaps in prenatal support that became glaringly apparent to Dr. Ebrahim during COVID. Here are 3 key takeaways from their conversation: 💡 Innovative AI Solutions Learn how Delfina uses AI to provide personalized, proactive care to expectant mothers, aiming to improve outcomes and prevent emergencies. 💡 The Role of Employers Discover how simple changes in workplace policies can significantly support pregnant employees. 💡 The Future of Healthcare Explore how Delfina plans to expand its network and integrate further into employer-sponsored health plans, setting new standards in prenatal care. Read their full discussion on the Transform blog to uncover the potential of AI in transforming maternal health and watch the full video interview. (See link in comments 👇 ) Here's a sneak peek... #Technology #HumanResources #Benefits #HealthTech #MaternalHealth #AI #PrenatalCare #Innovation #FounderFriday

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“I went to medical school wanting to make a difference,” says Anterior (formerly Co:Helm) co-founder and CEO Abdel Mahmoud, MD. “But I quickly realized that how good you are as a clinician is less about your individual skill set and more about the ecosystem and tools you have, and the environments you’re in.” Powered by LLMs, Anterior was built to manage all the work that comes before clinical decision-making, as well as take on the administrative overhead plaguing the healthcare industry. In the U.S. alone, these costs represent billions of dollars a year — not to mention the time taken away from potentially lifesaving research. Hear more about how Anterior is reshaping healthcare with AI in our latest Founder Forward interview featuring Abdel Mahmoud and NEA Co-CEO Mohamad Makhzoumi: https://lnkd.in/gttThK7M #healthcare #ai #llm

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An ounce of #prevention is worth a pound of cure. #GLP-1s rule the healthcare market now, and is predicted by some to be a $100B market by 2030, and is likely here to stay for the long haul given the multitude of health benefits associated with weight lost. But if we truly want to tackle #obesity, we need to start thinking about what we should do for patients after they’ve lost weight. How can they keep the weight off, especially since weight rebound seems to be a common phenomenon post GLP-1 discontinuation? More fundamentally, how do we prevent weight gain in the first place? There are many people in situations in which weight gain isn’t a simple case of "letting yourself go". How can we keep these people from gaining weight and developing comorbidities that can dramatically increase their mortality rate? Read on to see how we at The Healthcare Syndicate think about life after GLP-1s and the innovations needed to advance weight gain prevention strategies: https://lnkd.in/g2sscVDd #healthcareinnovation #angelinvesting

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🤰✨Addressing Inequities in Maternal Care: The Mission of Delfina ✨🤰 "Seeing that patient's anguish and the feeling of letdown, it was a feeling that we had let her down." Learn about the heartbreaking stillbirth that Senan witnessed as a young physician that was the catalyst to Senan deciding to build Delfina. Tech issues on my end will not get in the way of this incredible episode with Senan Ebrahim, MD, PhD the incredible CEO and founder of Delfina! Excuse my lack of video here as we jump in and discuss his journey in using technology to improve global maternal health. He shares his inspiration for getting into healthcare, the challenges he witnessed in prenatal care, and the importance of data-driven clarity and certainty in healthcare. Senan also shares about his previous venture, Hicma Health, and the accomplishments he is proud of. Delfina is focused on solving the maternal health crisis by using data and AI to provide intelligent pregnancy care. One major challenge in the healthcare industry is the data infrastructure, which is often outdated and not interoperable. Delfina aims to provide a maximally interoperable platform that can pull in and deliver data to health plans and providers. The typical experience for a Delfina member includes onboarding through the app, tracking symptoms and vital signs, and engaging with human doulas. The goal is to empower pregnant patients and provide personalized care. Do you have someone you love, that would LOVE this sort of approach to pregnancy care? We cover a lot of ground 🏃‍♂️🏃‍♀️💨💨: 🔴Data-driven clarity and certainty are crucial in healthcare to provide better care for patients, Senan's previous venture, aimed to provide digital health solutions for refugees and vulnerable populations. 🟠Inequities in maternal care, particularly among Medicaid patients, are a public health crisis that needs to be addressed. 🟢Delfina is working to solve these inequities by partnering with Medicaid plans and community-based organizations. The data infrastructure in healthcare is a major challenge, and Delfina aims to provide a maximally interoperable platform to address this issue. 🟡Delfina uses AI and machine learning to improve outcomes in obstetrics and pregnancy care. 🟢The typical experience for a Delfina member includes onboarding through the app, tracking symptoms and vital signs, and engaging with human doulas. 🟤Delfina's future plans include deepening its impact, rigorously measuring outcomes, and scaling to reach every pregnant patient in the United States. Watch the entire episode Digital Health Heavyweights Podcast to hear me pick the brain of an empathetic and brilliant CEO and Founder, and learn about the incredible work that Delfina is doing to impact maternal care worldwide! ▶ https://lnkd.in/dgwD6PHU 👂 https://lnkd.in/dyt3Vvhs

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I'm honored to be featured in the Frist Cressey Ventures Summer Newsletter as their CEO Spotlight! At Visana Health, we’re revolutionizing women's healthcare with our value-based, tech-enabled clinical model. We’re seeing growing interest in value-based care tailored for women, focusing on unique clinical and cost drivers. However, there's still significant underinvestment in conditions that uniquely or disproportionately impact women, which drive nearly 1 in 5 commercial plan dollars. We’re on track to treat tens of thousands of women this year, creating a 'medical home for women' and enhancing both patient and clinician experiences through technology. Our impact is clear: 93% of women see clinically meaningful improvements within 3 months, with many experiencing complete symptom relief, while we also reduce the total cost of care. Thanks to Frist Cressey Ventures for highlighting our mission to improve women's health. Read more: https://buff.ly/3yPXk28 #womenshealth #valuebasedcare #virtualcare

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You have to admit that the headline "Digital health resilience leads to brilliance" by Rock Health is a bit cheesy but when you look at the amount raised and number of deals, the future sounds more optimistic in H1 of 2024 than in the H1 of 2023. If you look at the Leading Value Propositions and Clinical Indications table you can see a #1 Treatment of disease at $1.1B. In the Clinical Indications the top 4 investments are in #mentalhealth, #cardiovascular, #oncology and #weightmanagement & #obesity. The upcoming trend of Food-as-Medicine or Food Care shows strength with $200M investment in Foodsmart. "The digital health sector continues to demonstrate resilience and adaptability. Funding momentum (especially at the early stage) and the tapering of transition measures like unlabeled rounds hint that we might be returning to more “normal,” sustainable venture patterns." Read the whole report by clicking on the link below. #digitalhealth #mentalhealth #obesity #weightmanagement #AI #foodasmedicine https://lnkd.in/gPmX8dFn

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…and private equity wants in on the action. Well that makes sense 🙄 Turns out running a hospital is very, very hard. A 4.3% margin is not healthy, even for a non-profit. Payors and pharma continue to point the finger at these “rich” hospitals and complain about market consolidation, 340B, and any number of other phantom problems, but in reality most are just trying to survive. Many of these grievances are gaslighting in its purest form. Those making it work are focused on the basics. The strategic plan has highly pragmatic, common sense initiatives that return a tangible benefit with clear measurable targets as opposed to chasing trendy buzz words. They control labor and they control drug cost. On the pharmacy side, they deeply understand the economics and have an appropriately positioned business minded, strategic pharmacy leader. #pharmacist #pharmacy #hospitals #healthcare https://lnkd.in/g9d9VTcK

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Join me on The Doctor’s Farmacy as I sit down with two incredible experts, Vijay Pande, PhD and Daisy Wolf from a16z Bio + Health, to explore how AI is set to revolutionize healthcare. We dive deep into the world of cutting-edge tech, like wearable devices and AI diagnostics, making personalized medicine more accessible and effective than ever before. I truly believe in the transformative power of AI in healthcare. The synergy between doctors, patients, and AI holds immense potential to improve the health and lives of countless individuals. That's why I co-founded Function Health —to harness this powerful relationship and bring advanced diagnostics and treatments to those who need them most. Catch the full episode here: https://lnkd.in/gbgDSDKp

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I learned so much! Thanks FemHealth Insights for putting this report together.

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Tomorrow my monthly Across the Kidneyverse recap of headlines, funding, research and commentary goes out to 6,000 fellow explorers. This month we mark major milestones in transplant, biopharma M&A, promising drug candidates, frictions from CKCC payment cuts, lessons from RPA, and a number of startup financings you should have on your radars. What else should people know about? Drop your news, thoughts and questions in the comments below (and I'll give you a shout out!). 👇🏼 Find all past issues here: 📰 https://lnkd.in/egGsNwqs

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PRP is OUT; fertility financing is IN: Find out all the hot trends (and research) in the fertility space of late in our weekly roundup…   1/The WSJ tackles the global decline in fertility rates: “We suspect that this shift reflects broad societal changes that are hard to measure or quantify.” What about fertility struggles? It’s a huge (infertile) elephant in the room.🐘https://lnkd.in/eguaHD6E 2/Controversial platelet-rich plasma procedures *do not* improve egg yield after stims in women under 38 with a history of poor ovarian response (POR), according to an RCT for ESHRE by Dr. Andrés Reig. Our medical advisor Dr. Pietro Bortoletto of Boston IVF’s TL;DR? Stop doing it.https://https://lnkd.in/ewqNEwRd   3/Chronic stress during puberty could impact fertility, according to an ESE study. It’s based on putting rats in enclosed spaces for an hour every morning, so if you were just a lil stressed as a tween, you’re probs fine.😅https://lnkd.in/enth8Nda 4/Three-quarters of U.S. adults support using emerging technology to screen embryos during IVF for likelihood of developing certain health conditions. https://lnkd.in/er8mPW47 5/Researchers say genetic information from placental cells outside the embryo may not be that helpful. Sampling fetal cells is better. .https://lnkd.in/euJWDu8V 6/The reversal of Roe v. Wade combined with women delaying TTC, has led to a rise in venture-backed companies focused on financing fertility treatments, since many can’t afford them, but they can’t afford to wait. (Cc our partner Bundl Fertility and friends Sunfish.) https://lnkd.in/eU7mf8F9 7/Oof: Our lunch ‘n learn this week with reproductive lawyer Melissa Brisman touched on this.⚖️https://lnkd.in/egNH29Ya 8/The Mamas First Act could make doulas and midwives reimbursable through medicaid.👏https://lnkd.in/emJmzG87 9/Survey finds 8K women a month are getting abortion pills in states where it’s restricted or illegal.https://https://lnkd.in/er528nYt 10/There’s a millennial mother midlife crisis (M.M.M.C.) happening. It’s so important to talk about all the pressures on this parenthood journey.😭https://lnkd.in/esDM62uv 11/We have a must-read FREE newsletter that comes out on Fridays. Sign up here! ➡️ https://lnkd.in/eZBEYJwA

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Equinox is launching a $40,000 longevity membership, let’s talk about it… 1. Limited Biomarker Testing: Equinox offers just two biomarker testing panels per year which may not be sufficient and it’s yet another appointment you have to schedule and go out to a lab for to complete. 2. Inflexible Personal Training Schedule: Three hour-long personal training sessions per week at a fixed location that is offered is not ideal for those with unpredictable travel schedules. 3. Overwhelming Number of Meetings: 16 hours per week with a nutrition coach, sleep therapist, and masseuse is what is offered. This is a part-time job's worth of meetings, unrealistic for those with packed schedules and frequent travel. 4. Nutrition Advice Only: Just offering nutrition advice isn't enough for busy professionals who don’t have time to cook or meal plan, plus it’s another appointment to schedule with another person you have to share your story and goals with again. 5. High Opportunity Cost: $40,000 is a substantial financial commitment for a program that might not fit into a busy lifestyle nor can travel with you. Feedback from some readers: “When is anyone supposed to work or travel with that kind of schedule?" “I would have anxiety to make all those sessions and appointments." Better solution… 1. Comprehensive & Convenient Biomarkers: Partnered with top labs like Joi and Blokes, providing more frequent and comprehensive testing for continuous health insights where a phlebotomist can go to your location or you can use an at-home kit at your time convenience. 2. Flexible Workout Schedule: Up to 7 days of workouts that fit into your schedule and location. Advanced accountability system that notify me progress, ensuring you stay on track. 3. Integrated Wellness Coaching: Seamless integration into your life, providing essential wellness coaching without overwhelming your schedule. 4. Nutrition Support: Connects you with a meal prep service or personal chef to delegate nutrition tasks. Nutrition is delivered to you, made where you are, or travels with you. 5. Bettter ROI: A fraction of the cost of Equinox’s membership, offering a more customized wellness experience that adapts to your schedule and location. While Equinox’s program has some appealing aspects, it’s simply not practical for busy, traveling business leaders. My Solution: A program that is a fraction of this cost and offers a customized wellness experience that fits your schedule and location. You’ll achieve optimal health without sacrificing your lifestyle. The timing of this is quite funny as I recently created a free guide for longevity specifically for business leaders 40+ like myself. If you’d like it, let me know. Thanks for taking the time to hear me out. I genuinely believe we can make your health journey fit smoothly into your busy life. Free consult: https://lnkd.in/eNfD88Xk

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Unlearn, Unbadge, Unframe As someone who has spent the last 15 years honing my skills and knowledge in clinical trials, whenever approached for advice on mastering them, I consistently offer three insights drawn from personal experience. Here they are: Unlearn: Clinical trials, like all other specialties in medicine, possess their own unique language and rules of engagement. The lesser we resist, the faster we can master the trade. Embrace terms like SIV, SMV, COV, and others. Let go of preconceived notions and open yourself to new ways of understanding. Unbadge: Time to park that ego and title aside. Be a student, learn from your experienced colleagues and study coordinators, regardless of seniority. Their insights are invaluable on the journey to mastering clinical trials. Unframe: Adopting a change of mindset is crucial. While in clinical medicine, we often navigate comfortably within the gray areas, clinical trials demand a shift to a black-and-white paradigm. Assessing the safety and efficacy of novel compounds requires precision and clarity. Adapting to this new reality can be challenging, but it's essential for success in clinical research. Let’s share our knowledge about clinical trials so together we can educate and increase awareness of clinical trials amongst our medical peers, encouraging them to integrate them into their repertoire of treatment options. By sharing our experiences and insights, we can collectively advance medical innovation and enhance patient care. #ClinicalTrials #MedicalResearch #HealthcareInnovation #ABBEConsulting This photo takes me back to my presentation at Malaysia's National Conference for Clinical Research, where I shared my journey from clinical medicine to clinical trials to inspire junior doctors to consider research career. Titled 'Finding My Niche,' it was during this session that I first introduced the advice 'unlearn, unbadge, unframe.' A memorable day indeed, for me at least 😉 +++++++ Hi, I’m Dr. Stephanie Tan. I share stories about embracing #change, navigating the intersection of medicine and corporate, and balancing #motherhood with a fulfilling career. Like and follow my profile for posts on being a #workingmom, navigating #careertransitions, and the intersection of #medicineandindustry.

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I constantly encounter these challenges among healthcare professionals: (Check if you're not one of them) "I find it hard to maintain work-life balance." "I struggle to keep up with industry changes." "I feel overwhelmed by the demands of my job." "I'm too busy to focus on personal development." "I'm not sure how to expand my professional network." Here's how we can tackle these together, leading to enhanced satisfaction and efficiency, without overextending ourselves: 1st, we focus on efficient time management: 🤝 We team up to identify and eliminate time-wasters 🚀 This leads to more productive days and less burnout Then, we prioritize self-care and professional growth. 2nd, we embrace continuous learning: 🤝 We partner to stay abreast of the latest in healthcare 🚀 It results in staying competitive and feeling fulfilled And we commit to ongoing development. 3rd, we strengthen networking skills: 🤝 We collaborate to build and nurture professional relationships 🚀 It opens new opportunities and enhances collaboration And we maintain these connections for lasting support. How do you tackle these challenges in your professional life? Let me know in the comments! P.S. Follow me, ring the 🔔 in my profile Don’t miss my next post!

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A fantastic panel of pain physicians and digital health entreprueners on the role of "Digital Pain Management" in patient care moderated by HealthXL Key Takeaways.. 👇👇 👉 Evidence driven Digital Pain Management tools have a big role to play both at bedside and at home to reduce opioid use. 👉 Digital Pain Management tools also help monitor and measure pain objectively. 👉 It's important Digital Pain Management tools conduct proper Randomized Clinical Trials (RCT) and go through FDA review for wider physician adoption. #painmanagement #opioids #painmedicine #digitalhealth #digitaltherapeutics

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a16z Bio + Health doubles down on healthcare and invests in Function Health In 2022 Andersen Horowitz made the decision to dive into healthcare - because they believe that the biggest company in the world will be a consumer health tech company. This year, A16Z invested in Function Health as the lead in its Series A.  Since launching its beta in 2023, Function Health has amassed 50,000 members - with no marketing.  It boasts a strong founding team, that including Dr. Mark Hyman Ed.D. as its Chief Medical Officer.  Earlier this year, Function announced its partnership with Equinox.  It has raised a total of $53M. A16Z’s investment in Function might come as a surprise to some but it has made no secret of its bet in tackling consumer healthcare. The US Healthcare industry is massive ($4 trillion USD and 20% of GDP) - which is why A16Z, along with every large tech company (Google, Apple, Facebook, Amazon) are moving towards it.  They are also moving towards it because the current largest healthcare company in the world is not a tech company and does a poor job in consumer engagement.  UnitedHealth Group (UHG) is the 19th largest company in the world and the largest healthcare company with a market cap of $450B (not including Eli Lilly and Company and Novo Nordisk).  UHG by all metrics is technically a consumer company with half of its sales being DTC - yet their consumer engagement is extremely poor with a NPS of 4. A consumer health company’s core competency should be their ability to engage and retain patients - something that most healthcare companies have failed to do historically. The healthcare industry is ripe for a consumer-obsessed, healthcare-native tech company that will reimagine what care can look like.  A consumer health company will win by placing consumers first, while still taking into account the realities of payor and provider incentives. As per A16Z, “Function started a movement and has fundamentally changed consumer behavior. ..it’s a preventative, lifelong approach to health, not just a single event or doctor’s visit. It’s a new routine that enables people to catch health issues early and benefit from AI advancements. Traditional healthcare treats symptoms; Function finds root causes.” - all for $499 / year. Where do you think the biggest opportunity for innovation exists in healthcare?  Let me know below. 👇 #a16z #healthcare #innovation #funding #function #fitness #wellness #digital #disruption #consumer #payor Vator SweatWorks

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Function wants to reimagine healthcare. The preventative diagnostics platform closed a Series A investment led by a16z Bio + Health, bringing its total funding to $53M. Co-founded by functional medicine expert Mark Hyman, MD, the company leverages robust lab testing to improve longevity and healthspan. Taking a proactive approach, twice-annual 100-biomarker panels are reviewed by AI and human clinicians to spot and treat disease. Members can also opt for additional tests as needed. Operating in beta since April, Function Health counts 50K paying customers, a 200K person waitlist, and recently partnered with Equinox. Losing faith in traditional healthcare, more people are seeking preventative scans, alternative medicine, and longevity protocols. Democratizing diagnostics, Function wants to prioritize health over healthcare. 

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