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Sweet-and-Sour Pork Tenderloin

4.9

(42)

Image may contain Dish Food Meal Platter Salad and Plant
Photo by Chelsea Kyle, Food Styling by Pearl Jones

The tangy, mouthwatering sauce here is inspired by agrodolce, an Italian sweet and sour sauce made by reducing vinegar, sugar, and spices. It's pretty much always delicious, but here we build the sauce in the same pan that we seared the pork, giving it even more richness and flavor. Let's talk about pork tenderloin for a second. This crowd-pleasing cut sometimes gets a bad rap for being dry, but that's just because most people overcook it. Whatever you've been told before, 140° is the internal temperature you're looking for here—the meat will still be a bit pink, but it's totally safe to eat and will be unbelievably juicy.

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What you’ll need

Recipe information

  • Yield

    4 servings

Ingredients

2

pork tenderloins (about 2 lb. total)

1

tsp. freshly ground black pepper

3

tsp. kosher salt, divided

2

medium red onions

1

medium head of red leaf lettuce

1

large fennel bulb (with stems and fronds)

3

Tbsp. cold unsalted butter

5

Tbsp. extra-virgin olive oil, divided

5

Tbsp. honey

1

tsp. crushed red pepper flakes

1

cup plus 1 Tbsp. red wine vinegar

Preparation

  1. Step 1

    Pat 2 pork tenderloins (about 2 lb. total) dry with paper towels. Season all over with 1 tsp. black pepper and 2 tsp. salt. Let sit at room temperature until ready to cook.

    Step 2

    Meanwhile, do some prep. Halve 2 medium red onions through the core. Trim off ends, peel, and slice into ½"-thick wedges lengthwise. Transfer to a medium bowl and set aside.

    Step 3

    Wash and dry 1 medium head of red leaf lettuce, then tear into bite-sized pieces. Transfer to a large bowl.

    Step 4

    Tear off nice looking fronds from 1 fennel bulb and transfer to bowl with lettuce. Trim a few inches from tops of stems, then remove stems from bulb. Cut bulb in half lengthwise and remove core. Thinly slice stems and bulb crosswise and add to bowl with lettuce. Chill until ready to use.

    Step 5

    Cut 3 Tbsp. cold unsalted butter into small pieces. Chill until ready to use.

    Step 6

    Heat 2 Tbsp. extra-virgin olive oil in a large skillet over medium-high until shimmering. Sear tenderloins until golden brown on each side, about 2 minutes per side, 6–8 minutes total.

    Step 7

    Using tongs, transfer pork to a plate. Cook onion, 1 Tbsp. extra-virgin oil, and ½ tsp. salt in same pan in a single layer over medium-high heat, tossing occasionally, until well browned and beginning to soften, about 5 minutes.

    Step 8

    Whisk 5 Tbsp. honey, 1 tsp. red pepper flakes (if you don’t like things spicy, cut the amount of red pepper in half, but we really love how the spiciness balances the sweetness here), 1 cup red wine vinegar, and ¼ cup water in a glass measuring cup and add to pan. (Make sure you get all that honey!) Bring to a simmer.

    Step 9

    Return pork to pan and cook, turning every 5 minutes and reducing heat as needed to keep sauce at a low simmer, until an instant-read thermometer inserted into the thickest part of the meat registers 140°, 12–20 minutes. (Start testing for doneness after 10 minutes; pork will cook differently depending on the size of the tenderloin you're working with. It’s important to use a thermometer in this case because it’s very easy to overcook a lean cut like this, and nobody likes dry pork!) Transfer pork to a cutting board to rest. This will lock in all the juices and let the pork continue to cook just a bit.

    Step 10

    Continue to cook sauce, stirring occasionally, until thick and syrupy, 3–5 minutes. Remove from heat and stir in cold butter with tongs until fully incorporated.

    Step 11

    Add remaining 2 Tbsp. extra-virgin olive oil, 1 Tbsp. red wine vinegar, and ½ tsp. salt to salad and toss to combine.

    Step 12

    Slice pork tenderloin on a diagonal. Divide among plates and spoon agrodolce sauce over. Serve salad alongside.

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Reviews (42)

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  • Fast, easy and tasty, but I prefer to dry brine pork with salt and fresh herbs a day in fridge and I ad pepper a sometimes cumin before browning. Also good with roasted squash.

    • M.E. Hungry

    • 2/4/2024

  • Really tasty. That onion reduction takes a lot longer than a few minutes. Keep it low and slow tho.

    • Shazziz

    • NYC

    • 5/7/2023

  • Amazing! So flavorful! I will make again for sure. Also, I used the recommended amount red pepper flakes, and did not find it too spicey

    • Anonymous

    • St. Louis

    • 4/17/2023

  • Forgot the butter and it was still delicious! Easy, light, tangy!

    • Anonymous

    • Denver CO

    • 7/20/2022

  • I’ve made this dish five or six times now and each time it’s a huge hit. I sent the link to a family member who agreed this is one of the best dishes she’s made in a long time. I end up serving it over jasmine rice and a side of sautéed cabbage. 1/10 recommend

    • Kristina

    • Tampa, FL

    • 3/20/2022

  • Amazing! I had some pork tenderloin at hand and was looking for a recipe with a sauce different from the classic roast the first time I tried it. This was perfect. My entire family, including my mom, who stubbornly tries new dishes, loved it. It tastes even better the day after or cold straight from the fridge. I would consider increasing the sauce amount. It’s that good. Only issue with the recipe is that it takes waaaayyyy longer than indicated to reach the sauce’s syrupy consistency. To avoid this, I would recommend increasing the temperature a bit. I have an electric stove, so that might be the reason for this. Otherwise, a recipe I go back to time and time again.

    • Anonymous

    • San Juan, Puerto Rico

    • 2/21/2022

  • The onion sauce is the main star here, and it's incredible. Others mentioned the flavors not permeating the pork, and I have to agree. That being said, I did get a nice, tender pork tenderloin cooking according to recipe. Once smothered with the jammy onion sauce, it's a sweet and tangy flavor punch with a nice kick at the finish (I used a heaping tsp of red pepper flakes).

    • Anonymous

    • Richmond, Virginia

    • 9/2/2021