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Randomized Controlled Trial
. 2017 Oct 10;318(14):1391-1392.
doi: 10.1001/jama.2017.11152.

Effects of Behavioral Interventions on Inappropriate Antibiotic Prescribing in Primary Care 12 Months After Stopping Interventions

Jeffrey A Linder  1 , Daniella Meeker  2 , Craig R Fox  3 , Mark W Friedberg  4 , Stephen D Persell  1 , Noah J Goldstein  3 , Jason N Doctor  2
Affiliations
Randomized Controlled Trial

Effects of Behavioral Interventions on Inappropriate Antibiotic Prescribing in Primary Care 12 Months After Stopping Interventions

Jeffrey A Linder et al. JAMA. .

Abstract

This study examines assesses inappropriate antibiotic prescribing 12 months after stopping a randomized clinical trial of a behavioral intervention intended to reduce the rate of inappropriate antibiotic prescribing for acute respiratory infections.

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Conflict of interest statement

Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Linder reported an honorarium from the Society of Healthcare Epidemiology of America (SHEA) as part of the SHEA Antimicrobial Stewardship Research Workshop Planning Committee, an educational activity supported by Merck. Dr Persell reported grant funding from Pfizer and personal fees from Omron Healthcare. Dr Doctor reported consulting fees from Precision Health Economics. No other disclosures were reported.

Figures

Figure.
Figure.. Adjusted Rates of Antibiotic Prescribing for Antibiotic-Inappropriate Acute Respiratory Tract Infection Visits by Intervention
Antibiotic prescribing rates at primary care office visits over time for each intervention are marginal predictions from hierarchical regression models of intervention effects, adjusted for concurrent exposure to other interventions and clinician and practice random effects. Error bars indicate 95% CIs. Interventions started at day 0 and ended at day 540. The plot in Panel A differs slightly during the intervention period from Panel 2 of the study by Meeker et al due to attrition of 5 clinicians, who were not included in this analysis.
See this image and copyright information in PMC

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References

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