Brian Kennedy

Dietary protein and amino acid intakes for mitigating sarcopenia in humans https://lnkd.in/g6nnpjDN

4

A research team from the National University of Singapore (NUS) has unearthed new findings which may help explain the connection between #cancer RISK and poor #diet, as well as common diseases like #diabetes, which arise from poor diet. The study was conducted by scientists from the Cancer Science Institute of Singapore (CSI Singapore) at NUS and NUS Centre for Cancer Research (N2CR) under the NUS Yong Loo Lin School of Medicine, with colleagues from the A*STAR - Agency for Science, Technology and Research (A*STAR). The research team first studied patients who are at a high risk of developing #breastcancer or #ovariancancer because they inherit a faulty copy of the cancer #gene -- #BRCA2 -- from their parents. They demonstrated that cells from such patients were particularly sensitive to the effects of #methylglyoxal, which is a chemical produced when our cells break down #glucose to create energy. The study showed that this chemical can cause faults in our DNA that are early warning signs of cancer development. The team's research also suggested that people who do not inherit a faulty copy of BRCA2 but could experience higher-than-normal levels of methylglyoxal -- such as patients with diabetes or pre-diabetes, which are connected with obesity or poor diet -- can accumulate similar warning signs indicating a higher risk of developing cancer. The NUS team found that methylglyoxal can temporarily inactivate cancer-preventing genes, suggesting that repeated episodes of poor diet or uncontrolled diabetes can 'add up' over time to increase cancer risk. This new knowledge is likely to be influential in changing the direction of future research in this area. https://lnkd.in/eN3DMwwc

23

FAQ: How to identify mushrooms growing around my house? Answer: Consult our international experts at MycoAsia-Fungi ID, https://lnkd.in/gqaNtPrA MycoAsia Journal of Modern Mycology

8

The study focused on the anxiolytic potential of clove volatile oil (CVO) and its primary compound, eugenol (EUG), which has low bioavailability. CVO was encapsulated in nanosystems using Agaricus blazei Murill polysaccharides as a stabilizing agent to overcome this limitation. The study found that CVO-NE reduced the anxious-like behavior of adult zebrafish without affecting locomotor activity. The anxiolytic activity of CVO, EUG, and CVO-NE was linked to the involvement of the GABAergic pathway. The study demonstrates the anxiolytic effect of CVO and provides a new nanoformulation for its administration.

11

1 Comment

🥁 Paper sharing from Frontiers in Bioscience-Landmark 📖Transcriptome and Pathway Analysis Reveals that Adipose-derived Stem Cells Target Inflammatory Factors and Delay the Progression of Diabetic Liver Disease 🔗https://lnkd.in/gxdbYSuN #CellBiology #Metabolism #Bioscience #Diabetic liver disease #adipose-derived stem cells

3

❗ Asparagus-based scaffolding breakthrough could boost #cultivatedmeat production ❗ 🌱 Researchers from Singapore's A*STAR - Agency for Science, Technology and Research have developed a novel technology that uses asparagus to create an edible scaffolding structure for cell-based meat production 🦠 Asparagus is rich in cellulose, hemicellulose and other polysaccharides that can be leveraged to create a highly functional biomaterial scaffold 🗣 Lily Heng, lead author of the study, said: "Asparagus has a naturally fibrous and porous structure that provides an excellent growth matrix for muscle and fat cells. The plant's biochemical composition also contains various proteins, vitamins, and minerals that can support cellular proliferation and differentiation."  ♻ "The edible and biodegradable nature of the asparagus scaffold means it can be seamlessly integrated into the cultivated meat matrix, providing a truly 'green' and consumer-friendly solution" 🧫 Read more on the fully edible and biodegradable scaffolds on The Cell Base 👇 #culturemedia #scaffold #ediblescaffold #meatscaffold #altprotein #cellbasedmeat #culturedmeat #Singapore #novelfood #cellag https://lnkd.in/g8sZ6wga

17

Made the trip down to National Cancer Centre Singapore earlier today for an enlightening sharing by Prof. Fan Rong (Yale University) and co-hosted by Singleron APAC! Interesting takeaway - Although Th1 T cells are considered to be the main player for #CAR-T cancer #immunotherapy, the underappreciated Th2 T cells turn out to be indispensable for long-term efficacy and preventing relapse. Today's problems are often multidisciplinary in nature. Solving them will require us to be like the T cells - coming together with our diverse expertise and skillsets to create new solutions. As we deal with the challenges of today, let's remember not just to go at it alone, but also leverage each others talents for a better tomorrow.

40

What Consumers in Vietnam Think About Gene-Edited Rice Researchers from Vietnam National University and partners from Japan assessed the consumer acceptance of consumer-targeted gene-edited products, particularly gene-edited rice with improved quality. They explored the factors influencing their choices and how much they are willing to pay for gene-edited rice compared to regular or GM rice. Consumers in Vietnam were chosen as respondents because of low misinformation about gene editing on social media platforms in the country. The findings showed that consumers will likely embrace gene-edited foods with better taste and nutrition, especially if they can access clear information about the technology. This may imply that gene editing could be a game-changer for creating tastier and healthier food options that people actually want to buy, especially in Vietnam https://lnkd.in/enQ-3eTg Read the full text at: https://lnkd.in/eY__K_XD

1

Illinois ARCS, a University of Illinois Urbana-Champaign-affiliated research center in Singapore has launched the new program "Centre for Precision Fermentation and Sustainability” (PreFerS). The five-year, S$20M program led by Prof. Yong Su-Jin, with collaborators from National University of Singapore, Nanyang Technological University Singapore, Singapore Institute of Technology, and A*STAR - Agency for Science, Technology and Research will focus on enhancing the reliable, cost-effective production of safe, nutritious, and appetizing foods. More specifically, the research will advance technologies for microbial cell engineering — creating metabolic pathways in microorganisms — to convert readily available compounds like sugars into targeted, nutritional molecules including alternative proteins, healthy lipids, and vitamins. https://lnkd.in/gEBw6uc2

6

What do beetles, termite mounds, and elephant skin have in common? For Good Design Research (GDR) recipient biosea.sg, these are inspiring examples of nature’s ingenuity for climate control.  With the support of DesignSingapore Council’s GDR grant, bioSEA founder Dr Jain and his team further explored biomimicry – that is to learn from and adopt strategies found in nature – through their research. The Biomimicry Design Toolkit which they’ve developed as a result, reflects how existing buildings around the world have emulated nature’s forms to stay cool.  But they didn’t stop there. Drawing inspiration from real-world examples, they’ve crafted innovative prototypes for building “skins”. Imagine textured clay-mycelium tiles for passive cooling inspired by an elephant’s skin, water-condensing walls that reference the Namib Desert Beetle’s bumpy back, and even breathable bricks that regulate humidity, just like termite mounds.     Kickstart your design idea through research with the support of GDR today: bit.ly/Dsg-GDR.     #GoodDesignResearch #DesignSingaporeCouncil #DesignImpact     –  The Good Design Research (GDR) initiative by the DesignSingapore Council supports design and non-design companies in building a practice of design research to strengthen business sustainability and drive impactful innovation. Now open year-round for applications.

38

1 Comment

“A groundbreaking study by Yunha Hwang and team has developed gLM, an AI system that decodes the complex language of genomics from extensive microbial data. This innovation enables a deeper understanding of gene functions and regulations, leading to new discoveries in genomics. gLM exemplifies the potential of AI in advancing life sciences and tackling global challenges” #microbiome #ai #ml #microbial #data Ross’ comment: Biosortia obtains extensive microbial data and molecules from natural microbiomes. See also: https://lnkd.in/dMReRRsa https://lnkd.in/g6dkbRXj

30

1 Comment

🌍🏆Check out this interview video featuring Dr. Maarten van Zonneveld, Head of Genetic Resources at the World Vegetable Center. This international research team, in collaboration with CIFOR-ICRAF and National Taiwan University sheds light on the potential of 'forgotten' food crops in sub-Saharan #Africa to address dietary challenges in the face of climate change. Their groundbreaking research won the Cozzarelli Prize. Learn about the 58 #nutrient-rich crops identified to enhance diets amidst climate change. Watch now for insights on revolutionizing cropping systems! #CozzarelliPrize #ClimateChange #Nutrition 🌱🍲

3

Delighted to share that my latest review on Monkeypox, crafted under the expert guidance of Dr. Balram Omar , has just been published! 📝🔬 Explore the fascinating journey of Monkeypox from pandemic to endemic status in this comprehensive review. Curious to learn more? Dive into the details here: https://lnkd.in/gSG-3msc Let's continue pushing the boundaries of knowledge together! 🚀 #Monkeypox #Research #Healthcare #Publication #Science

31

4 Comments

#Cultivatedmeat sector.. what’s next? Happy to share some insights and thoughts along with few industry partners with The Straits Times. Certainly a topic worth thinking about, that closely relates to our sustainable future. Are there an immediate need just yet? Might not. Will we need the technology in the future? What do you think. #sustainability #cultivatedfat #omega3

52

1 Comment

Check out this article: https://lnkd.in/gyyjZePV titled “Improvement in autonomic balance through 12-week supplementation of a novel curcumin formulation in healthy Japanese adults: A randomized, placebo-controlled study” in our journal Functional Foods in Health and Disease. This article is written by Kuwabara Yoshitaka, Hyunjin Lee, Akiko Hirose, Yuji Makino, Kyohei Hashimoto, Misaki Sakata, and Tadashi Watanabe. Curcumin has several health benefits due to its potent antioxidant and anti-inflammatory properties, but its bioavailability is very low, limiting its potential. We have developed a novel curcumin formulation, TS-P1, which has an 85.2-fold higher bioavailability of curcumin than raw curcumin. These data suggest that TS-P1 induced a parasympathetic dominant state, and that curcumin has an important role in the regulation of autonomic balance. 12 weeks of supplementation of TS-P1 is expected to improve both mood status and vascular function. Follow our LinkedIn page at https://lnkd.in/g-8YYvHB Email: editor@ffhdj.com Sincerely, Functional Food Center

2

1 Comment

Our new study analyzing the multifaceted aspects of dietary habits and experiences related to healthy food choices in Japan is out. Please take a look https://lnkd.in/gdCh9UTP

3

On May 11, 2024, #BGI-Research along with South China Agricultural University, China Pharmaceutical University, and Nanjing University of Chinese Medicine, published a ground-breaking study in Nature Communications. This research unveiled the genetic intricacies of Chachi mandarin (Citrus reticulata cv. Chachiensis), a cornerstone in traditional Chinese medicine for over 700 years. The team utilized advanced multi-omics technologies to map the Chachi mandarin genome. Key findings include the discovery of a new gene that helps the fruit make a substance which can potentially fight cancer and reduce inflammation. This highlights the fruit's potential in medicinal applications and emphasizes the importance of genetic research in understanding and harnessing the properties of medicinal plants. The study not only deepens our understanding of the genetic basis for the medicinal properties of Chachi mandarin but also sets the stage for future applications in genome-assisted breeding and quality improvement of medicinal plants. These insights pave the way for enhanced cultivation techniques and could significantly impact the field of medicinal plant research. Read more: https://bit.ly/44G50Qd

4