See you tomorrow in Hamburg for #ISSCR2024! Come by our booth #903. We would love to learn more about your research and discuss how our full-length Biolaminin® matrices can support your cell culture. Here are some activities we have for you: 🌟 Thursday, July 11 from 3:45 to 4:45: Poster #269:“Gene editing cells using CRISPR-Cas9 on Biolaminin® 521 improves single-cell survival and cloning, enabling consecutive differentiation of human pluripotent stem cells on biorelevant matrices” 🌟 Thursday, July 11 from 4:45 to 5:45: Poster #254: “Organ-specific expression data steer choice of laminin proteins for in vitro studies, for biologically relevant drug discovery and development platforms” 🌟 Thursday, July 11 from 6:00 to 6:30 Don't miss our Innovation showcase: “Biolaminin® technology: supporting standardization for translational success”- Dr. Brian Hawkins, from Pluristyx, Inc., and Dr. Terri Gaskell, from Rinri Therapeutics Ltd., will share their stories of translational success. Dr. Ilse Eidhof, from Lund University/ Karolinska Institute, will share how defined culture conditions robustly maintain human stem cell pluripotency via tightly controlled Ca2+ signaling. Pre-register now for our innovation showcase ➡ https://lnkd.in/dsgtQEX9 🌟 Friday, July 12 from 3:45 to 4:45: Poster #363: “Full-length laminins are crucial for recreating the cellular niche in vitro“ 🌟Friday, July 12 from 4:45 to 5:45: Poster #408: “Recombinant laminin proteins provide a biologically relevant niche for primary cells in vitro, mimicking the natural niche for both adult stem cells and cancer cells” Bis bald!
BioLamina
Forskning inom bioteknik
Cell-specific culture matrices for improved cell functionality
Om oss
BioLamina is a Swedish biotechnology company with a global presence, offering cell culture matrices for primary cells. We offer an expansive portfolio of recombinant laminin proteins for a variety of applications, including the reliable expansion of pluripotent cell and differentiation and maintenance of specialized cell types. Our chemically defined and xeno-free laminin cell culture matrices allow you to imitate the natural cell-matrix interaction in vitro. Laminins are key components of the extracellular matrix. Through their interactions with specific receptors, laminins trigger the authentic cellular responses, pivotal for cell anchorage, survival, proliferation, migration, organization, and specialization, leading to improved cell functionality. BioLamina’s laminins are the only original full length, human, recombinant laminins on the market. Our high technology products contribute to our customer’s efficiency and scientific breakthroughs and enable them to start a new era in medical research. We are known and recognized for our premium products, competence, dedication, and service and position ourselves as being in the forefront of cell culturing. Our vision is to make BioLamina a leading brand within the field of cell culture and to help make cell therapy a reality. BioLamina is built on a scientific foundation with a legacy in matrix biology and solid experience in cell culture-based research. The company was started in 2009 and was co-founded by Dr. Karl Tryggvason and his son Dr. Kristian Tryggvason. Today the company has about 35 employees spanning from production, R&D, logistics, sales, and marketing. Our quality system complies with ISO 9001:2015 and both management and employees follow well-defined standard processes and agreements.
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http://www.biolamina.com
Extern länk för BioLamina
- Bransch
- Forskning inom bioteknik
- Företagsstorlek
- 51–200 anställda
- Huvudkontor
- Sundbyberg
- Typ
- Privatägt företag
- Grundat
- 2009
- Specialistområden
- Cell culture, Stem cell culture and differentiation och Laminin
Adresser
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Primär
Löfströms Allé 5
Sundbyberg, 17266, SE
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One Broadway
Cambridge, MA 02142 , US
Anställda på BioLamina
Uppdateringar
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Fascinating results just published in Developmental Cell demonstrate the foundational role of laminins in stem cell maintenance and differentiation in early embryos. The results of this study align with the widely accepted view that full-length laminin: ➡ is the first and founding component of the crucial supportive layer that guides cell development: the basement membrane ➡once produced, directly binds to cell surfaces and builds an independent network via self-assembly ➡ regulates cell differentiation and tissue development already early in development. Rosner and Hengstschläger examined how the basement membrane forms and breaks down during in vitro embryo development. They identify key structural components and receptors within the BM and demonstrate the importance of Oct4 in regulating BM development, including laminin assembly. Read the publication ➡ https://lnkd.in/dGb-zUdj 𝑃𝑖𝑐𝑡𝑢𝑟𝑒 𝑑𝑒𝑠𝑐𝑟𝑖𝑝𝑡𝑖𝑜𝑛: 𝑂𝑐𝑡4 𝑎𝑓𝑓𝑒𝑐𝑡𝑠 𝑙𝑎𝑚𝑖𝑛𝑖𝑛 𝑎𝑠𝑠𝑒𝑚𝑏𝑙𝑦 𝑑𝑢𝑟𝑖𝑛𝑔 𝑖𝑛 𝑣𝑖𝑡𝑟𝑜 𝑒𝑚𝑏𝑟𝑦𝑜𝑔𝑒𝑛𝑒𝑠𝑖𝑠. 𝐶𝑜𝑛𝑓𝑜𝑐𝑎𝑙 𝑖𝑚𝑎𝑔𝑒𝑠 𝑠ℎ𝑜𝑤𝑖𝑛𝑔 𝑜𝑟𝑡ℎ𝑜𝑔𝑜𝑛𝑎𝑙 𝑝𝑙𝑎𝑛𝑒𝑠 𝑜𝑓 𝑐𝑜𝑛𝑡𝑟𝑜𝑙- 𝑎𝑛𝑑 𝑂𝑐𝑡4-𝑑𝑒𝑝𝑙𝑒𝑡𝑒𝑑 𝑒𝑚𝑏𝑟𝑦𝑜𝑖𝑑𝑠 𝑖𝑛 𝑡ℎ𝑒 𝑒𝑥𝑝𝑒𝑟𝑖𝑚𝑒𝑛𝑡𝑎𝑙 𝑠𝑒𝑡𝑡𝑖𝑛𝑔𝑠 𝑑𝑒𝑠𝑐𝑟𝑖𝑏𝑒𝑑 𝑖𝑛 𝑡ℎ𝑒 𝑝𝑢𝑏𝑙𝑖𝑐𝑎𝑡𝑖𝑜𝑛 𝑏𝑦 𝑅𝑜𝑠𝑛𝑒𝑟 𝑎𝑛𝑑 𝐻𝑒𝑛𝑔𝑠𝑡𝑠𝑐ℎ𝑙𝑎̈𝑔𝑒𝑟, 2024 𝐷𝑒𝑣𝑒𝑙𝑜𝑝𝑚𝑒𝑛𝑡 𝐶𝑒𝑙𝑙.
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Pluripotent stem cell (#PSC)-derived #cardiomyocytes play a key role in therapies of the future, serving directly as cellular therapy, as source material for tissue-specific extracellular vesicles, and as a platform for drug development. This requires standardized, reproducible, and efficient derivation of cardiomyocytes. This application note describes a published method on how to derive #xenofree and defined cardiovascular progenitor (CVP) cells and cardiomyocytes (CM) at high efficiency with a combination of Biolaminin® 521 and #Biolaminin 221 substrates (Lynn Yap et al. 2019 and 2023). The method is twice as efficient as other standardized substrates. The cells mature and display critical functional features, such as contraction and electrophysiological signatures, improving heart function over time after successful integration into infarcted pig hearts. Learn more about it ➡ https://lnkd.in/dVmrrZPs
Cardiomyocyte differentiation on combination of full-length Biolaminin® 521 (LN521) and Biolaminin 221 (LN221) substrates
biolamina.com
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Don't miss our Innovation showcase at #ISSCR2024 on July 11 from 6pm with Dr. Brian Hawkins from Pluristyx, Inc., Dr. Terri Gaskell from Rinri Therapeutics and Dr. Ilse Eidhof from Karolinska Institutet / Lund University. Do you want to pre-register and get reminders before the show? Click here ➡ https://lnkd.in/dsgtQEX9
Current testing strategies are insufficient for the comprehensive genetic characterization of iPSC starting materials. Join our Chief Technology Officer, Dr. Brian Hawkins, as he reviews Pluristyx, Inc.'s efforts to detect low-level incidences of genetic abnormalities and minimize risk for clonal outgrowth in manufactured GMP banks. We look forward to meeting at #ISSCR2024 to discuss how Pluristyx is helping to raise the bar to deliver the next generation of iPSCs for clinical development. 💠 July 10: Genetic Whack-a-Mole: Battling Instabilities in iPSCs 💠 July 11: BioLamina's BioLaminin® Technology: Supporting Standardization for Translations Success #RegenerativeMedicine #celltherapy #iPSCs #stemcells
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💡Did you know that full-length laminins are crucial components in creating the stem cell niche in vivo and in vitro? 🔬 Laminin proteins play a crucial role in the development and maintenance of healthy tissues, and their expression patterns are tightly regulated both spatially and temporally. Without the right combination of laminin isoforms, cells and tissues become dysfunctional. ✍ Full-length laminins are an essential part of creating the stem cell niche, guiding cell identity, survival, and migration through actively binding: ➡ Cell surface receptors, activating stem cell critical pathways. ➡ ECM components, creating basement membrane and cellular polarity. ➡ Growth factors, acting as a growth factor reservoir modulating microenvironment. 🌟 Learn more about it in our newest Application Overview ⏩ https://lnkd.in/dqy2CZCr Attending #ISSCR2024? Meet our team at booth 903. We would love to learn more about your research and discuss how our full-length Biolaminin® matrices can support your cell culture. #BioLamina #laminin #gofulllength #Biolaminin #cellculture
BG-008_Full-length-laminin-proteins-are-crucial-for-stem-cells.pdf
biolamina.com
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Today is #Midsommar, a very popular festival in Sweden. Families and friends meet and enjoy celebrating the summer solstice. We wish you all a very happy Midsummer. Glad Midsommar! #BioLamina
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These last two days, we were thrilled to welcome a few of our distributors from all around the world to Stockholm. This intensive meeting was a fantastic opportunity to connect, strengthen our partnerships, and share insights. Thank you to everyone who traveled from near and far for your dedication, enthusiasm, and valuable contributions! Here’s to continued collaboration and success, all in the service of our customers! 🚀 Bio-Connect BV, Koma Biotech, 上海逍鹏生物科技有限公司, Voden Medical Instruments S.p.A., #B2Bio #BioLamina #Collaboration #DistributorMeeting #Biotech #celltherapy #cellandgenetherapy #Biolaminin
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🌟 Save the date for our Innovation Showcase at ISSCR! 🌟 Attending #ISSCR2024 ? Don't miss our exclusive Innovation Showcase, "Biolaminin® technology: supporting standardization for translational success". Our guest speakers, Dr. Terri Gaskell from Rinri Therapeutics and Dr. Brian Hawkins from Pluristyx, Inc. will share their stories of translational success. Dr. Ilse Eidhof, from Karolinska Institutet/ Lund University, will discuss how defined culture conditions robustly maintain human stem cell pluripotency via tightly controlled Ca2+ signaling. Evan L. Graham, PhD from our team will introduce and moderate the session. 📅 Date: July 11 📍 Location: Hall G2, Level 2 ⏰ Time: 18:00 Refreshments will be provided and one lucky attendee will have their name drawn to win a gift card. Pre-register now ➡ https://lnkd.in/dsgtQEX9 We look forward to seeing you there! #BioLamina #InnovationShowcase #StemCellResearch #RegenerativeMedicine #HealthcareInnovation
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Present at The Extracellular Matrix Pharmacology Congress in Copenhagen now? Don't miss Dr. Noah F.'s highlighted poster presentation P107 from 17:00 today! Learn more about full-length laminins and how they are crucial for recreating the cellular niche in vitro. #laminin #ECM2024 #matrixbiology #BioLamina
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Hamburg is calling! We look forward to meeting you at the International Society for Stem Cell Research's Annual meeting in less than a month! Meet our team at booth #903. We would love to learn more about your research and discuss how our full-length Biolaminin® matrices can support your cell culture. Are you attending too? Let us know in the comments below! Poster presentations, innovation showcases, special celebrations... Learn more about what we planned for you ➡ https://lnkd.in/dfgUxXbS #ISSCR2024 #stemcellresearch #stemcelltherapy #regenerativemedicine #BioLamina #Biolaminin
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