Dietary supplementation with glutamate precursor α-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs

L Wang, Y Hou, D Yi, Y Li, B Ding, H Zhu, J Liu, H Xiao…�- Amino acids, 2015 - Springer
There is growing interest in glutamate as a functional amino acid in nutrition and health. This
study was conducted to determine whether glutamate precursor α-ketoglutarate (AKG) could�…

Dietary L-arginine supplementation alleviates liver injury caused by Escherichia coli LPS in weaned pigs

Q Li, Y Liu, Z Che, H Zhu, G Meng, Y Hou…�- Innate�…, 2012 - journals.sagepub.com
This study was conducted to evaluate whether dietary supplementation with l-arginine (Arg)
could attenuate Escherichia coli LPS-induced liver injury through the TLR4 signaling�…

Dietary N-acetylcysteine supplementation alleviates liver injury in lipopolysaccharide-challenged piglets

D Yi, Y Hou, L Wang, B Ding, Z Yang, J Li…�- British Journal of�…, 2014 - cambridge.org
The present study was carried out to determine whether N-acetylcysteine (NAC) could
modulate liver injury in a lipopolysaccharide (LPS)-challenged piglet model. For this�…

Aspartate alleviates liver injury and regulates mRNA expressions of TLR4 and NOD signaling-related genes in weaned pigs after lipopolysaccharide challenge

W Leng, Y Liu, H Shi, S Li, H Zhu, D Pi, Y Hou…�- The Journal of nutritional�…, 2014 - Elsevier
Pro-inflammatory cytokines play a critical role in many models of liver injury. In addition,
aspartate (Asp) plays an important role in many biological and physiological processes�…

Dietary α-ketoglutarate supplementation ameliorates intestinal injury in lipopolysaccharide-challenged piglets

Y Hou, L Wang, B Ding, Y Liu, H Zhu, J Liu, Y Li, X Wu…�- Amino acids, 2010 - Springer
Neonates are at increased risk for inflammatory bowel disease, but effective prevention and
treatments are currently limited. This study was conducted with the lipopolysaccharide (LPS)�…

[HTML][HTML] Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia

VF Cruzat, A Bittencourt, SP Scomazzon, JSM Leite…�- Nutrition, 2014 - Elsevier
Objective The aim of the present study was to determine the effects of oral supplementation
with l-glutamine plus l-alanine (GLN+ ALA), both in the free form and l-alanyl-l-glutamine�…

N-Acetyl-l-Glutamine, A Liquid-Stable Source of Glutamine, Partially Prevents Changes in Body Weight and on Intestinal Immunity Induced by Protein Energy�…

JM L�pez-Pedrosa, M Manzano, JH Baxter…�- Digestive Diseases and�…, 2007 - Springer
The goal of this study was to evaluate the preventive effect of free glutamine versus N-acetyl-
l-glutamine, a liquid-stable source of glutamine, on gut damage induced by protein energy�…

[HTML][HTML] Dietary glutamate supplementation ameliorates mycotoxin-induced abnormalities in the intestinal structure and expression of amino acid transporters in�…

J Duan, J Yin, M Wu, P Liao, D Deng, G Liu, Q Wen…�- PLoS�…, 2014 - journals.plos.org
The purpose of this study was to investigate the hypothesis that dietary supplementation with
glutamic acid has beneficial effects on growth performance, antioxidant system, intestinal�…

Dietary supplementation with l-glutamate and l-aspartate alleviates oxidative stress in weaned piglets challenged with hydrogen peroxide

J Duan, J Yin, W Ren, T Liu, Z Cui, X Huang, L Wu…�- Amino acids, 2016 - Springer
This study was to evaluate the protective roles of l-glutamate (Glu) and l-aspartate (Asp) in
weaned piglets challenged with H 2 O 2. Forty weaned piglets were assigned randomly into�…

l-Glutamate nutrition and metabolism in swine

Y Hou, G Wu�- Amino acids, 2018 - Springer
Abstract l-Glutamate (Glu) has traditionally not been considered as a nutrient needed in
diets for humans and other animals (including swine) due to the unsubstantiated assumption�…