People

Principal investigator

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Who

Research interests, hobbies

DeGrado

William DeGrado, PhD
Professor and Principal Investigator

[email protected]

UCSF profile

De novo protein design; membrane proteins; small molecule drug discovery for antimicrobials, influenza A virus, antifibrotics, and neurodegeneration; chemical biology; peptide design

Cycling, Music, Dance

Senior scientists

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Who

Research interests

Jo

Hyunil Jo, PhD
Assistant Adjunct Professor

[email protected]

Medicinal chemistry to fight against unconquered human diseases; chemical biology to understand the fundamental processes in life

Postdoctoral scholars

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Who

Research interests, hobbies

Hyunjun Yang, PhD
Postdoctoral Scholar

[email protected]

Molecular fingerprinting of prion strains in vivo and in vitro

Golf

Kehan Chen, PhD
Postdoctoral Scholar

[email protected]

De novo design and characterization of membrane proteins, especially transporters and channels

Mineralogy and linguistics

Lee Schnaider, PhD
Postdoctoral Scholar

[email protected]

Design and characterization of de novo proteins for biomedical applications

Redwood and mountain enthusiast. I love hiking, reading and live music.

Lei Lu, PhD
Postdoctoral Scholar

[email protected]

Study protein structures, PTMs and interactions using bioengineering, proteomics and design methods

Basketball, Soccer, Dota2

Ethel Tackie-Yarboi, PhD
Postdoctoral Scholar

[email protected]

Synthesis and functional characterization of AND-gated cancer therapeutics

reading, cooking, and spending time with family

Katie Hatstat
Postdoctoral Scholar

[email protected]

Design and characterization of transmembrane proteins and signaling mechanisms

running, soccer, making up recipes, and adventuring in the mountains with her dog

Yuda Chen
Postdoctoral Scholar

[email protected]

Protein design with chemical biology

Henry Pan
Postdoctoral Scholar

[email protected]

Amyloids, cryo-EM, fluorescence microscopy, and peptide design

Running, sports leagues, playing the piano, and cooking plant-based cuisine

Kaipeng Hou
Postdoctoral Scholar

[email protected]

De novo metalloprotein design

Sophia Tan
Postdoctoral Scholar

[email protected]

Automated de novo design of ligand-binding proteins using structural proteomics
board games, rock climbing

Ian Bakanas
Postdoctoral Scholar

[email protected]

Design and characterization of de novo enzymes to catalyze new-to-nature transformations

Baking bread, watching basketball, and playing tennis poorly

Sagar Bhattacharya
Postdoctoral Scholar

[email protected]

De novo protein design for enzyme catalysis and drug delivery in vivo

Chess

Nam Hyeong Kim
Postdoctoral Scholar

[email protected]

Function-directed protein design for biomedical applications with a parametrized scaffold and protein structure prediction incorporating molecular dynamics
Drumming, watching football, and sitting in the park

Adam McConnell
Postdoctoral Scholar

[email protected]

De novo protein design towards pharmaceutical and biomedical applications
Watching stand-up comedy, drumming, reading scifi/fantasy novels, solving nonograms

Graduate students

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Who

Research interests, hobbies

Rian Kormos
Biophysics (BP) program

[email protected]

Development and validation of improved algorithms for de novo design of small molecule impermeable nanostructures

In my free time, I enjoy long walks around the city, backpacking, teaching myself the piano, and playing Dungeons & Dragons.

Leo Chen
Chemistry and Chemical Biology (CCB) program

[email protected]

Development of protease-activated tumor imaging agents and cancer therapeutics

Rose Yang
Chemistry and Chemical Biology (CCB) program

[email protected]

Design and characterization of de novo peptides for targeting tau polymorphs present in Alzheimer's disease

Outside of the lab, I enjoy reading, cooking, and going on runs through Golden Gate Park.

Stephanie Ouchida
Chemistry and Chemical Biology (CCB) program

[email protected]

Design of de novo small molecule binding proteins for drug delivery

I enjoy rock climbing, playing basketball, going to the gym, playing video games, all things BTS, and drinking boba!

Henry Scott
Biophysics (BP) program

[email protected]

Design and characterization of bioorthogonal intercellular signaling systems.
Outside of lab I enjoy surfing, reading, playing chess, and searching for frog-themed memes.

Angelika Arada
Biophysics (BP) program

[email protected]

Design and characterization of de novo proteins for small molecule binding
Outside of lab, I like going to concerts, trying new restaurants, and playing video games.

Nicholas Freitas
Biophysics (BP) program

[email protected]

Development of Physics-based computational methods for de novo enzyme design.
Camping, hiking, photography, and astronomy

Giovanni Aviles
Biophysics (BP) program

[email protected]

Design and characterization of artificial metalloenzymes

Outside of lab, I enjoy climbing, traveling, and learning languages

Visiting Scholars

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Who

Research interests, hobbies

Seth Fraden
Brandeis University

[email protected]

Supramolecular assemblies

 

Oliwia Lidwin
Rosetta Commons REU from Johns Hopkins University

[email protected]

Small molecule binding for fluorescence

 

Learning languages, hiking, listening to music, reading

Associated adjunct faculty

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Who

Research interests

Yibing Wu, PhD
Assistant Adjunct Professor

[email protected]

Structure and dynamics of proteins using multidimensional NMR spectroscopy
protein modelling and drug docking
deep learning-based protein design and drug discovery

Administrative staffs

PHOTO

WHO

What I do, hobbies

 

Marcus Cavness, PhD
Administrative Assistant

[email protected]

Support administrative, organizational, and scheduling needs for the lab