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Data from boreal, temperate and tropical forests over the past three decades reveal that the global forest carbon sink has remained steady during that time, despite considerable regional variation.
Enhancer-driven genomic recording of transcriptional activity in multiplex (ENGRAM) is used for multiplex recording of the cell-type-specific activities of dozens to hundreds of cis-regulatory elements with high fidelity, sensitivity and reproducibility.
Precision measurement of the dynamical magnetoelectric coupling in an exfoliated van der Waals multiferroic shows a giant natural optical activity at terahertz frequencies.
The application of pressure effectively suppresses the spin–charge order in trilayer nickelate La4Ni3O10−δ single crystals, leading to the emergence of superconductivity.
IL-11 is identified as a key regulator of ERK–AMPK–mTORC1 signalling, metabolism, inflammation and age-related disease and lifespan in mouse and human.
Embedding of a new engineered thermostable hydrolase into polymer materials enables the production of biodegradable and home-compostable plastics suitable for industrial packaging applications.
An analysis of the impact of logging intensity on biodiversity in tropical forests in Sabah, Malaysia, identifies a threshold of tree biomass removal below which logged forests still have conservation value.
Changes in day length, conveyed by the preoptic area, drive axonal neurotransmitter reorganization in median raphe dual serotonin–glutamate neurons to regulate behaviour and sleep timing, highlighting a photoperiod-sensitive brain circuit.
The spectroscopic and photometric observations of a high-mass, transiting warm Jupiter, TIC 241249530 b, with an orbital eccentricity of 0.94, provide evidence that hot Jupiters may have formed by means of a high-eccentricity tidal-migration pathway.
Healthy adults were tracked before, during and after high doses of psilocybin and methylphenidate to assess how psychedelics can change human brain networks, and psilocybin was found to massively disrupt functional connectivity in cortex and subcortex with some changes persisting for weeks.
A study reports the structure and molecular mechanism of the Bil anti-phage defence system, demonstrating that it is the closest prokaryotic homologue of canonical eukaryotic ubiquitination pathways.
A framework that integrates materials, process design, techno-economics and life-cycle assessment can be used to accelerate the development of carbon-capture technology as we aim for a net-zero world.
A high-throughput yeast-based assay is used to identify more than 1,500 activation domains (ADs) in Arabidopsis transcription factors, and a deep learning approach applied to this dataset can predict AD activity on the basis of sequence features.
Mapping of groundwater-dependent ecosystems, which support biodiversity and rural livelihoods, shows they occur on more than one-third of global drylands analysed, but lack protections to safeguard these critical ecosystems and the societies dependent upon them from groundwater depletion.
A stiff hydrogel gel is presented that encapsulates and stabilizes proteins without additives or excipients and uses mechanical strain to release them, offering low-cost and versatile delivery of therapies.
Studies in mice show that telomerase reverse transcriptase (TERT) has a role in enhancing stem cell competition that is independent of its reverse transcriptase activity, and promotes chromatin accessibility and activity of the MYC oncogene.