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Long-term lymphocyte subset number reconstitution is unique but comparable between umbilical cord blood and unrelated bone marrow transplantation
The number of umbilical cord blood transplantation (U-CBT) procedures has been growing annually, but little research has been done on long-term...
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Immune reconstitution, vaccine responses, and rituximab use after ex-vivo CD34-selected myeloablative allogenic hematopoietic cell transplantation
Myeloablative T cell depleted (CD34-selected) hematopoietic cell transplantation (HCT) is associated with less acute and chronic graft versus host...
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Early T-cell reconstitution predicts risk of EBV reactivation after allogeneic hematopoietic stem cell transplantation
The quality of immune reconstitution (IR) is crucial for the outcome of patients who received allogeneic hematopoietic stem cell transplantation...
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Lymphocyte subset analysis to evaluate the prognosis of HIV-negative patients with pneumocystis pneumonia
ObjectivesWe analysed the peripheral blood lymphocyte subsets of human immunodeficiency virus (HIV)-negative patients infected with pneumocystis...
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Immune reconstitution and survival of patients with parvovirus B19 related pure red cell aplasia after haplo-PBSCT
Parvovirus B19 (PvB19) infection and PvB19 related pure red cell aplasia (PRCA) in recipients with allogeneic hematopoietic stem cell transplantation...
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The Place of Immune Reconstitution Therapy in the Management of Relapsing Multiple Sclerosis in France: An Expert Consensus
The treatment strategy in relapsing multiple sclerosis (RMS) is a complex decision requiring individualization of treatment sequences to maximize...
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Infectious complications, immune reconstitution, and infection prophylaxis after CD19 chimeric antigen receptor T-cell therapy
CD19-targeted chimeric antigen receptor (CAR) T-cell becomes a breakthrough therapy providing excellent remission rates and durable disease control...
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Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation
Omidubicel (nicotinamide-expanded cord blood) is a potential alternative source for allogeneic hematopoietic cell transplantation (HCT) when an...
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Impact of Natural Killer (NK) Cells on Immune Reconstitution, and Their Potential as a Biomarker of Disease Activity, in Alemtuzumab-Treated Patients with Relapsing Remitting Multiple Sclerosis: An Observational Study
BackgroundDefining immune mechanisms leading to multiple sclerosis (MS) is difficult, due to the great inter-individual difference in immune system...
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Combining blinatumomab and donor lymphocyte infusion in B-ALL patients relapsing after allogeneic hematopoietic cell transplantation: a study of the SFGM-TC
Relapsed B-cell acute lymphoblastic leukemia (B-ALL) after allogeneic stem cell transplantation (allo-HCT) still represents a major concern with poor...
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CTLA4Ig-primed donor lymphocyte infusions following haploidentical transplantation improve outcome with a distinct pattern of early immune reconstitution as compared to conventional donor lymphocyte infusions in advanced hematological malignancies
CTLA4Ig has a unique property to spare or even potentiate natural killer (NK) cell-mediated cytotoxicity, whilst inhibiting T cell activation. We...
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B cells in multiple sclerosis — from targeted depletion to immune reconstitution therapies
Increasing evidence indicates the involvement of B cells in the pathogenesis of multiple sclerosis (MS), but their precise roles are unclear. In this...
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Low class–switched memory B cells predict the need for continued immunoglobulin replacement following B cell reconstitution after rituximab: a case series and review of the literature
BackgroundRituximab is a chimeric monoclonal antibody that is used in a wide variety of conditions, ranging from non-Hodgkin lymphoma to autoimmune...
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Patients with systemic sclerosis and low CD4 numbers after autologous stem cell transplantation have a favorable outcome
BackgroundTreatment with high-dose chemotherapy followed by autologous hematopoietic stem cell transplantation (aHSCT) is an intensive treatment...
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Expert Narrative Review of the Safety of Cladribine Tablets for the Management of Relapsing Multiple Sclerosis
Cladribine tablets (CladT) is a highly active oral disease-modifying therapy (DMT) for the management of relapsing multiple sclerosis (RMS). CladT...
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Long-term survival and polyclonal immunoglobulin reconstitution after allogeneic stem cell transplantation in multiple myeloma
Despite significant progress made in the treatment of patients with multiple myeloma (MM) in the last decade, for patients with early relapse or...
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Tofacitinib for new-onset adult patients with anti-melanoma differentiation-associated 5 gene antibody positive dermatomyositis
ObjectiveWe aimed to investigate the efficacy and safety of tofacitinib in adult anti-melanoma differentiation-associated 5 gene (Anti-MDA5)...
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Chromosome 22q11.2 Deletion (DiGeorge Syndrome): Immunologic Features, Diagnosis, and Management
Purpose of ReviewThis review focuses on immunologic findings, relationships among immunologic findings and associated conditions of autoimmunity and...
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Early B cells repopulation in multiple sclerosis patients treated with rituximab is not predictive of a risk of relapse or clinical progression
BackgroundIt is currently unknown whether early B cell reconstitution (EBR) in MS patients under rituximab is associated with a risk of relapse or...
