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Concordance study on Y-STRs typing between SeqStudio™ genetic analyzer for HID and MiSeq™ FGx forensic genomics system
BackgroundMassively Parallel Sequencing (MPS) allowed an increased number of information to be retrieved from short tandem repeat (STR) analysis,...
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Genetic diversity and forensic application of Y-filer STRs in four major ethnic groups of Pakistan
17 Y-chromosomal STRs which are part of the Yfiler Amplification Kit were investigated in 493 unrelated Pakistani individuals belonging to the...
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Characterization of 58 STRs and 94 SNPs with the ForenSeq™ DNA signature prep kit in Mexican-Mestizos from the Monterrey city (Northeast, Mexico)
BackgroundSTR allele frequency databases from populations are necessary to take full advantage of the increased power of discrimination offered by...
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Exploration of allelic variants in short tandem repeats (STRs) flanking milk production QTLs and their association with milk production traits in Indian water buffaloes
Short tandem repeats (STRs) are co-dominant, highly polymorphic marker loci, distributed throughout the genome and useful for identification and...
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Advanced Emerging Techniques for Forensic DNA Analysis: STRs, SNPs, and mtDNA Analysis
In the year 2022, the prestigious Nobel prize in Physiology or Medicine was given to Svante Pääbo for studying our extinct ancestors’ DNA. Svante...
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Genetic analysis based on 15 autosomal short tandem repeats (STRs) in the Chaouia population, western center Morocco, and genetic relationships with worldwide populations
The complex demographic history of human populations in North Africa has resulted in a high degree of genetic heterogeneity across the region....
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Population genetic analyses of Eastern Chinese Han nationality using ForenSeq™ DNA Signature Prep Kit
Currently, the most commonly used method for human identification and kinship analysis in forensic genetics is the detection of length polymorphism...
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Analysis of 26 STR loci (PowerPlex® Fusion 6C System) in a mestizo population from Mexico city
BackgroundShort tandem repeats (STRs) are the most widely used genetic markers in forensic genetics. Therefore, it is essential to document genetic...
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X-STRs: Potentials and Applications
The chapter describes potential and utility of X-STRs in forensic DNA analysis. The presently available X-STR multiplex systems, details of known...
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Forensic efficiency and genetic polymorphisms of 12 X-chromosomal STR loci in Northeastern Thai populations
Northeastern Thailand comprises one-third of the country and is home to various populations, with Lao Isan constituting the majority, while others...
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Comparative analysis of microsatellites in coding regions provides insights into the adaptability of the giant panda, polar bear and brown bear
Short Tandem repeats (STRs) often occur within coding regions and adaptive selection could play a vital role in shaping the landscape of coding STRs....
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Global abundance of short tandem repeats is non-random in rodents and primates
BackgroundWhile of predominant abundance across vertebrate genomes and significant biological implications, the relevance of short tandem repeats...
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LUSTR: a new customizable tool for calling genome-wide germline and somatic short tandem repeat variants
BackgroundShort tandem repeats (STRs) are widely distributed across the human genome and are associated with numerous neurological disorders....
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Spatial mapping of the total transcriptome by in situ polyadenylation
Spatial transcriptomics reveals the spatial context of gene expression, but current methods are limited to assaying polyadenylated (A-tailed) RNA...
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STRling: a k-mer counting approach that detects short tandem repeat expansions at known and novel loci
Expansions of short tandem repeats (STRs) cause many rare diseases. Expansion detection is challenging with short-read DNA sequencing data since...
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Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains
Despite unequivocal roles in disease, transcription factors (TFs) remain largely untapped as pharmacologic targets due to the challenges in targeting...
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Unraveling the paternal genetic structure and forensic traits of the Hui population in Liaoning Province, China using Y-chromosome analysis
The Hui people are the second-largest ethnic minority in China, and they are distributed throughout the country. A previous study explored the...
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Geographical structuring and low diversity of paternal lineages in Bahrain shown by analysis of 27 Y-STRs
We have determined the distribution of Y-chromosomal haplotypes and predicted haplogroups in the ethnically diverse Kingdom of Bahrain, a small...
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Short Tandem Repeat Mutations in Paternity Analysis
Polymorphic autosomal short tandem repeats (STRs) are a class of genetic markers that are routinely being used for parentage testing purposes in...
