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1. Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-κB signaling

   Inflammatory cytokines-induced activation of the nuclear factor κB (NF-κB) pathway plays a critical role in the pathogenesis of osteoarthritis (OA)....

   Su’an Tang, Xiaoyu Nie, ... Changhai Ding in Cell Death & Disease

   Article Open access 09 August 2022
   

2. Biology and therapeutic potential of mesenchymal stem cell extracellular vesicles in axial spondyloarthritis

   Axial spondyloarthritis (AxSpA) is a chronic, inflammatory, autoimmune disease that predominantly affects the joints of the spine, causes chronic...

   Fataneh Tavasolian, Robert D. Inman in Communications Biology

   Article Open access 14 April 2023
   

3. DeepVelo: deep learning extends RNA velocity to multi-lineage systems with cell-specific kinetics

   Existing RNA velocity estimation methods strongly rely on predefined dynamics and cell-agnostic constant transcriptional kinetic rates, assumptions...

   Haotian Cui, Hassaan Maan, ... Bo Wang in Genome Biology

   Article Open access 19 January 2024
   

4. Future of low back pain: unravelling IVD components and MSCs’ potential

   Low back pain (LBP) mainly emerges from intervertebral disc (IVD) degeneration. However, the failing mechanism of IVD ́s components, like the annulus...

   Raquel Leão Monteiro in Cell Regeneration

   Article Open access 16 January 2024
   

5. Effect of miR-21 in mesenchymal stem cells-derived extracellular vesicles behavior

   Background

   A challenging new branch of research related to aging-associated diseases is the identification of miRNAs capable of modulating the...

   Miriam Morente-López, Rocio Mato-Basalo, ... María C. Arufe in Stem Cell Research & Therapy

   Article Open access 21 December 2023
   

6. Multipotent Embryonic Lung Progenitors: Foundational Units of In Vitro and In Vivo Lung Organogenesis

   Transient, tissue-specific, embryonic progenitors are important cell populations in vertebrate development. In the course of respiratory system...

   Laertis Ikonomou, Maria Yampolskaya, Pankaj Mehta in Engineering Translational Models of Lung Homeostasis and Disease

   Chapter Open access 2023
   

7. Comparison of genome-wide DNA methylation patterns between antler precartilage and cartilage

   Deer antlers are the only mammalian organs that can fully regenerate after being lost and provide a valuable model for cartilage development. As one...

   Jin Wu, Fan Yang, ... Dong Zheng in Molecular Genetics and Genomics

   Article 14 December 2022
   

8. Efficacy of IFN-γ-Primed Umbilical Cord-Derived Mesenchymal Stem Cells on Temporomandibular Joint Osteoarthritis

   Background:

   Temporomandibular joint osteoarthritis (TMJOA) is a degenerative disease affecting the cartilage and subchondral bone, leading to...

   Hyunjeong Kim, Yerin Kim, ... Bu-Kyu Lee in Tissue Engineering and Regenerative Medicine

   Article 08 January 2024
   

9. Viral Gene Delivery in Chondrocytes

   Viral gene transfer, known as transduction, is a powerful research tool for studying the biology of chondrocytes in novel ways and also a technology...

   Christopher V. Nagelli, Christopher H. Evans, Rodolfo E. De La Vega in Cartilage Tissue Engineering

   Protocol 2023
   

10. Therapy free of cells vs human mesenchymal stem cells from umbilical cord stroma to treat the inflammation in OA

    Osteoarthritis (OA) is closely linked to the increase in the number of senescent cells in joint tissues, and the senescence-associated secretory...

    Miriam Morente-López, Rocío Mato-Basalo, ... María C. Arufe in Cellular and Molecular Life Sciences

    Article Open access 20 October 2022
    

11. Managing Temporomandibular Joint Osteoarthritis by Dental Stem Cell Secretome

    The potential therapeutic role of the Dental Pulp Stem Cells Secretome (SECR) in a rat model of experimentally induced Temporomandibular Joint (TMJ)...

    Maria Bousnaki, Athina Bakopoulou, ... Petros Koidis in Stem Cell Reviews and Reports

    Article Open access 26 September 2023
    

12. 1α,25-Dihydroxyvitamin D₃ Regulates microRNA Packaging in Extracellular Matrix Vesicles and Their Release in the Matrix

    Growth plate chondrocytes are regulated by numerous factors and hormones as they mature during endochondral bone formation, including transforming...

    Niels C. Asmussen, Sheikh Alam, ... Barbara D. Boyan in Calcified Tissue International

    Article 25 February 2023
    

13. Expansion and characterization of cells from surgically removed intervertebral disc fragments in xenogen-free medium

    Low back pain due to degeneration of intervertebral disc (IVD) is a major health problem resulting in significant disability as well as adding to the...

    Simran Mujawar, Kruttika Iyengar, ... Rita Mulherkar in Journal of Biosciences

    Article 09 September 2020
    

14. Cells for Cartilage Regeneration

    Cartilage, at all sites of our body, has limited intrinsic capacity to repair. There are numerous methods to use when repairing cartilage, and the...

    Gerjo J. V. M. van Osch, Andrea Barbero, ... Sylvia Nuernberger in Cell Engineering and Regeneration

    Reference work entry 2020
    

15. Short-term response of primary human meniscus cells to simulated microgravity

    Background

    Mechanical unloading of the knee articular cartilage results in cartilage matrix atrophy, signifying the osteoarthritic-inductive potential...

    Zhiyao Ma, David Xinzheyang Li, ... Adetola B. Adesida in Cell Communication and Signaling

    Article Open access 21 June 2024
    

16. A novel mechanism for macrophage pyroptosis in rheumatoid arthritis induced by Pol β deficiency

    Rheumatoid arthritis (RA) is a chronic and inflammatory autoimmune disease. Macrophage pyroptosis, a proinflammatory form of cell death, is...

    Lili Gu, Yuling Sun, ... Zhigang Guo in Cell Death & Disease

    Article Open access 06 July 2022
    

17. Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in a rat intervertebral disc degeneration model

    Intervertebral disc (IVD) degeneration is an asymptomatic pathophysiological condition and a strong causative factor of low back pain. There is no...

    Sobia Ekram, Shumaila Khalid, ... Irfan Khan in Molecular and Cellular Biochemistry

    Article 17 April 2021
    

18. “Bone-SASP” in Skeletal Aging

    Senescence is a complex cell state characterized by stable cell cycle arrest and a unique secretory pattern known as the senescence-associated...

    Ching-Lien Fang, Bin Liu, Mei Wan in Calcified Tissue International

    Article Open access 31 May 2023
    

19. Stem Cell-Based Regeneration of Salivary Glands: From Bench to Clinics

    Exocrine gland regeneration, particularly salivary gland regeneration, remains an exciting arena for the scientific world due to its crucial role in...

    Akshaya Upadhyay, Uyen Cao, ... Simon D. Tran in Handbook of Stem Cell Applications

    Living reference work entry 2023
    

20. Other Non-α1,3Gal Antigens

    Since understanding of the impact in xenoantigenic determinant Galα1,3Gal-R and anti-α1,3Gal Abs during xenoantigenic damages and injuries, other...

    Cheorl-Ho Kim in Glycoimmunology in Xenotransplantation

    Chapter 2024