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Rice Carbohydrate-Binding Malectin-Like Protein, OsCBM1, Contributes to Drought-Stress Tolerance by Participating in NADPH Oxidase-Mediated ROS Production
Carbohydrate-binding malectin/malectin-like domain-containing proteins (CBMs) are a recently identified protein subfamily of lectins that...
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The plant NADPH oxidase RBOHD is required for microbiota homeostasis in leaves
The plant microbiota consists of a multitude of microorganisms that can affect plant health and fitness. However, it is currently unclear how the...
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NADPH Oxidases Revisited: From Function to Structure
This book provides a unique, comprehensive, and up-to-date overview of the various NADPH oxidases and narrates the history of their discovery,...
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NADPH Oxidase System Mediates Cholesterol Secoaldehyde-Induced Oxidative Stress and Cytotoxicity in H9c2 Cardiomyocytes
An oxidized cholesterol species, 3β-hydroxy-5-oxo-5,6-secocholestan-6-al (cholesterol secoaldehyde, ChSeco, or atheronal-A), likely to be formed in...
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Methods to Measure Reactive Oxygen Species Production by NADPH Oxidases
NADPH oxidases (Noxes) are a family of enzymes that catalyze the oxidation of NADPH by molecular oxygen to produce superoxide radical anion (O2•–)...
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Quo Vadis NADPH Oxidases: Perspectives on Clinical Translation
Since the discovery of several new homologs of the NADPH oxidases (NOXs) just over two decades ago, significant progress has been made in our...
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The Phagocyte Oxidase: The Early Years
This autobiographical dialogue describes the scientific interchanges during the 1970s of the Boston-based investigators studying the respiratory...
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Nanoceria potently reduce superoxide fluxes from mitochondrial electron transport chain and plasma membrane NADPH oxidase in human macrophages
Cerium oxide nanoparticles, also known as nanoceria, possess antioxidative and anti-inflammatory activities in animal models of inflammatory...
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Lipid Peroxidation Induced by Reactive Oxygen Species via NADPH-Dependent Oxidative Burst Triggers the Occurrence of Internal Browning in Radish Root
The occurrence of internal browning in radish root is closely related to lipid peroxidation caused by excessive ROS production via NADPH-dependent...
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NADPH containing superoxide-producing thermostable complex from raspberry, apricot, grape, and grape seeds: isolation, purification, and properties
BackgroundNADPH oxidase (Nox) plays a crucial role in reactive oxygen spices (ROS) production and mediates different diseases’ development. Under...
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Reactive oxygen species derived from NADPH oxidase regulate astaxanthin and total fatty acid accumulation in Chromochloris zofingiensis
Many abiotic stresses can promote astaxanthin and total fatty acid (TFA) accumulation in microalgae, but their signal molecules remain undetermined....
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G protein-coupled receptor kinase 2 modifies the cellular reaction to cisplatin through interactions with NADPH oxidase 4
G protein-coupled receptor kinases (GRKs), in addition to their role in modulating signal transduction mechanisms associated with activated G...
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Acclimation of intertidal macroalgae Ulva prolifera to UVB radiation: the important role of alternative oxidase
BackgroundSolar radiation is primarily composed of ultraviolet radiation (UVR, 200 �� 400 nm) and photosynthetically active radiation (PAR, 400 − 700...
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Mining and functional characterization of NADPH-cytochrome P450 reductases of the DNJ biosynthetic pathway in mulberry leaves
Background1-Deoxynojirimycin (DNJ), the main active ingredient in mulberry leaves, with wide applications in the medicine and food industries due to...
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NADPH Oxidase Modulates Ca2+-Dependent Formation of Neutrophil Extracellular Traps
Abstract—Chronic granulomatous disease (CGD) is a severe hereditary immunodeficiency associated with recurrent bacterial and fungal infections as...
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Effect of atorvastatin on AGEs-induced injury of cerebral cortex via inhibiting NADPH oxidase -NF-κB pathway in ApoE−/− mice
Advanced glycation end products (AGEs) are a group of modified proteins and/or lipids with damaging potential. AGEs-RAGE pathway plays a critical...
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SkQ1 Improves Immune Status and Normalizes Activity of NADPH-Generating and Antioxidant Enzymes in Rats with Adjuvant-Induced Rheumatoid Arthritis
AbstractRheumatoid arthritis (RA) is a severe systemic autoimmune inflammatory disease. Oxidative stress and excessive formation of reactive oxygen...
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ELABELA attenuates deoxycorticosterone acetate/salt-induced hypertension and renal injury by inhibition of NADPH oxidase/ROS/NLRP3 inflammasome pathway
ELABELA (ELA), a 32-residue hormone peptide abundantly expressed in adult kidneys, has been identified as a novel endogenous ligand for APJ/Apelin...
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Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice
Brain aging proceeds with cellular and molecular changes in the limbic system. Aging-dependent changes might affect emotion and stress coping, yet...
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NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and death worldwide. Peroxynitrite, formed from nitric oxide, which is...
