Search
Search Results
-
Quantitative Measurement of Tau Aggregation in Genetically Modified Rats with Neurodegeneration
Animal models of neurodegenerative diseases have helped us to better understand the pathogenesis of neurodegenerative diseases. However, recent...
-
5-HT Neural System Abnormalities in PTSD Model Rats
To do translational research on illness, a suitable animal model is needed. Since the symptoms of post-traumatic stress disorder (PTSD) exist across...
-
Cognitive Enhancement Through Vagus Nerve Stimulation: Methodological Considerations for Behavioral Studies in Rats
Optimal cognition is maintained by a balance of excitatory and inhibitory signaling in brain regions such as the prefrontal cortex and hippocampus....
-
Neonatal olfactory bulbectomy causes dendritic spine retraction in dorsal hippocampal CA3 neurons in female rats and spatial learning deficits in male rats
Olfactory bulbectomy (OBX) is an experimental strategy that is widely employed because it produces changes at different levels (from behavioral to...
-
Copulation in Rats: Analysis of Behavioral and Seminal Parameters
Male copulation in mammals consists of motor and genital components. Two distinct and complementary aspects of copulation are reviewed: masculine...
-
Electrophysiological Techniques for Studying Tactile Perception in Rats
Neurons communicate by electrical and chemical signals. Neurophysiological studies measuring and manipulating these signals are therefore of utmost...
-
Spinal cord injury leads to more neurodegeneration in the hippocampus of aged male rats compared to young rats
Although the disruptive effects of spinal cord injury (SCI) on the hippocampus have been confirmed in some animal studies, no study has investigated...
-
Comparative pharmacokinetic investigation on crocetin in hyperlipidemia and normal rats after oral administration
Crocetin as one of the main components of saffron possesses a lot of pharmacological effects, especially the beneficial effects in the treatment of...
-
Mapping the neuroanatomical abnormalities in a phenotype of male compulsive rats
Compulsivity is considered a transdiagnostic dimension in obsessive–compulsive and related disorders, characterized by heterogeneous cognitive and...
-
Effects of linalool on postoperative peritoneal adhesions in rats
The current study examines the effects of linalool in preventing postoperative abdominal adhesions. Twenty male Wistar rats were randomly divided...
-
SESN2 attenuates sevoflurane-induced cognitive impairment and neuroinflammation in rats
Long-term use of sevoflurane, an inhalation anesthetic, could negatively impact cognitive function. Current studies have suggested that cognitive...
-
Characterization of Gut Microbiota in Rats and Rhesus Monkeys After Methamphetamine Self-administration
Methamphetamine (MA) is one of the most abused drugs globally, but the mechanism of its addiction remains unclear. Several animal studies have shown...
-
Hesperidin neuroprotective effects against carbon monoxide-induced toxicity in male rats
Carbon monoxide (CO) is produced via incomplete combustion of fossil fuels and it may cause long-term neurological sequel upon exposure. Hesperidin...
-
Nanoselenium attenuates renal ischemia-reperfusion injury in rats
Using selenium (Se) nanoparticles has received attention in recent years because of their therapeutic benefits due to their anticancer, antioxidant,...
-
Spontaneous Regeneration after Hypoglossal Nerve Injury with Long Nerve Resection in Rats
Spontaneous neural regeneration may occur in peripheral nerve injury after nerve resection with a relatively short gap, whereas regeneration does not...
-
Endothelin mediates sex-differences in acclimation to high salt diet in rats
IntroductionCurrent understanding of sodium (Na + ) handling is based on studies done primarily in males. Contrary to the gradual increase in high...
-
Aromatase inhibition and ketamine in rats: sex-differences in antidepressant-like efficacy
BackgroundKetamine has been recently approved to treat resistant depression; however preclinical studies showed sex differences in its efficacy. Sex...
-
Neurexin1α knockout in rats causes aberrant social behaviour: relevance for autism and schizophrenia
RationaleGenetic and environmental factors cause neuropsychiatric disorders through complex interactions that are far from understood....
-
Microalbuminuria in Rats Treated with D-Nitroarginine Methyl Ether
Microalbuminuria is an early symptom and prognostic marker of the progression of renal pathology. The analysis of the role of anionic components of...
-
Divergent Pattern of Development in Rats and Humans
Rattus norvegicus is the second most used laboratory species and the most widely used model in neuroscience. Nonetheless, there is still no agreement...
