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Missing pieces of the pituitary puzzle: participation of extra-adenohypophyseal placode-lineage cells in the adult pituitary gland
The pituitary gland is a major endocrine tissue composing of two distinct entities, the adenohypophysis (anterior pituitary, cranial placode origin)...
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MRI atlas of the pituitary gland in young female adults
The probabilistic topography and inter-individual variability of the pituitary gland (PG) remain undetermined. The absence of a standardized...
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Benign and Malignant Tumors of the Pituitary Gland
Pituitary glandPituitary gland tumors represent approximately 10–15% of all brain tumorsBrain tumor and the most common neoplasmsNeoplasm of the... -
Structure–function relationship of the pituitary gland in anorexia nervosa and intense physical activity
Patients with Anorexia Nervosa (AN) and athletes share intense physical activity and pituitary hormonal disturbances related to absolute (AN) or...
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Knockout mice with pituitary malformations help identify human cases of hypopituitarism
BackgroundCongenital hypopituitarism (CH) and its associated syndromes, septo-optic dysplasia (SOD) and holoprosencephaly (HPE), are midline defects...
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Identification and gene expression profiling of human gonadotrophic pituitary adenoma stem cells
BackgroundGonadotrophic pituitary adenoma is a major subtype of pituitary adenoma in the sellar region, but it is rarely involved in the...
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Suspected olfactory meningioma and synchronous pituitary microadenoma in a canine patient treated with radiation therapy
The authors report on the rare occurrence of dual synchronous primary brain tumors in a canine patient, successful treatment with radiation therapy,...
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Single-cell transcriptomic analysis reveals tumor cell heterogeneity and immune microenvironment features of pituitary neuroendocrine tumors
BackgroundPituitary neuroendocrine tumors (PitNETs) are one of the most common types of intracranial tumors. Currently, the cellular characteristics...
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Radiomics of pituitary adenoma using computer vision: a review
AbstractPituitary adenomas (PA) represent the most common type of sellar neoplasm. Extracting relevant information from radiological images is...
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The potential link between acromegaly and risk of acute ischemic stroke in patients with pituitary adenoma: a new perspective
Acromegaly is an endocrine disorder due to the excess production of growth hormone (GH) from the anterior pituitary gland after closed epiphyseal...
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A Review of Brain and Pituitary Gland MRI Findings in Patients with Ataxia and Hypogonadism
The association of cerebellar ataxia and hypogonadism occurs in a heterogeneous group of disorders, caused by different genetic mutations often...
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Changes in Secretion of the Thyroid and Pituitary Glands with a Gradual Decrease in Deuterium Body Content
We studied changes in the secretion of thyroid hormones and pituitary thyroid-stimulating hormone (TSH) in young mature male Wistar rats during...
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Resistance exercise stress: theoretical mechanisms for growth hormone processing and release from the anterior pituitary somatotroph
Heavy resistance exercise (HRE) is the most effective method for inducing muscular hypertrophy and stimulating anabolic hormones, including growth...
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Brain Control over Pituitary Gland Hormones
Endocrine organs release their products, hormones, into peripheral blood to travel great distances to exert their biological effects. The brain is... -
Postnatal developmental trajectory of sex-biased gene expression in the mouse pituitary gland
BackgroundThe pituitary gland regulates essential physiological processes such as growth, pubertal onset, stress response, metabolism, reproduction,...
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Iatrogenic Alzheimer’s disease in recipients of cadaveric pituitary-derived growth hormone
Alzheimer’s disease (AD) is characterized pathologically by amyloid-beta (Aβ) deposition in brain parenchyma and blood vessels (as cerebral amyloid...
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Regulation of the Hypothalamo-Pituitary-Adrenal Axis in Pregnancy and Lactation
Physiological and behavioural responses to stress are critical to ensure individual survival in all species. This is even more important when the... -
Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors
Human growth hormone (GH) is the indispensable hormone for the maintenance of normal physiological functions of the human body, including the growth,...
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Individual Features of the Hypothalamic—Pituitary—Thyroid Axis Functioning during Aging in Non-Human Primates
Individual features of age-related changes in the function of the neuroendocrine systems are an important problem as the basic component of a...