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Protective effect of alpha‑lipoic acid against in utero cytarabine exposure-induced hepatotoxicity in rat female neonates
Cytarabine, an anti-metabolite drug, remains the mainstay of treatment for hematological malignancies. It causes various toxic effects including...
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Sex Dimorphism in Pain Threshold and Neuroinflammatory Response: The Protective Effect of Female Sexual Hormones on Behavior and Seizures in an Allergic Rhinitis Model
Our previous research demonstrated that allergic rhinitis could impact behavior and seizure threshold in male mice. However, due to the complex...
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Protective effects of cardamom aqueous extract against tamoxifen-induced pancreatic injury in female rats
Tamoxifen (TAM) is a commonly used drug for breast cancer treatment. Although effective, TAM has deleterious effects on many organs. The toxic...
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Role of antioxidative activity in the docosahexaenoic acid’s enteroprotective effect in the indomethacin-induced small intestinal injury model
Therapeutic effect of non-steroidal anti-inflammatory drugs (NSAIDs) has been related with gastrointestinal injury. Docosahexaenoic acid (DHA), an...
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Investigation of cardioprotective effect of lercanidipine on doxorubicin-induced cardiotoxicity
Although doxorubicin (DOX) is an effective anti-neoplastic drug for many types of cancer, particularly dose-related cardiotoxicity limits the use of...
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The effect of education on safe use of pesticides based on the health belief model
ObjectiveIn agricultural activities, pesticide use is critical, but poisoning issues are one of the most important occupational hazards for farmers....
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Promising effect of Geranium robertianum L. leaves and Aloe vera gel powder on Aspirin®-induced gastric ulcers in Wistar rats: anxiolytic behavioural effect, antioxidant activity, and protective pathways
BackgroundMany drugs have been restricted in the treatment of gastric ulcers (GU). So, herbal medicines are now in great demand for their better...
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Uninterrupted prolonged sitting and arterial stiffness: moderating effect of prior aerobic exercise in physically active adults
PurposeProlonged sitting acutely increases arterial stiffness, with interruption strategies only providing limited success in offsetting these rises....
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The effect of physical barriers under a raised house on mosquito entry: an experimental study in rural Gambia
BackgroundAnopheles gambiae , the major malaria mosquito in sub-Saharan Africa, feed largely indoors at night. Raising a house off the ground with no...
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Schizophrenia and Its Effect on Marital Satisfaction
Schizophrenia is a chronic psychological disorder; its diagnosis can be described as life changing for some individuals. Schizophrenia has a profound...
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Protective role of mirtazapine in adult female Mecp2+/− mice and patients with Rett syndrome
BackgroundRett syndrome (RTT), an X-linked neurodevelopmental rare disease mainly caused by MECP2 -gene mutations, is a prototypic intellectual...
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The Effect of Psychological Resilience and Coping Strategies on Mental Health of Nurses
Introduction: Nursing professional is considered to be stressful with impact on nurses’ mental health. Aim: The aim of this study was to investigate...
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Evaluation of the protective effect of losartan in acetaminophen-induced liver and kidney damage in mice
Acetaminophen is widely used among humans as an antipyretic and analgesic. In this study, the protective effect of losartan in hepatotoxicity and...
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Exploring the Combined Effect of Exercise and Apigenin on Aluminium-Induced Neurotoxicity in Zebrafish
Aluminium (AL) is a strong environmental neurotoxin linked to neurodegenerative disorders. Widespread industrial use leads to its presence in water...
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Effect of elevated temperature and hydrocortisone addition on the proliferation of fibroblasts
Hyperthermia along with hydrocortisone (HC) are proven teratogens that can negatively influence embryo development during early pregnancy....
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Prmt7 regulates the JAK/STAT/Socs3 signaling pathway in postmenopausal cardiomyopathy
Protein arginine methyltransferases (PRMTs) modulate diverse cellular processes, including stress responses. The present study explored the role of...
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Cardioprotective effect of oleuropein in a cisplatin-induced cardiotoxicity model in rats
This study investigated the cardioprotective effect of oleuropein against cisplatin-induced cardiac damage in terms of inflammatory, oxidative stress...
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Lactoferrin Has a Protective Effect on Mouse Brain Cells after Acute Gamma Irradiation of the Head
We studied the effect of human lactoferrin on cells of the hippocampal dentate gyrus of 2-2.5-month-old male C57BL/6 mice after acute gamma...
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Effect of renin angiotensin blockers on angiotensin converting enzyme 2 level in cardiovascular patients
BackgroundRenin–angiotensin–aldosterone system (RAAS) is hypothesized to be in the center of COVID pathophysiology as the angiotensin converting...
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Head Impact Kinematics and Brain Tissue Strains in High School Lacrosse
Male lacrosse and female lacrosse have differences in history, rules, and equipment. There is current debate regarding the need for enhanced...
