Abstract
Endometrial carcinoma is one of the most commonly occurring gynecological malignancies. It is diagnosed mostly at the age of 50, yet 5% of cases belong to females of reproductive age. Owing to its wide classification on various parameters such as histology, microscopic features, pathogenesis, and prognosis, there is no well-established method to screen endometrial carcinoma at present. However, NGS and microarray-based tools alone or in combination with traditional techniques corresponding to morphological tumor identification could provide early and precise diagnosis. An amalgamation of genetic counseling with clinical and prognostic assessment could possibly serve to improve the diagnosis of endometrial carcinoma. This chapter sheds light on the etiology of endometrial carcinoma and genetic testing based on altered patterns of genes responsible for its establishment and progression. It gives valuable insights into commercially available panels for reproducible and accurate prediction of cancer risk.
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Singh, V., Sharma, A., Singh, R. (2023). Genetic Testing in Endometrial Cancer. In: Singh, R. (eds) Genetic Testing in Reproductive Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-99-7028-5_16
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