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Keywords: Streptozotocin
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S-Nitrosoglutathione Attenuates Oxidative Stress and Improves Retention Memory Dysfunctions in Intra-Cerebroventricular-Streptozotocin Rat Model of Sporadic Alzheimer’s Disease via Activation of BDNF and Nuclear Factor Erythroid 2-Related Factor-2 Antioxidant Signaling Pathway

Subject Area:
Neurology and Neuroscience , Psychiatry and Psychology
Harikesh Dubey, Arunabha Ray, Anamika Dubey, Kavita Gulati
Journal: Neuropsychobiology
Neuropsychobiology (2024) 83 (2): 101–113.
https://doi.org/10.1159/000538348
Published Online: 14 May 2024
... was induced by intracerebroventricular infusion of streptozotocin (ICV-STZ, 3 mg/kg) in Wistar rats. The effect of GSNO was analyzed by evaluating the retention of memory in months 1, 2, and 3. After the behavior study, rats were sacrificed and accessed the amyloid beta (Aβ)-40, Aβ42, glutathione (GSH), BDNF...
View article titled, S-Nitrosoglutathione Attenuates Oxidative Stress and Improves Retention Memory Dysfunctions in Intra-Cerebroventricular-<span class="search-highlight">Streptozotocin</span> Rat Model of Sporadic Alzheimer’s Disease via Activation of BDNF and Nuclear Factor Erythroid 2-Related Factor-2 Antioxidant Signaling Pathway
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Journal Articles

Diosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms

Subject Area:
Topic Article Package: Moksha , Neurology and Neuroscience , Psychiatry and Psychology
Narges Mahmoudi, Zahra Kiasalari, Tayebeh Rahmani, Ashkan Sanaierad, Siamak Afshin-Majd, Gholamali Naderi, Tourandokht Baluchnejadmojarad, Mehrdad Roghani
Journal: Neuropsychobiology
Neuropsychobiology (2021) 80 (1): 25–35.
https://doi.org/10.1159/000507398
Published Online: 11 June 2020
... saponins with reported anti-diabetic and numerous protective properties. This research aimed to assess the effect of diosgenin on beneficially ameliorating learning and memory decline in a rat model of type 1 diabetes caused by streptozotocin (STZ) and to explore its modes of action including involvement...
View article titled, Diosgenin Attenuates Cognitive Impairment in <span class="search-highlight">Streptozotocin</span>-Induced Diabetic Rats: Underlying Mechanisms
Open the PDF for Diosgenin Attenuates Cognitive Impairment in <span class="search-highlight">Streptozotocin</span>-Induced Diabetic Rats: Underlying Mechanisms in another window