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Keywords: Intracerebroventricular infusion of streptozotocin
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S-Nitrosoglutathione Attenuates Oxidative Stress and Improves Retention Memory Dysfunctions in Intra-Cerebroventricular-Streptozotocin Rat Model of Sporadic Alzheimer’s Disease via Activation of BDNF and Nuclear Factor Erythroid 2-Related Factor-2 Antioxidant Signaling Pathway

Subject Area:
Neurology and Neuroscience , Psychiatry and Psychology
Harikesh Dubey, Arunabha Ray, Anamika Dubey, Kavita Gulati
Journal: Neuropsychobiology
Neuropsychobiology (2024) 83 (2): 101–113.
https://doi.org/10.1159/000538348
Published Online: 14 May 2024
... was induced by intracerebroventricular infusion of streptozotocin (ICV-STZ, 3 mg/kg) in Wistar rats. The effect of GSNO was analyzed by evaluating the retention of memory in months 1, 2, and 3. After the behavior study, rats were sacrificed and accessed the amyloid beta (Aβ)-40, Aβ42, glutathione (GSH), BDNF...
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