... (cross-fixation). Results: During autobiographical recall, in comparison to the low-level baseline, the BPD patients showed increased brain activity in regions including the posterior hippocampus, the lingual and calcarine cortex, and the precuneus compared to the healthy controls. The BPD patients also...

... of PGRMC1 in the brain, with a special focus on the hippocampus. Treatments of clozapine and AG205 were conducted for 28 days, and subsequent behavioral tests including modified elevated plus maze and Morris water maze were conducted to evaluate the cognitive performance. Hippocampal protein expressions...

..., instructions or products referred to in the content or advertisements. Posttraumatic stress disorder Morphometry Magnetic resonance imaging Amygdala Hippocampus The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) [1], defines posttraumatic stress disorder (PTSD...

.... Region of interest analyses showed increased rs brain connectivity between the hippocampus and the precuneus (implicated in episodic memory); while weaker connectivity was shown between the amygdala and the periaqueductal gray (important for anxiety), and the hippocampus and insula (implicated...

... of treatment with risperidone and compared to a group of matched healthy controls (HC) scanned 6 weeks apart. Unmedicated patients showed reduced blood oxygen level dependent (BOLD) response in several regions, including the hippocampus, and greater BOLD response in regions of the default mode network (DMN...

... with a more limited increase of both the total and left hippocampus volumes. Conclusion: This pilot study is the first to highlight the link between peripheral immune changes and hippocampal volume increase following ECT. Further research is required to conclude whether ECT indeed exerts its central effect...

...) was determined 5 days after the last MA dose to examine anxiety-like behavior. Cytokine and chemokine expressions were measured in the hippocampus using quantitative polymerase chain reaction (qPCR). Human studies were also conducted to evaluate symptoms of anxiety using the General Anxiety Disorder-7 Scale...

... Electroencephalography Hippocampus Medial prefrontal cortex Mood disorders Biomarker Depression Animal model Stress Monoamines Depression is a heterogeneous disorder often manifested by symptoms at psychological, behavioural, and neurophysiological as well as neurochemical levels. Humans experience...

... in the brain plasticity. Previously, we investigated the effects of chronic social stress in the limbic brain structures of Wistar rats (hippocampus, HIPPO, and prefrontal cortex, PFC) and found multiple characteristics that resembled alterations described in some clinical studies of depression. We extended...

... subgroups of schizophrenia based on factor analysis of psychopathology. They have demonstrated a complex pattern of regional changes, where the typical three subgroups might overlap in prefrontal changes, but show divergence in structural deficits in other areas such as the thalamus, hippocampus...

...M. Cagdas Eker; Omer Kitis; Hamza Okur; Ozlem Donat Eker; Erol Ozan; Serhan Isikli; Nurten Akarsu; Ali Saffet Gonul Aim: Serotonin is known for its importance in the pathophysiology of major depressive disorder. Although the hippocampus is one of the key regions in which neurogenesis occurs...

... for spatial learning, we analyzed protein phosphatase 1 (PP1) expression in the hippocampus of mice at various stages of the task and in two groups with different learning abilities. Methods: Mice were trained for 4 days with four trials each day in the MWM. For gene expression hippocampi were prepared 1, 6...

...Ana Djordjevic; Miroslav Adzic; Jelena Djordjevic; Marija B. Radojcic Chronic exposure to stress is associated with different behavioral and neurological syndromes including impaired excitability of nerve cells in hippocampus (HIPPO) and prefrontal cortex (PFC), regions of the brain...

... and oxytocinase could also be associated with this response. The effect of acute immobilization stress on enkephalinase and oxytocinase activities was determined in the soluble and membrane fractions of the medial prefrontal cortex, hippocampus and amygdala using alanyl- and leucyl-beta-naphthylamide...

... analysis. A large number of binding sites for [ 3 H]8-OH-DPAT were observed in the hippocampus, especially the dentate gyrus, CA 1 +CA 2 field, dorsal raphe nucleus and septum. Repeated treatment with ECS, but not repeated imipramine treatment, significantly increased [ 3 H]8-OH-DPAT binding sites...

...Yuji Wada; Hidehiro Hasegawa; Mitsuhiko Nakamura; Nariyoshi Yamaguchi This study assessed the effects of MK-801 (0.1 and 0.5 mg/kg), a noncompeti-tive antagonist of N-methyl- D -aspartate receptors, on focal seizure activity elicited by electrical stimulation to the feline hippocampus. Neither...

...Yuji Wada; Hidehiro Hasegawa; Mitsuhiko Nakamura; Nariyoshi Yamaguchi To clarify the role of the serotonergic system in limbic and thalamic epileptic activity, we examined the effects of 5-hydroxytryρtophan (5-HTP, 20 and 40 mg/kg) on fully kindled seizures from the hippocampus and lateral...

...Izumi Hotta; Shigeto Yamawaki; Tomio Segawa The effects of lithium treatment on serotonin (5-HT) receptors in rat frontal cortex and hippocampus were investigated. Long-term lithium treatment strongly blocked 5-hydroxytryptophan-induced head twitches, while acute lithium administration by itself...

..., instructions or products referred to in the content or advertisements. ACTH Hippocampus Rhythmic slow activity Behavior Rabbits Neuropsychobiology 17: 169-172 (1987) © 1987 S. Kargcr AG. Basel 0302-282X/87/0I73-0I69S2.75/0 Different Effects of ACTH Fragments on Hippocampal EEG and Behavior...

... griseum, nucleus septi lateralis, hippocampus, striae longitudinales of Lancisi, bandeletta diagonalis of Broca, pallidum, hypothalamus, hypophysis and neocortex. Some DSIP pathways seem likely: (1) indusium griseum – striae longitudinales – hippocampus; (2) nucleus septi lateralis – striae longitudinales...