...Anett Schumacher; Jessica Muha; Susan C. Campisi; Glyneva Bradley-Ridout; Andy C.H. Lee; Daphne J. Korczak Introduction: Neurobiological dysfunction is associated with depression in children and adolescents. While research in adult depression suggests that inflammation may underlie the association...

... occupational therapy program incorporating mindfulness (MOT) as a form of psychiatric rehabilitation to ameliorate residual social and occupational impairment in patients with anxiety disorders and depression. The objective was to evaluate the effects of MOT on their personal well-being and to assess...

...Sarah Schumacher; Sebastian Laufer; Susanne Fischer Introduction: Elevated levels of the hypothalamic-pituitary-adrenal axis hormone cortisol are a frequently replicated finding in major depressive disorder (MDD). However, the current state of research is inconclusive as to whether hypercortisolism...

...Laura Wade-Bohleber; Niklaus Zoelch; Mick Lehmann; Jutta Ernst; André Richter; Erich Seifritz; Heinz Boeker; Simone Grimm Introduction: Psychodynamic psychotherapy is an effective and widely used treatment for major depressive disorder (MDD); however, little is known about neurobiological changes...

...Yue Yu; Yue Chen; Yue Wu; Tongjian Bai; Qiang Wei; Yang Ji; Ting Zhang; Chenglong Li; Aiguo Zhang; Kai Wang; Yanghua Tian Introduction: Somatic symptoms often occur as a manifestation of depression and anxiety. The subgenual anterior cingulate cortex (sgACC) has been shown to be closely related...

...Guixing Xu; Qiwei Xiao; Biqing Huang; Hanzhou Lei; Zihan Yin; Liuyang Huang; Zhuo Zhou; Hao Tian; Fengyuan Huang; Yilin Liu; Mingsheng Sun; Ling Zhao; Fanrong Liang Introduction: Depression is the most significant contributor to non-fatal health reductions worldwide. Acupuncture is the most...

...Qi Wang; Hongsheng Bi; Hongfei Huang; Yitong Wang; Lili Gong; Na Qi; Dongdong Li; Xin Jin; Tianchao Xu; Baoguang Shi Background: The precise physiological mechanisms of acupuncture in the treatment of depression are still unknown. This study aimed to observe the effects of electroacupuncture (EA...

... (35 depressed and 32 [hypo] manic) and 29 healthy controls were included. Cognitive functioning was assessed at 3 time intervals (baseline, 4, and 8 months) assessing processing speed, sustained attention, verbal memory, working memory, and response inhibition. Plasma samples for quantification of 3...

... and occipital alpha-1 and alpha-2) and power (frontal midline theta) assessed at baseline and 1 week after initiation of pharmacological depression treatment while presenting affective stimuli. We then compared week 4 responders and nonresponders to antidepressant treatment. Results: Follow-up analyses...

... Rodrigues de Carvalho; Marta Maria de França Fonteles; Stanley Juan Chavez Gutierrez; José Maria Barbosa-Filho; Francisca Cléa Florenço de Sousa Background: Depression is a common, chronic, and often recurrent serious mood disorder. Conventional antidepressants present limitations that stimulate the search...

..., and IL-10 are related to changes in cognitive functioning following ECT. Methods: In the week before and 1 week after an acute course of ECT, 62 patients suffering from depression underwent a neuropsychological evaluation to assess their processing speed using the Symbol Digit Substitution Test (SDST...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Psychotherapy Augmentation Depression Anxiety Clinical psychology In fact...

...Jillian S. Hardin; Nancy Aaron Jones; Krystal D. Mize; Melannie Platt Background: While numerous studies have demonstrated maternal depression’s influence on infant brain development, few studies have examined the changes that occur as a consequence of co-occurring experiential factors that affect...

...Shunsuke Tanahashi; Hisashi Tanii; Yoshiaki Konishi; Takeshi Otowa; Tsukasa Sasaki; Mamoru Tochigi; Yuji Okazaki; Hisanobu Kaiya; Motohiro Okada Introduction: Panic disorder (PD) has many comorbidities such as depression, bipolar disorder (BPD), and agoraphobia (AG). PD is a moderately heritable...

...Xiaofeng Guan; Qi Wang; Mengxi Liu; Anji Sun; Xiaobai Li Introduction: The interleukin-6/janus kinase 2/signal transducer and activator of transcription 3 (IL-6/JAK2/STAT3) pathway plays an important role in immune function, but little research has focused on this pathway in depression. We sought...

... of soluble T. gondii antigen (STAg) in pregnant Balb/c mice at E6 or E16. Adult male offspring were evaluated for anxiety-like and depressive-like behavior in elevated plus maze (EPM) and forced swimming test (FST). Results: In FST, immobility time at E6 and E16 increased when the mothers were treated...

...Teresa Massardo; Juan Carlos Quintana; Rodrigo Jaimovich; Claudia G. Sáez; Luis Risco; Claudio Liberman; Aída Verónica Araya; Tamara Galleguillos; Gabriel Castro-Mora; Jaime Pereira Background: Major depressive disorder (MDD) is an important independent risk factor for cardiovascular disease...

...Margarita M. Maramis; Marlina S. Mahajudin; Junaidi Khotib Introduction: Depressive disorders are the 4th leading cause of health problems and the 2nd leading cause of burden among all diseases. Almost all depressive disorder patients have cognitive impairments to a certain extend. Studies about...

...Yuan Guo; Li Zhang; Jin Zhang; Shu-Xuan Lv; Cheng-Xue Du; Tao Wang; Hui-Sheng Wang; Wen Xie; Jian Liu Background: The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. Objectives...

.... This results in a high percentage of misdiagnosis and consequential inefficient treatment; especially regarding major depressive disorder (MDD), depression in the context of bipolar disorder (BD-D), bipolar disorder with manic symptoms (BD-M), and psychosis in the context of schizophrenia (SZ). Objective...