... years, investigating presynaptic or postsynaptic markers, such as DA receptor and DA transporter availability, both with and without challenge. This review summarizes SPECT and PET studies on different levels of alcohol consumption to support the dimensional view of alcohol use disorder (AUD), ranging...

...Warren B. Logge; Kirsten C. Morley; Paul S. Haber; Andrew J. Baillie Introduction: Individuals with alcohol use disorder (AUD) have difficulties regulating alcohol consumption, despite adverse drinking-related consequences. This may be due to incapacity incorporating previous negative feedback from...

...Miriam Sebold; Stefan J. Kiebel; Michael N. Smolka; Andreas Heinz; Lorenz Deserno Alcohol use disorder (AUD) is characterized by a combination of symptoms including excessive craving, loss of control, and progressive neglect of alternative pleasures. A mechanistic understanding of what drives...

...Werner Fey; Frauke Conring; Andrea Federspiel; Leonie Steiner; Franz Moggi; Maria Stein Introduction: In individuals with alcohol use disorder (AUD), the brain areas underlying cue-induced reactions (e.g., cingulum, striatum, thalamus) and altered activation of these regions have been identified...

...Gianna Spitta; Tobias Gleich; Kristin Zacharias; Oisin Butler; Ralph Buchert; Jürgen Gallinat Introduction: Reduced striatal dopamine D2/3 receptor availability in alcohol use disorder (AUD) has been demonstrated in recent clinical studies and meta-analyses. However, only a limited number...